Press release
Non-covid mRNA Vaccine and Therapeutics Market Exclusive Report on the Latest Revenue and Future Scope
InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Non-covid mRNA Vaccine and Therapeutics Market Size, Share & Trends Analysis Report By Product Type (mRNA Therapeutic, mRNA Vaccines), By Therapeutic Area (Infectious Diseases, Oncological Disorders, Other Disorders), By Route of Administration (Intravenous, Intramuscular, Intranasal, Others)- Market Outlook and Industry Analysis 2031"The Global Non-covid mRNA Vaccine and Therapeutics Market is valued at US$ 370.0 Mn in 2024, and it is expected to reach US$ 1,684.80 Mn by 2031, with a CAGR of 24.20% during the forecast period of 2024-2031.
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Advances in mRNA technology have significantly accelerated progress in therapeutic and vaccine development, positioning the non-COVID mRNA vaccines and therapeutics market for substantial growth. This platform leverages synthetic messenger RNA to instruct cells to produce targeted proteins that can prevent, manage, or treat a broad spectrum of conditions, including infectious diseases, cancer, and select genetic disorders.
The scope of applications for non-COVID mRNA-based therapies is extensive and highly impactful. mRNA vaccines are under active development for infectious diseases such as influenza, HIV, and Zika, with the objective of generating strong and durable immune responses. In the field of oncology, personalized mRNA vaccines designed to encode tumor-specific antigens are being developed to stimulate the immune system to identify and eliminate cancer cells based on individual patient tumor characteristics.
List of Prominent Players in the Non-covid mRNA Vaccine and Therapeutics Market:
• CureVac
• Anima Biotech
• Arcturus Therapeutics
• BioNTech (Pfizer)
• eFFECTOR Therapeutics, Inc.
• eTheRNA
• Ethris (AstraZeneca)
• H3 Biomedicine Inc. (Eisai Inc.)
• In-Cell-Art
• Ionis Pharmaceuticals, Inc.
• Kernal Biologics
• Moderna
• RNAimmune (Sirnaomics)
• Silence Therapeutics
• Skyhawk Therapeutics, Inc.
• Stemirna Therapeutics Co., Ltd.
• Tiba Biotechnology
• Translate Bio Sanofi)
• Ziphius Therapeutics NV
Market Dynamics:
Drivers:
The expansion of the non-COVID mRNA vaccines and therapeutics market is largely driven by technological progress that has improved product stability, delivery efficiency, and therapeutic effectiveness, particularly through advancements in lipid nanoparticle (LNP) delivery systems. The broad and growing range of applications including infectious disease prevention, personalized oncology treatments, and therapies for genetic disorders continues to widen the market opportunity. Furthermore, the rapid development and scalable manufacturing capabilities demonstrated during the COVID-19 pandemic have reinforced mRNA technology as a dependable platform for large-scale therapeutic production.
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Challenges:
Despite strong momentum, the market faces several technical and operational constraints. Fragmented manufacturing workflows that rely on multiple external suppliers often lead to inefficiencies and delays, posing challenges especially for smaller organizations with limited operational capacity. In addition, constrained access to GMP-compliant raw materials can create supply bottlenecks.
Regional Trends:
North America holds a leading position in the non-COVID mRNA vaccines and therapeutics market, supported by a well-developed research and development ecosystem, the presence of major pharmaceutical and biotechnology companies, and strong academic research capabilities. This integrated environment promotes innovation, strategic partnerships, and sustained investment in mRNA technologies.
Recent regulatory approvals, such as the U.S. FDA authorization of Moderna's mRNA-based RSV vaccine for older adults, highlight the region's continued leadership. Additionally, supportive regulatory policies and robust public-private collaborations are accelerating clinical progress and the commercialization of next-generation mRNA therapies.
Recent Developments:
• In Jan 2023, Moderna, Inc. announced a definitive agreement to acquire OriCiro for $85 million. This acquisition provides Moderna with advanced tools for cell-free synthesis and amplification of plasmid DNA, a crucial component in the mRNA manufacturing process.
• In Aug 2021, Sanofi entered into a definitive agreement to acquire Translate Bio, a clinical-stage mRNA therapeutics company, for $38.00 per share in cash, totaling approximately $3.2 billion. Both companies' Boards of Directors have unanimously approved the transaction, aiming to accelerate Sanofi's development of mRNA-based therapeutics and vaccines.
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Segmentation of Non-covid mRNA Vaccine and Therapeutics Market-
Non-covid mRNA Vaccine and Therapeutics Market- By Product Type
• mRNA Therapeutic
• mRNA Vaccines
Non-covid mRNA Vaccine and Therapeutics Market- By Therapeutic Area
• Infectious Diseases
o Influenza
o Respiratory Syncytial Virus (RSV)
o Cytomegalovirus
o Others
• Oncological Disorders
• Other Disorders
Non-covid mRNA Vaccine and Therapeutics Market- By Route of Administration
• Intravenous
• Intramuscular
• Intranasal
• Others
Non-covid mRNA Vaccine and Therapeutics Market- By Region
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of Middle East and Africa
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