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Inflammatory Diseases Biologics Market to Reach US$ 157.31 Billion by 2033, Driven by Rising Autoimmune Prevalence and Biosimilar Expansion | DataM Intelligence
Inflammatory Diseases Biologics Market
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United States Key Industry Developments
☑️ January 2026: AbbVie reported strong continued uptake of Skyrizi and Rinvoq for psoriasis and rheumatoid arthritis, with expanded indications and biosimilar competition driving market share strategies.
☑️ January 2026: Johnson & Johnson announced positive real-world data for Tremfya in inflammatory bowel disease, reinforcing its position in the interleukin antagonist segment.
☑️ December 2025: Amgen expanded patient access programs for Enbrel biosimilars, securing additional formulary placements in major U.S. health systems amid cost pressures.
☑️ December 2025: Eli Lilly and Company highlighted growing adoption of its IL-17 and IL-23 inhibitors in dermatology clinics, supported by new clinical trial outcomes.
Japan Key Industry Developments
☑️ January 2026: Japanese regulatory authorities approved additional indications for key TNF and IL inhibitors, accelerating reimbursement and adoption in rheumatoid arthritis and ankylosing spondylitis treatments.
☑️ January 2026: Local and global players, including Takeda Pharmaceuticals, showcased advanced biologics portfolios at major rheumatology and gastroenterology conferences in Tokyo.
☑️ December 2025: Increased focus on biosimilar entry and next-generation JAK inhibitors, with several facilities reporting higher biologic utilization rates in autoimmune care.
Key Mergers and Acquisitions
✦ Eli Lilly and Company announced a definitive agreement to acquire Ventyx Biosciences for approximately US$ 1.2 billion (all-cash transaction at $14.00 per share), bolstering its oral therapies pipeline for inflammatory-mediated diseases including NLRP3 inflammasome inhibitors, with closing expected in the first half of 2026 (announced January 7, 2026).
✦ AbbVie entered advanced discussions to potentially acquire Revolution Medicines for over US$ 20 billion, targeting its pan-RAS oncology platform with potential applications in inflammatory and related pathways (reports surfaced January 7, 2026).
✦ Sanofi continued its acquisitive strategy with ongoing integration and follow-on deals in immunology, building on recent 2025 acquisitions while positioning for new inflammatory asset bolt-ons in early 2026.
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Market Segmentation Analysis
By Drug Class: Anti-Tumor Necrosis Factor (TNF) inhibitors dominate with 44.3% market share in 2024; followed by Interleukin antagonists, Janus Kinase (JAK) inhibitors, and Others.
By Disease Indication: Rheumatoid Arthritis holds the largest share at 40.3% in 2024; followed by Psoriasis, Inflammatory Bowel Disease, Ankylosing Spondylitis, and Others.
By Distribution Channel: Hospital Pharmacies lead; followed by Retail Pharmacies.
Regional Insights
North America commands the largest market share in the global Inflammatory Diseases Biologics market with 48.5% in 2024, supported by advanced healthcare infrastructure, high biologic penetration, favorable reimbursement policies, strong clinical adoption of TNF inhibitors and newer agents, and the presence of leading pharmaceutical companies driving innovation and market access.
Asia-Pacific remains the fastest-growing region with a CAGR of 7.7% in 2024, fueled by rising autoimmune disease burden, increasing healthcare expenditure, rapid biosimilar adoption, expanding access to specialty care, government initiatives for chronic disease management, and growing partnerships with global players.
Growth Drivers
✦ Escalating prevalence of rheumatoid arthritis, psoriasis, IBD, and other inflammatory conditions
✦ Dominance and sustained efficacy of TNF inhibitors with expanding biosimilar competition
✦ Advancements in interleukin antagonists and JAK inhibitors improving treatment outcomes
✦ Rising patient access through reimbursement and biosimilar affordability
✦ Strategic pipeline expansions, regulatory approvals, and regional market penetration
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Key Players
The market includes leading companies such as Amgen Inc., Novartis Pharmaceuticals Corporation, Johnson & Johnson, Pfizer Inc., F. Hoffmann-La Roche Ltd, GSK, AbbVie, Sanofi, Eli Lilly and Company, Takeda Pharmaceuticals U.S.A., Inc., and others.
Key Highlights (Top 5 Key Players)
✦ AbbVie - Leading with Skyrizi and Rinvoq portfolios dominating psoriasis and RA markets.
✦ Johnson & Johnson - Dominating through Tremfya and Stelara in IBD and dermatology indications.
✦ Amgen Inc. - Strong in TNF inhibitors with Enbrel and emerging biosimilar leadership.
✦ Sanofi - Advancing interleukin and JAK pathways for multiple inflammatory conditions.
✦ Eli Lilly and Company - Growing rapidly with IL-17/IL-23 inhibitors in autoimmune diseases.
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