Antidepressant Drugs Market is expected to reach US$ 20.6 billion by 2031 | Major players - Eli Lilly and Company, GlaxoSmithKline Plc., LGM Pharma LLC, Apotex Inc.

Market Size and Growth:

The Global Antidepressant Drugs Market size reached US$ 14.3 billion in 2022 and is expected to reach US$ 20.6 billion by 2031, growing with a CAGR of 5.56% during the forecast period 2024-2031.

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The Antidepressant Drugs Market comprises medications designed to treat depression, anxiety, and related mood disorders by regulating neurotransmitters in the brain. It includes selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclics, and atypical antidepressants. Rising mental health awareness, increasing prevalence of mood disorders, and advances in drug formulations drive market growth globally.

Recent Key Developments of United States:

✅ In December 2025, the FDA approved the first at-home brain stimulation device by Flow Neuroscience for treating depression, marking a non-drug innovation in accessible mental health therapy.

✅ In November 2025, the FDA approved CAPLYTA (lumateperone) from Johnson & Johnson as an adjunctive therapy with antidepressants for major depressive disorder (MDD) in adults, based on positive Phase 3 trials showing significant symptom improvement.

✅ In October 2025, the FDA expanded approval for Teva's UZEDY (risperidone extended-release injectable) for subcutaneous use as monotherapy or adjunctive therapy for bipolar I disorder in adults, addressing manic and depressive episodes.

Recent Key Developments of Europe:

✅ In December 2025, the EMA's CHMP issued a positive opinion in May 2025 (noted in updates) for Janssen's Spravato (esketamine nasal spray) for major depressive disorder, following US approval and emphasizing new mechanisms after two decades.

✅ In October-December 2025, EMA CHMP meetings recommended no new antidepressant drugs but advanced guidelines for depression treatments, including relapse prevention studies and cognitive function claims, influencing future EU approvals.

List of the Key Players in the Antidepressant Drugs Market:

Eli Lilly and Company
GlaxoSmithKline Plc.
LGM Pharma LLC
Apotex Inc.
Zheijiang Huahai Pharmaceutical Co. Ltd.
AstraZeneca Plc.
Takeda Pharmaceutical Co. Ltd
Pfizer Inc.
Aurobindo Pharma Limited
Merck KGaA

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This Report Covers:

✔ Go-to-market Strategy.

✔ Neutral perspective on the market performance.

✔Development trends, competitive landscape analysis, supply side analysis, demand side analysis, year-on-year growth, competitive benchmarking, vendor identification, and other significant analysis, as well as development status.

✔Customized regional/country reports as per request and country level analysis.

✔ Potential & niche segments and regions exhibiting promising growth covered.

✔ Analysis of Market Size (historical and forecast), Total Addressable Market (TAM), Serviceable Available Market (SAM), Serviceable Obtainable Market (SOM), Market Growth, Technological Trends, Market Share, Market Dynamics, Competitive Landscape and Major Players (Innovators, Start-ups, Laggard, and Pioneer).

Segments Covered in the Antidepressant Drugs Market:

By Drug Class: Monoamine oxidase inhibitors, Norepinephrine-Dopamine Reuptake Inhibitor, Serotonin-norepinephrine reuptake inhibitors, Selective serotonin reuptake inhibitors, Tricyclic antidepressants.

By Depression Disorder: Major depressive disorder, Obsessive-compulsive disorder, Generalized anxiety disorder, Panic disorder and Others.

By Distribution Channel: Hospital Pharmacy, Retail Pharmacy, Online Pharmacy.

Regional Analysis:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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Chapter Outline

⏩ Market Overview: It contains five chapters, as well as information about the research scope, major manufacturers covered, market segments, Antidepressant Drugs market segments, study objectives, and years considered.

⏩ Market Landscape: The competition in the Global Antidepressant Drugs Market is evaluated here in terms of value, turnover, revenues, and market share by organization, as well as market rate, competitive landscape, and recent developments, transaction, growth, sale, and market shares of top companies.

⏩ Companies Profiles: The Global Antidepressant Drugs market's leading players are studied based on sales, main products, gross profit margin, revenue, price, and growth production.

⏩ Market Outlook by Region: The report goes through gross margin, sales, income, supply, market share, CAGR, and market size by region in this segment. North America, Europe, Asia Pacific, Middle East & Africa, and South America are among the regions and countries studied in depth in this study.

⏩ Market Segments: It contains the deep research study which interprets how different end-user/application/type segments contribute to the Antidepressant Drugs Market.

⏩ Market Forecast: Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.

⏩ Research Findings: This section of the report showcases the findings and analysis of the report.

⏩ Conclusion: This portion of the report is the last section of the report where the conclusion of the research study is provided.

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