Single-use Bioprocessing Probes and Sensors Market to Grow at 13.9% CAGR by 2031 | North America Leads with 40% Share | Key Players: Pfizer, Wego Pharmaceuticals, Hamilton Company, Thermo Fisher, Honeywell, GE Healthcare, Polestar Technologies

The Single-use Bioprocessing Probes and Sensors Market is projected to grow at a robust CAGR of 13.9% during the forecast period 2024-2031. These probes and sensors are critical components in single-use bioreactors, enabling real-time monitoring and control of bioprocess parameters such as pH, dissolved oxygen, temperature, and conductivity. The market growth is driven by increasing adoption of single-use technologies in the biopharmaceutical industry, rising demand for flexible and contamination-free production, and advancements in sensor accuracy and integration with automated systems. Additionally, the shift toward biologics and personalized medicines is accelerating the demand for efficient, disposable bioprocessing solutions that reduce downtime, cleaning requirements, and cross-contamination risks.

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Recent Developments:

✅ October 2025: A leading bioprocessing instrumentation company launched a new suite of single‐use pH and dissolved oxygen sensors optimized for high‐throughput cell culture platforms, offering improved signal stability and reduced calibration needs.

✅ August 2025: A major life sciences firm introduced AI‐assisted sensor diagnostics that predict probe drift and recommend in‐process calibration timing, enhancing real‐time process control and reducing batch failures.

✅ June 2025: A global biopharmaceutical manufacturer announced the adoption of next‐generation single‐use conductivity sensors integrated with digital twins to optimize nutrient feed strategies in mammalian cell culture production.

✅ April 2025: A sensor technology provider expanded its product portfolio with novel optical single‐use sensors for monitoring key metabolites (e.g., glucose and lactate) in single‐use bioreactors, enabling deeper process insight without compromising sterility.

Mergers & Acquisitions:

✅ November 2025: A leading life sciences instrumentation company acquired a single‐use sensor technology specialist, strengthening its portfolio of disposable probes and enhancing its market position in bioprocess monitoring.

✅ August 2025: A major bioprocess analytics provider completed the acquisition of a bioreactor probe developer with novel optical sensing technology for improved metabolite and pH measurement in single‐use systems.

✅ June 2025: A global biotech tools supplier acquired a start‐up focused on wireless, RFID‐enabled single‐use sensors to expand its digital and connectivity offerings in disposable bioprocessing hardware.

✅ March 2025: A multinational biopharma company merged its cell culture analytics division with a niche single‐use probe manufacturer to accelerate integrated sensor adoption across its contract development and manufacturing operations.

✅ January 2025: A contract manufacturing organization (CMO) partnered through acquisition with a single‐use automation and control solutions firm, enabling tighter integration of sensors with process control software for advanced bioreactor automation.

Key Players:

• Pfizer - Major pharmaceutical company leveraging single-use probes in biopharmaceutical R&D and production.

• Wego Pharmaceuticals - Active in bioprocess development and single-use sensor integration.

• Amgen - Utilizes advanced disposable bioprocessing sensors for large-scale biologics manufacturing.

• AbbVie - Invests in single-use sensor technologies to enhance bioprocess efficiency and monitoring.

• Parker Hannifin Corporation - Provides fluid control and sensing solutions tailored for disposable bioprocessing systems.

• Hamilton Company - Supplies precision single-use probes and sensor systems for bioprocess analytics.

• Thermo Fisher Scientific, Inc. - Offers comprehensive single-use bioprocessing sensor solutions and analytical instrumentation.

• Sartorius Stedim Biotech S.A. - Focuses on bioreactor sensors, probes, and automation for single-use applications.

• Honeywell International, Inc. - Supplies process control solutions, including sensors for disposable bioprocessing setups.

• Eppendorf AG - Develops single-use probes for pH, dissolved oxygen, and temperature monitoring in bioreactors.

• G.E. Healthcare - Offers single-use sensor systems integrated with its bioprocessing equipment.

• Broadley-James - Specializes in single-use probes for pH, DO, and other critical bioprocess parameters.

• Shenzhen Tangreat Technology Co., Ltd. - Provides disposable sensor solutions for biopharma and cell therapy applications.

• Tespro Technology Co., Ltd. - Manufacturer of single-use probes and sensor technologies for R&D and industrial bioprocessing.

• Polestar Technologies, Inc. - Supplies advanced disposable sensors for monitoring critical parameters in bioreactors.

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Market Segmentation:

➥By product type, the market includes pH sensors, oxygen sensors, pressure sensors, temperature sensors, conductivity sensors, flow meters and sensors, and other specialized single-use probes. These products are critical for real-time monitoring of key parameters in bioprocessing operations, ensuring optimal growth conditions, process efficiency, and product quality.

➥By workflow, the market is categorized into upstream and downstream processes. In the upstream segment, single-use sensors are used extensively in bioreactors for monitoring pH, dissolved oxygen, and temperature to maintain ideal cell culture conditions. In downstream processing, these sensors help track pressure, flow, and conductivity to ensure proper purification, filtration, and formulation of biologics.

➥By end-user, the market serves biopharmaceutical manufacturers, the broader pharmaceutical industry, and academic research institutions. Biopharmaceutical manufacturers are the largest adopters, integrating single-use sensors to enhance operational efficiency and comply with regulatory standards. Pharmaceutical companies leverage these sensors for process development, while academic and research institutions use them for experimental workflows, preclinical trials, and technology development.

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Market Dynamics:

The growth of the single-use bioprocessing probes and sensors market is primarily driven by the rising adoption of single-use technology to address global drug shortages, coupled with the increasing prevalence of chronic diseases and the aging population. Conditions such as diabetes, obesity, cancer, and arthritis have heightened the demand for faster, more efficient, and cost-effective manufacturing solutions in the biopharmaceutical sector. Single-use bioprocessing sensors offer numerous advantages, including cost-effectiveness, reduced contamination risk, and simplified monitoring processes, making them attractive for biotechnology and pharmaceutical companies.

The deployment of single-use systems enhances productivity by eliminating the need for sterilization, reducing complexity in automation, and lowering manufacturing costs. Additionally, the flexibility of single-use bioreactors allows for multi-drug production within the same facility, optimizing floor space and minimizing time spent on preparation, setup, validation, and documentation. These systems are particularly suited for rapid manufacturing requirements, addressing the urgent need for timely production of critical therapeutics.

However, environmental concerns may restrain market growth. Safe disposal of single-use materials, technical challenges, and the overall carbon footprint of disposable components are emerging considerations for manufacturers. The environmental impact, including liquid and solid waste management, energy consumption, and life-cycle analysis of materials, has increasingly come under scrutiny. Despite these challenges, ongoing innovations in sensor technology and the development of environmentally sustainable single-use solutions are expected to create new opportunities in the market, ensuring continued expansion in the bioprocessing probes and sensors sector.

Regional Insights:

orth America dominates the single-use bioprocessing probes and sensors market, holding approximately 40% share (USD 2.61 billion in 2024). The region's leadership is driven by the presence of major biopharmaceutical manufacturers, advanced R&D infrastructure, and early adoption of single-use technologies. The U.S. and Canada have robust regulatory support for biopharmaceutical innovation, enabling widespread deployment of single-use bioprocessing systems for both clinical and commercial production.

Europe accounts for around 25% share (USD 1.63 billion in 2024), supported by well-established biotechnology hubs in Germany, France, Switzerland, and the UK. Investments in modern manufacturing facilities, coupled with strong regulatory frameworks and sustainability initiatives, are accelerating adoption of single-use probes and sensors across biopharmaceutical operations.

Asia-Pacific is the fastest-growing region, representing 28% share (USD 1.83 billion in 2024), with a projected CAGR exceeding 15% during 2025-2031. Rapid growth in biologics manufacturing, increasing R&D investments, and expansion of contract manufacturing organizations (CMOs) in countries like China, India, and Japan are driving demand. Government initiatives supporting biotechnology and healthcare infrastructure further bolster market growth in this region.

Latin America, Middle East & Africa (LAMEA) contribute the remaining 7% share (USD 0.46 billion in 2024). Market growth in these regions is supported by the gradual expansion of biopharmaceutical manufacturing facilities, increasing awareness of advanced single-use technologies, and rising investments in research and clinical production capabilities, particularly in Brazil, Mexico, South Africa, and the UAE.

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