High-performance Liquid Chromatography (HPLC) Market to Reach US$ 4.42 Billion by 2031, Supported by Rising Demand for High-Precision Analytical Solutions

Market Summary -

The global market for High-performance Liquid Chromatography (HPLC) was estimated to be worth US$ 3,529 million in 2024 and is forecast to reach a readjusted size of US$ 4,416 million by 2031, expanding at a CAGR of 3.3% during the forecast period 2025-2031.

According to QY Research, a new publication titled "High-performance Liquid Chromatography (HPLC) Market Share and Ranking, Overall Sales and Demand Forecast 2025-2031" provides an in-depth, data-driven analysis of the global HPLC market to support informed decision-making and sustainable growth strategies. Authored by experienced market analysts and subject-matter experts, the report delivers accurate market data, validated insights, and actionable recommendations for industry participants. It evaluates historical performance alongside future forecasts to clearly explain competitive dynamics, key growth drivers, market challenges, and emerging opportunities. With detailed coverage of market dynamics, segmentation, leading companies, and regional trends, this comprehensive report serves as a reliable strategic resource for businesses seeking to strengthen their position in the global HPLC market.

Get Full PDF Sample Copy of the Report (Including Full TOC, Tables & Charts):
https://www.qyresearch.in/request-sample/machinery-equipment-high-performance-liquid-chromatography-hplc-market-share-and-ranking-overall-sales-and-demand-forecast-2025-2031

The potential shifts in the 2025 U.S. tariff framework pose substantial volatility risks to global markets. This report provides a comprehensive assessment of recent tariff adjustments and international strategic countermeasures on High-performance Liquid Chromatography (HPLC) cross-border industrial footprints, capital allocation patterns, regional economic interdependencies, and supply-chain reconfigurations.

High-performance liquid chromatography (HPLC) is a core analytical technique used to separate, identify, and quantify components in complex mixtures. By pumping a pressurized liquid solvent through a column packed with solid adsorbent material, HPLC enables highly accurate and reproducible separation based on differential interactions between sample components and the stationary phase. Owing to its precision, reliability, and adaptability, HPLC has become an indispensable tool across pharmaceuticals, biotechnology, food safety, environmental monitoring, and chemical analysis.

Market Trend -
The global HPLC market is witnessing steady growth driven by expanding applications in pharmaceutical quality control, biologics characterization, metabolomics, and environmental testing. Regulatory authorities worldwide continue to enforce stricter standards for drug safety, food quality, and environmental compliance, encouraging laboratories to invest in advanced chromatographic systems. Technological developments-such as improved detectors, enhanced column chemistries, automation, and advanced data-processing software-are further strengthening the role of HPLC as a gold-standard analytical platform. While newer techniques such as UPLC are emerging, conventional HPLC remains widely adopted due to its robustness, established workflows, and broad user base.

Market Drivers, Challenges & Restraints -
This section outlines the key factors shaping the growth trajectory of the High-performance Liquid Chromatography (HPLC) market:

Key Growth Drivers -
► Rising demand for high-precision and high-throughput analytical methods in pharmaceuticals and biotechnology
► Increasing investment in drug discovery, biologics development, and metabolomics research
► Stringent regulatory requirements for pharmaceutical, food, and environmental testing
► Expanding downstream applications in food additives, cosmetics, and environmental toxin analysis
► Growth of precision medicine and pharmacokinetic studies requiring advanced analytical instrumentation

Restraints & Challenges -
► High initial equipment costs and ongoing maintenance expenses
► Complexity of operation and need for skilled technical professionals
► Limited accessibility of advanced HPLC systems in emerging and low-income regions
► Risk of partial substitution by newer techniques such as UPLC in select applications

Upstream and Downstream -

Upstream, the HPLC industry relies on precision mechanical components, high-grade columns, detectors, pumps, and advanced electronic and software systems supplied by specialized instrumentation and component manufacturers.

Downstream, HPLC systems are widely used in pharmaceutical manufacturing, biotechnology research, contract research organizations (CROs), academic laboratories, chemical analysis, and environmental testing facilities. The growing diversification of downstream demand-from traditional drug testing to personalized medicine and biologics-continues to expand the application base for HPLC technologies.

Major Company Included: -
► Agilent
► Waters
► Shimadzu
► Thermo Fisher
► PerkinElmer
► Hitachi
► Jasco
► Knauer
► Bekman
► YoungLin
► GBC
► Gilson

Market Segmentation -
By Type -
► UVS
► FD
► RID
► ED
► CD

By Application -
► Pharmacy
► Biotechnology
► CROs
► Academia
► Chemicals
► Others

The report provides detailed insights into key market segments, with a strong focus on market size, CAGR, market share, and future growth potential. Each segment is thoroughly analyzed to identify demand patterns, technology adoption trends, and high-growth opportunities, enabling companies to prioritize investments and refine competitive strategies within the global HPLC market.

Regional Analysis -

✔ North America (U.S., Canada, Mexico)
✔ Europe (Germany, France, UK, Italy, etc.)
✔ Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
✔ South America (Brazil, etc.)
✔ Middle East and Africa (Turkey, GCC Countries, Africa, etc.)

Europe and the United States together account for a dominant share of the global HPLC market, driven by strong pharmaceutical and research infrastructure, while Asia-Pacific continues to show growing potential due to expanding life-science research and manufacturing capabilities.

Reasons to Procure this Report: -
► Provides global, regional, and country-level HPLC market revenue analysis through 2031
► Helps stakeholders assess market share, growth forecasts, and new expansion opportunities
► Offers segmentation by type, application, and region to support product and investment planning
► Supports investors with insights into market drivers, challenges, risks, and long-term potential
► Delivers competitive intelligence, including company rankings and strategic positioning
► Enables data-driven decision-making for business planning and market entry strategies

Key Questions Answered in the Report -
► What is the current size and future growth outlook of the global HPLC market?
► Which trends are shaping the development of the HPLC industry?
► Who are the leading players and how competitive is the market landscape?
► What are the major growth opportunities and risks across regions and applications?
► How are regulatory changes and technological advancements influencing market dynamics?

Request for Pre-Order / Enquiry Link:
https://www.qyresearch.in/pre-order-inquiry/machinery-equipment-high-performance-liquid-chromatography-hplc-market-share-and-ranking-overall-sales-and-demand-forecast-2025-2031

Table of Content:

1 Market Overview
1.1 High-performance Liquid Chromatography (HPLC) Product Introduction
1.2 Global High-performance Liquid Chromatography (HPLC) Market Size Forecast
1.2.1 Global High-performance Liquid Chromatography (HPLC) Sales Value (2020-2031)
1.2.2 Global High-performance Liquid Chromatography (HPLC) Sales Volume (2020-2031)
1.2.3 Global High-performance Liquid Chromatography (HPLC) Sales Price (2020-2031)
1.3 High-performance Liquid Chromatography (HPLC) Market Trends & Drivers
1.3.1 High-performance Liquid Chromatography (HPLC) Industry Trends
1.3.2 High-performance Liquid Chromatography (HPLC) Market Drivers & Opportunity
1.3.3 High-performance Liquid Chromatography (HPLC) Market Challenges
1.3.4 High-performance Liquid Chromatography (HPLC) Market Restraints
1.4 Assumptions and Limitations
1.5 Study Objectives
1.6 Years Considered
2 Competitive Analysis by Company
2.1 Global High-performance Liquid Chromatography (HPLC) Players Revenue Ranking (2024)
2.2 Global High-performance Liquid Chromatography (HPLC) Revenue by Company (2020-2025)
2.3 Global High-performance Liquid Chromatography (HPLC) Players Sales Volume Ranking (2024)
2.4 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Company Players (2020-2025)
2.5 Global High-performance Liquid Chromatography (HPLC) Average Price by Company (2020-2025)
2.6 Key Manufacturers High-performance Liquid Chromatography (HPLC) Manufacturing Base and Headquarters
2.7 Key Manufacturers High-performance Liquid Chromatography (HPLC) Product Offered
2.8 Key Manufacturers Time to Begin Mass Production of High-performance Liquid Chromatography (HPLC)
2.9 High-performance Liquid Chromatography (HPLC) Market Competitive Analysis
2.9.1 High-performance Liquid Chromatography (HPLC) Market Concentration Rate (2020-2025)
2.9.2 Global 5 and 10 Largest Manufacturers by High-performance Liquid Chromatography (HPLC) Revenue in 2024
2.9.3 Global Top Manufacturers by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in High-performance Liquid Chromatography (HPLC) as of 2024)
2.10 Mergers & Acquisitions, Expansion
3 Segmentation by Type
3.1 Introduction by Type
3.1.1 UVS
3.1.2 FD
3.1.3 RID
3.1.4 ED
3.1.5 CD
3.2 Global High-performance Liquid Chromatography (HPLC) Sales Value by Type
3.2.1 Global High-performance Liquid Chromatography (HPLC) Sales Value by Type (2020 VS 2024 VS 2031)
3.2.2 Global High-performance Liquid Chromatography (HPLC) Sales Value, by Type (2020-2031)
3.2.3 Global High-performance Liquid Chromatography (HPLC) Sales Value, by Type (%) (2020-2031)
3.3 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Type
3.3.1 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Type (2020 VS 2024 VS 2031)
3.3.2 Global High-performance Liquid Chromatography (HPLC) Sales Volume, by Type (2020-2031)
3.3.3 Global High-performance Liquid Chromatography (HPLC) Sales Volume, by Type (%) (2020-2031)
3.4 Global High-performance Liquid Chromatography (HPLC) Average Price by Type (2020-2031)
4 Segmentation by Application
4.1 Introduction by Application
4.1.1 Pharmacy
4.1.2 Biotechnology
4.1.3 CROs
4.1.4 Academia
4.1.5 Chemicals
4.1.6 Others
4.2 Global High-performance Liquid Chromatography (HPLC) Sales Value by Application
4.2.1 Global High-performance Liquid Chromatography (HPLC) Sales Value by Application (2020 VS 2024 VS 2031)
4.2.2 Global High-performance Liquid Chromatography (HPLC) Sales Value, by Application (2020-2031)
4.2.3 Global High-performance Liquid Chromatography (HPLC) Sales Value, by Application (%) (2020-2031)
4.3 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Application
4.3.1 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Application (2020 VS 2024 VS 2031)
4.3.2 Global High-performance Liquid Chromatography (HPLC) Sales Volume, by Application (2020-2031)
4.3.3 Global High-performance Liquid Chromatography (HPLC) Sales Volume, by Application (%) (2020-2031)
4.4 Global High-performance Liquid Chromatography (HPLC) Average Price by Application (2020-2031)
5 Segmentation by Region
5.1 Global High-performance Liquid Chromatography (HPLC) Sales Value by Region
5.1.1 Global High-performance Liquid Chromatography (HPLC) Sales Value by Region: 2020 VS 2024 VS 2031
5.1.2 Global High-performance Liquid Chromatography (HPLC) Sales Value by Region (2020-2025)
5.1.3 Global High-performance Liquid Chromatography (HPLC) Sales Value by Region (2026-2031)
5.1.4 Global High-performance Liquid Chromatography (HPLC) Sales Value by Region (%), (2020-2031)
5.2 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Region
5.2.1 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Region: 2020 VS 2024 VS 2031
5.2.2 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Region (2020-2025)
5.2.3 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Region (2026-2031)
5.2.4 Global High-performance Liquid Chromatography (HPLC) Sales Volume by Region (%), (2020-2031)
5.3 Global High-performance Liquid Chromatography (HPLC) Average Price by Region (2020-2031)
5.4 North America
5.4.1 North America High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
5.4.2 North America High-performance Liquid Chromatography (HPLC) Sales Value by Country (%), 2024 VS 2031
5.5 Europe
5.5.1 Europe High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
5.5.2 Europe High-performance Liquid Chromatography (HPLC) Sales Value by Country (%), 2024 VS 2031
5.6 Asia Pacific
5.6.1 Asia Pacific High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
5.6.2 Asia Pacific High-performance Liquid Chromatography (HPLC) Sales Value by Region (%), 2024 VS 2031
5.7 South America
5.7.1 South America High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
5.7.2 South America High-performance Liquid Chromatography (HPLC) Sales Value by Country (%), 2024 VS 2031
5.8 Middle East & Africa
5.8.1 Middle East & Africa High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
5.8.2 Middle East & Africa High-performance Liquid Chromatography (HPLC) Sales Value by Country (%), 2024 VS 2031
6 Segmentation by Key Countries/Regions
6.1 Key Countries/Regions High-performance Liquid Chromatography (HPLC) Sales Value Growth Trends, 2020 VS 2024 VS 2031
6.2 Key Countries/Regions High-performance Liquid Chromatography (HPLC) Sales Value and Sales Volume
6.2.1 Key Countries/Regions High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.2.2 Key Countries/Regions High-performance Liquid Chromatography (HPLC) Sales Volume, 2020-2031
6.3 United States
6.3.1 United States High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.3.2 United States High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.3.3 United States High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
6.4 Europe
6.4.1 Europe High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.4.2 Europe High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.4.3 Europe High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
6.5 China
6.5.1 China High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.5.2 China High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.5.3 China High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
6.6 Japan
6.6.1 Japan High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.6.2 Japan High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.6.3 Japan High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
6.7 South Korea
6.7.1 South Korea High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.7.2 South Korea High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.7.3 South Korea High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
6.8 Southeast Asia
6.8.1 Southeast Asia High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.8.2 Southeast Asia High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.8.3 Southeast Asia High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
6.9 India
6.9.1 India High-performance Liquid Chromatography (HPLC) Sales Value, 2020-2031
6.9.2 India High-performance Liquid Chromatography (HPLC) Sales Value by Type (%), 2024 VS 2031
6.9.3 India High-performance Liquid Chromatography (HPLC) Sales Value by Application, 2024 VS 2031
7 Company Profiles
7.1 Agilent
7.1.1 Agilent Company Information
7.1.2 Agilent Introduction and Business Overview
7.1.3 Agilent High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.1.4 Agilent High-performance Liquid Chromatography (HPLC) Product Offerings
7.1.5 Agilent Recent Development
7.2 Waters
7.2.1 Waters Company Information
7.2.2 Waters Introduction and Business Overview
7.2.3 Waters High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.2.4 Waters High-performance Liquid Chromatography (HPLC) Product Offerings
7.2.5 Waters Recent Development
7.3 Shimadzu
7.3.1 Shimadzu Company Information
7.3.2 Shimadzu Introduction and Business Overview
7.3.3 Shimadzu High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.3.4 Shimadzu High-performance Liquid Chromatography (HPLC) Product Offerings
7.3.5 Shimadzu Recent Development
7.4 Thermo Fisher
7.4.1 Thermo Fisher Company Information
7.4.2 Thermo Fisher Introduction and Business Overview
7.4.3 Thermo Fisher High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.4.4 Thermo Fisher High-performance Liquid Chromatography (HPLC) Product Offerings
7.4.5 Thermo Fisher Recent Development
7.5 PerkinElmer
7.5.1 PerkinElmer Company Information
7.5.2 PerkinElmer Introduction and Business Overview
7.5.3 PerkinElmer High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.5.4 PerkinElmer High-performance Liquid Chromatography (HPLC) Product Offerings
7.5.5 PerkinElmer Recent Development
7.6 Hitachi
7.6.1 Hitachi Company Information
7.6.2 Hitachi Introduction and Business Overview
7.6.3 Hitachi High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.6.4 Hitachi High-performance Liquid Chromatography (HPLC) Product Offerings
7.6.5 Hitachi Recent Development
7.7 Jasco
7.7.1 Jasco Company Information
7.7.2 Jasco Introduction and Business Overview
7.7.3 Jasco High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.7.4 Jasco High-performance Liquid Chromatography (HPLC) Product Offerings
7.7.5 Jasco Recent Development
7.8 Knauer
7.8.1 Knauer Company Information
7.8.2 Knauer Introduction and Business Overview
7.8.3 Knauer High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.8.4 Knauer High-performance Liquid Chromatography (HPLC) Product Offerings
7.8.5 Knauer Recent Development
7.9 Bekman
7.9.1 Bekman Company Information
7.9.2 Bekman Introduction and Business Overview
7.9.3 Bekman High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.9.4 Bekman High-performance Liquid Chromatography (HPLC) Product Offerings
7.9.5 Bekman Recent Development
7.10 YoungLin
7.10.1 YoungLin Company Information
7.10.2 YoungLin Introduction and Business Overview
7.10.3 YoungLin High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.10.4 YoungLin High-performance Liquid Chromatography (HPLC) Product Offerings
7.10.5 YoungLin Recent Development
7.11 GBC
7.11.1 GBC Company Information
7.11.2 GBC Introduction and Business Overview
7.11.3 GBC High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.11.4 GBC High-performance Liquid Chromatography (HPLC) Product Offerings
7.11.5 GBC Recent Development
7.12 Gilson
7.12.1 Gilson Company Information
7.12.2 Gilson Introduction and Business Overview
7.12.3 Gilson High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
7.12.4 Gilson High-performance Liquid Chromatography (HPLC) Product Offerings
7.12.5 Gilson Recent Development
8 Industry Chain Analysis
8.1 High-performance Liquid Chromatography (HPLC) Industrial Chain
8.2 High-performance Liquid Chromatography (HPLC) Upstream Analysis
8.2.1 Key Raw Materials
8.2.2 Raw Materials Key Suppliers
8.2.3 Manufacturing Cost Structure
8.3 Midstream Analysis
8.4 Downstream Analysis (Customers Analysis)
8.5 Sales Model and Sales Channels
8.5.1 High-performance Liquid Chromatography (HPLC) Sales Model
8.5.2 Sales Channel
8.5.3 High-performance Liquid Chromatography (HPLC) Distributors
9 Research Findings and Conclusion
10 Appendix
10.1 Research Methodology
10.1.1 Methodology/Research Approach
10.1.1.1 Research Programs/Design
10.1.1.2 Market Size Estimation
10.1.1.3 Market Breakdown and Data Triangulation
10.1.2 Data Source
10.1.2.1 Secondary Sources
10.1.2.2 Primary Sources
10.2 Author Details
10.3 Disclaimer

QY Research PVT. LTD.
315 Work Avenue,
Raheja Woods,
6th Floor, Kalyani Nagar,
Yervada, Pune - 411060,
Maharashtra, India
India: (O) +91 866 998 6909
USA: (O) +1 626 295 2442
Email: hitesh@qyresearch.com
Web: www.qyresearch.in

About Us -

QY Research was established in 2007 and has grown into a trusted global market research and consulting firm. Serving clients across more than 80 countries and multiple industries-from life sciences and healthcare to chemicals and advanced manufacturing-QY Research has delivered data-driven insights to over 50,000 satisfied clients. Through rigorous research methodologies and customized analytical solutions, the firm remains committed to supporting strategic decision-making and sustainable business growth worldwide.

This release was published on openPR.