Press release
Multiple System Atrophy Market in the 7MM is projected to grow at a CAGR of 50.60% by 2034, estimates DelveInsight
DelveInsight's "Multiple System Atrophy Market Insight, Epidemiology and Market Forecast - 2034" report delivers an in-depth understanding of Multiple System Atrophy, historical and forecasted epidemiology as well as the Multiple System Atrophy market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.Unlock detailed insights into the Multiple System Atrophy Market by downloading the comprehensive report from DelveInsight @ Multiple System Atrophy Therapeutics Market [https://www.delveinsight.com/sample-request/multiple-system-atrophy-msa-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Key Takeaways from the Multiple System Atrophy Market Report
* In December 2025, PepGen Inc . initiated a phase 2 study is to learn about the effects of an investigational medicine, PGN-EDODM1, to see how safe and tolerable multiple administrations of PGN-EDODM1 are for people with myotonic dystrophy type 1 (DM1) compared to placebo.
* In December 2025, H. Lundbeck A/S conducted a study will consist of a screening period of 10 days up to 6 weeks, a 72-week placebo-controlled period (PCP), and will include a 72-week optional dose-blinded open-label treatment extension (OLE) period. Participants in the PCP will be randomized to amlenetug high dose, amlenetug low dose or placebo (1:1:1). All participants entering the OLE will receive amlenetug during the OLE. Participants will receive intravenous infusions approximately every 4 weeks during both the PCP and OLE.
* In December 2025, Teva Branded Pharmaceutical Products R&D LLC announced a study is to evaluate the efficacy of TEV-56286 administered orally for the treatment of adult participants with Multiple System Atrophy (MSA). A secondary objective of the study is to evaluate specific efficacy parameters of TEV-56286. Another secondary objective is to evaluate the safety and tolerability of TEV-56286. The planned study period per participant is 56 weeks including a screening period (up to 4 weeks), a 48-week double-blind treatment period, and a follow-up visit (approximately 4 weeks after the end of the double-blind treatment period). The study duration will be approximately 27 months.
* In 2023, the US accounted for the highest prevalent cases of Multiple System Atrophy with approximately 42,500 cases, which are expected to increase by 2034 at a CAGR of 1.0%.
* In 2023, the Germany reported the highest number of prevalent cases of Multiple System Atrophy among the EU4 and the UK, with approximately 2,700 cases. UK followed with around 2,400 cases, while Spain recorded the lowest prevalent cases, with nearly 1,500 cases.
* In 2023, Japan reported approximately 5,100 prevalent cases of Multiple System Atrophy in males and 12,000 cases in females, with numbers projected to rise by 2034.
* In the US, the number of cases in 2023 were as follows: around 400 cases in stage 0, around 800 in stage 1, ~2,100 in stage 2, ~15,000 in stage 3, ~13,000 in stage 4, and ~10,000 in stage 5 and these numbers projected to rise by 2034.
* In Japan, around 30% of Multiple System Atrophy cases reported in 2023 were associated with Multiple System Atrophy-P, while 70% were linked to Multiple System Atrophy-C, indicating that Multiple System Atrophy-C is the dominant type than Multiple System Atrophy-P.
* In 2023, Germany recorded the highest number of Multiple System Atrophy around 1,400 cases in the 70 years and above age group. Among the age groups 50-59 years and 60-79 years, the 70 years and above group is expected to see an increase to 1,500 cases by 2034.
* In 2023, Japan recorded around 13,700 cases of symptomatic nOH in Multiple System Atrophy patients, with the number projected to reach around 14,100 cases by 2034.
* The leading Multiple System Atrophy Companies such as H Lundbeck A/S, Brain Neurotherapy Bio, Inc., Asklepios BioPharmaceutical, Inc., Theravance Biopharma, Ono Pharmaceutical Co. Ltd, Ionis Pharmaceuticals, Inc., Biogen, Alterity Therapeutics, Teva Pharmaceutical, MODAG GmbH , and others.
* Promising Multiple System Atrophy Therapies such as TEV-56286, YA-101, Foralumab Nasal, Verdiperstat, TAK-341, ATH434, Safinamide Methanesulfonate, Rasagiline Mesylate, ONO-2808, AZD3241 , and others.
Gain a competitive edge in the Multiple System Atrophy Market by exploring our in-depth analysis. Visit our website to access the full report and make informed strategic decisions @ Multiple System Atrophy Treatment Drugs [https://www.delveinsight.com/sample-request/multiple-system-atrophy-msa-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Multiple System Atrophy Epidemiology Segmentation in the 7MM
* Diagnosed Prevalent Cases of Multiple System Atrophy
* Gender-specific Diagnosed Prevalent Cases of Multiple System Atrophy
* Age-specific Diagnosed Prevalent Cases of Multiple System Atrophy
* Type-specific Diagnosed Prevalent Cases of Multiple System Atrophy
* Stage-specific Diagnosed Prevalent Cases of Multiple System Atrophy
Download the report to understand which factors are driving Multiple System Atrophy Epidemiology Trends @ Multiple System Atrophy Prevalence [https://www.delveinsight.com/sample-request/multiple-system-atrophy-msa-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Multiple System Atrophy Drugs Market
Multiple System Atrophy treatment primarily focuses on symptom management, as there is no cure. Pharmacological therapies, such as levodopa for Parkinsonism and other medications for autonomic dysfunction, cerebellar ataxia, and sleep disturbances, are commonly used. Immunotherapy is not typically part of Multiple System Atrophy treatment, as it targets underlying protein aggregation rather than immune response. Emerging therapies include Amlenetug, Ampreloxetine, ATH434, TAK-341/MEDI1341 and Emrusolmin (Anle138b).
Emerging Multiple System Atrophy Drugs
* Emrusolmin (TEV-56286, Anle-138b): Teva Pharmaceutical/MODAG GmBH
Anle138b is a small molecule designed to target toxic alpha-synuclein oligomers, dissolving them and preventing new formations, thus addressing neurodegenerative disorders. Preclinical studies show it halts disease progression. Unlike antibody treatments, it is orally administered and crosses the blood-brain barrier. In July 2022, it received orphan drug designation for Multiple System Atrophy and is currently in Phase II Multiple System Atrophy clinical trials.
* Amlenetug (Lu AF82422): H. Lundbeck A/S/Genmab
Lu AF82422 is a human monoclonal antibody designed to target toxic alpha-synuclein proteins involved in Multiple System Atrophy pathology. It seeks to slow or stop disease progression by clearing these harmful proteins. The compound has demonstrated effectiveness in Phase II and has received orphan drug and SAKIGAKE designations. It is now in Phase III trials.
* Ampreloxetine (TD-9855): Theravance Biopharma
Ampreloxetine is an investigational norepinephrine reuptake inhibitor being developed for symptomatic neurogenic orthostatic hypotension (nOH) in Multiple System Atrophy patients. It increases norepinephrine levels by blocking its transporters. Currently in Phase III trials, it has received ODD status from the US FDA and patent protection until 2037.
Discover key developments and opportunities in the Multiple System Atrophy Market. Click here to learn more from DelveInsight's latest report @ Multiple System Atrophy Market Size [https://www.delveinsight.com/sample-request/multiple-system-atrophy-msa-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Multiple System Atrophy Companies
H Lundbeck A/S, Brain Neurotherapy Bio, Inc., Asklepios BioPharmaceutical, Inc., Theravance Biopharma, Ono Pharmaceutical Co. Ltd, Ionis Pharmaceuticals, Inc., Biogen, Alterity Therapeutics, Teva Pharmaceutical, MODAG GmbH , and others.
Multiple System Atrophy Market Outlook
Multiple System Atrophy is a rare neurodegenerative disorder that typically begins in adulthood, usually after age 30. It shares symptoms with Parkinson's disease, such as Parkinsonism, but also includes additional features like cerebellar ataxia and autonomic dysfunction, affecting involuntary processes such as heart rate and blood pressure. Multiple System Atrophy is classified as Multiple System Atrophy-P when Parkinsonism predominates, and Multiple System Atrophy-C when cerebellar symptoms are more prominent. Currently, no disease-modifying treatments are approved for Multiple System Atrophy, offering a significant opportunity for pharmaceutical Multiple System Atrophy companies to develop the first effective therapies. Existing Parkinson's treatments like levodopa have limited effectiveness, underscoring the need for targeted treatments for Multiple System Atrophy.
Download DelveInsight's Multiple System Atrophy Market report today and stay ahead in this rapidly evolving field. @ Multiple System Atrophy Clinical Trials [https://www.delveinsight.com/sample-request/multiple-system-atrophy-msa-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Scope of the Multiple System Atrophy Market Report
* Coverage- 7MM
* Study Period- 2020-2034
* Multiple System Atrophy Companies- H Lundbeck A/S, Brain Neurotherapy Bio, Inc., Asklepios BioPharmaceutical, Inc., Theravance Biopharma, Ono Pharmaceutical Co. Ltd, Ionis Pharmaceuticals, Inc., Biogen, Alterity Therapeutics, Teva Pharmaceutical, MODAG GmbH , and others.
* Multiple System Atrophy Pipeline Therapies- TEV-56286, YA-101, Foralumab Nasal, Verdiperstat, TAK-341, ATH434, Safinamide Methanesulfonate, Rasagiline Mesylate, ONO-2808, AZD3241 , and others.
* Multiple System Atrophy Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
* Multiple System Atrophy Unmet Needs, KOL's views, Analyst's views, Multiple System Atrophy Market Access and Reimbursement
Table of Contents
1. Key Insights
2. Multiple System Atrophy Market Report Introduction
3. Country-wise Multiple System Atrophy Market Overview at a Glance
4. Multiple System Atrophy Market Overview by Therapeutic Class
5. Methodology of Multiple System Atrophy Epidemiology and Market
6. Multiple System Atrophy Executive Summary
7. Key Events
8. Multiple System Atrophy Disease Background and Overview
9. Multiple System Atrophy Epidemiology and Patient Population
10. Multiple System Atrophy Patient Journey
11. Multiple System Atrophy Marketed Drugs
12. Multiple System Atrophy Emerging Drugs
13. Multiple System Atrophy: Market Analysis
14. Key Opinion Leaders' Views
15. Multiple System Atrophy SWOT Analysis
16. Multiple System Atrophy Unmet Needs
17. Multiple System Atrophy Market Access and Reimbursement
18. Appendix
19. Multiple System Atrophy Report Methodology
20. DelveInsight Capabilities
21. Disclaimer
About Us
DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.
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