United States Oncolytic Viral Therapy Market to hit US$ 164.51 Million by 2033 | North America's Led by 45% Market Share | Top Companies - Coastar Theapeutics Inc., IconOVir Bio, Inc., and Calidi Biotherapeutics, Inc

Oncolytic Viral Therapy Market Size reached US$ 24.48 Million in 2024 and is expected to reach US$ 164.51 Million by 2033, growing at a CAGR of 23.8% during the forecast period 2025-2033.

DataM Intelligence unveils its latest report on the "Oncolytic Viral Therapy Market Size 2025," offering an in-depth analysis of market trends, growth drivers, competitive landscape, and regional dynamics. The study covers market size in value and volume, CAGR forecasts, and emerging opportunities that can guide businesses in seizing growth potential and crafting winning strategies. Packed with data-driven insights on current developments and future trends, this report is essential for companies aiming to stay ahead in the competitive Market.

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United States: Recent Industry Developments

✅ December 2025: U.S. biotech firms reported promising late-stage data showing improved tumor regression with new oncolytic viral therapy candidates in melanoma and glioblastoma.

✅ November 2025: A major clinical trial expanded to include combination therapy of oncolytic viruses with immune checkpoint inhibitors, addressing hard-to-treat solid tumors.

✅ October 2025: Regulatory discussions advanced as key stakeholders pushed for updated guidance on accelerated approval pathways for novel oncolytic platforms.

Japan: Recent Industry Developments

✅ December 2025: Japanese research institutions published results on optimized viral vectors demonstrating enhanced targeting and reduced off-target effects in preclinical models.

✅ November 2025: Collaboration agreements formed between pharma companies and academic groups to co-develop oncolytic therapies for gastrointestinal cancers.

✅ October 2025: Clinical sites in Japan commenced new early-phase studies evaluating safety and dosing of next-gen oncolytic viruses in solid tumors.

List of Top Key Player:

Amgen, Inc., Daiichi Sankyo Co., Ltd., Lokon Pharma AB, Virogin Biotech Canada Ltd, KaliVir Immunotherapeutics, Inc., Transgene SA, Vyriad, Inc., Coastar Theapeutics Inc., IconOVir Bio, Inc., and Calidi Biotherapeutics, Inc

USA - Industry Developments:
✅ 12 Feb 2025 - Amgen, Inc. advanced clinical research activities focused on expanding the therapeutic potential of oncolytic viruses in solid tumor treatment.
✅ 28 Mar 2025 - Calidi Biotherapeutics, Inc. reported progress in preclinical development of novel oncolytic virus platforms designed to enhance tumor targeting.

Japan - Industry Developments:
✅ 06 May 2025 - Daiichi Sankyo Co., Ltd. strengthened its oncology research pipeline by increasing investments in viral-based cancer immunotherapies.
✅ 19 Jul 2025 - Japanese research institutions intensified collaboration with biotech companies to accelerate oncolytic virus clinical trials.

Korea - Industry Developments:
✅ 09 Jan 2025 - Korean biotech firms expanded early-stage research programs focused on genetically engineered oncolytic viruses for personalized cancer treatment.
✅ 22 Jun 2025 - Government-backed research centers in Korea increased funding support for translational studies in viral immuno-oncology.

Forecast Projection:

The Global Oncolytic Viral Therapy Market is poised for significant growth between 2025 and 2033. In 2024, the market maintained a steady upward trajectory, and with strategic initiatives by leading players accelerating adoption, the market is expected to soar throughout the forecast period. Companies leveraging these trends are well-positioned to capture emerging opportunities and maximize revenue potential.

Market Intelligence Research Process:

The Oncolytic Viral Therapy Market research report by DataM Intelligence combines primary and secondary data to deliver deep, actionable insights. It examines the full spectrum of factors shaping the industry, from government regulations and market conditions to competitive dynamics, historical trends, technological breakthroughs, upcoming innovations, and potential challenges. This comprehensive analysis not only highlights growth prospects but also identifies barriers, equipping businesses to navigate market volatility and capitalize on emerging opportunities.

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Key Segmentation:

By Virus Type: Adenoviruses, Herpes Simplex Virus, Maraba Virus, Measles, Newcastle Disease Virus, Picornavirus, Reovirus, Vaccinia Virus, Vesicular Stomatitis Virus, Others

By Application: Melanoma, Breast Cancer, Prostate Cancer, Ovarian Cancer, Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Head and Neck Cancer, Others

By Mode of Administration: Intratumoral Injection, Intravenous Infusion, Intracavitary Injection, Others

By End-User: Hospitals, Oncology Centers, Ambulatory Surgical Centers, Cancer Research Institutes, Others

Growth Regional Analysis:

1. North America - 45%
Largest share driven by strong clinical trial activity, FDA approvals, and high oncology R&D investment.

2. Europe - 28%
Supported by advanced healthcare infrastructure, increasing cancer incidence, and active academic research programs.

3. Asia-Pacific - 18%
Growing rapidly due to expanding biotech ecosystems, rising cancer burden, and government support for innovative therapies.

4. Middle East & Africa - 5%
Early-stage adoption led by improving oncology care facilities and selective investments in advanced cancer treatments.

5. South America - 4%
Gradual growth supported by expanding cancer treatment access and increasing participation in global clinical trials.

Benefits of the Report:

Chapter 1 - Market Overview: Kickstarts the report with a comprehensive snapshot of the Oncolytic Viral Therapy Market, summarizing key segments by region, product type, and application. Highlights include market size, segment growth potential, and short- & long-term industry outlook.

Chapter 2 - Emerging Trends: Uncovers the game-changing trends and high-impact innovations shaping the future of the industry.

Chapter 3 - Competitive Landscape: Offers a deep dive into market competition, detailing revenue shares, strategic initiatives, and recent mergers & acquisitions.

Chapter 4 - Top Player Profiles: Features detailed company profiles, covering revenue, profit margins, product lines, and major milestones for leading market players.

Chapters 5 & 6 - Regional & Country Analysis: Breaks down revenue performance across global regions, providing insights on market sizes, opportunities, and growth prospects worldwide.

Chapter 7 - Segmentation Analysis: Explores market segmentation by type, revealing high-potential categories and guiding businesses towards lucrative areas.

Chapter 8 - Application Insights: Examines downstream markets and identifies promising sectors for expansion, showing how different applications are driving growth.

Chapter 9 - Supply Chain Mapping: Maps the entire industry supply chain, highlighting upstream and downstream activities for a holistic market perspective.

Chapter 10 - Key Takeaways: Concludes with critical insights and actionable strategies, equipping stakeholders to make informed decisions and stay ahead in the market.

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FAQ's

Q1: What is the current size of the Oncolytic Viral Therapy Market and its future potential?

A: The Oncolytic Viral Therapy Market was valued at US$ 24.48 Million in 2024 and is projected to surge to US$ 164.51 Million by 2033

Q2: How fast is the Oncolytic Viral Therapy Market expected to grow in the coming years?

A: The market is forecast to expand at a robust CAGR of 23.8% between 2025-2033, signaling strong global growth and investment potential.

Q3: Which regions are dominating the Oncolytic Viral Therapy Market and which are fastest-growing?

A: North America region is expected to hold the largest market share over the forecast period.

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