Press release
United States Attention Deficit Hyperactivity Disorder (ADHD) Market 2033 | Growth Drivers, Key Players & Investment Opportunities
Market Size and GrowthAttention Deficit Hyperactivity Disorder (ADHD) Market size reached US$ 16.23 billion in 2024 and is expected to reach US$ 27.04 billion by 2033, growing at a CAGR of 5.9% during the forecast period 2025-2033.
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Key Development:
United States: Recent ADHD Developments
✅ In November 2025, Otsuka Pharmaceutical submitted a New Drug Application to the U.S. Food and Drug Administration for centanafadine, a novel non-stimulant ADHD therapy targeting norepinephrine, dopamine, and serotonin reuptake. The submission is supported by multiple Phase 3 clinical trials across pediatric, adolescent, and adult populations. This marks a significant step toward expanding non-stimulant treatment options in the U.S.
✅ In November 2025, clinical and pharmaceutical stakeholders in the U.S. highlighted centanafadine's potential to address core ADHD symptoms through a differentiated mechanism of action. The development reflects growing industry momentum toward alternatives beyond traditional stimulant-based therapies. It underscores continued innovation in neuropsychiatric drug pipelines.
✅ In October 2025, U.S. healthcare and life-sciences companies increased focus on next-generation ADHD therapeutics, particularly late-stage non-stimulant candidates advancing toward regulatory milestones. Industry discussions emphasized improving long-term safety, tolerability, and treatment adherence. This trend signals a shift in ADHD drug development priorities.
✅ In September 2025, U.S. research and clinical communities reinforced efforts to integrate pharmacological and adjunctive therapeutic approaches for ADHD management. Ongoing developments emphasized improved diagnosis, patient-centric treatment models, and innovation in behavioral and digital support tools. These initiatives aim to enhance overall ADHD care delivery.
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Japan: Recent ADHD Developments
✅ In December 2025, Shionogi & Co. received approval from Japan's Ministry of Health, Labour and Welfare for EndeavorRide, a prescription digital therapeutic for pediatric ADHD. The game-based therapy demonstrated improvements in attention and impulse control through clinical evaluation. This approval marks Japan's first authorized digital therapeutic for ADHD.
✅ In December 2025, the launch of EndeavorRide expanded Japan's ADHD treatment landscape by introducing a non-pharmacological, technology-driven option. The digital therapy is positioned as an adjunct to existing medical and behavioral interventions. It reflects Japan's growing acceptance of software-based medical treatments.
✅ In November 2025, Japan's healthcare ecosystem accelerated interest in digital therapeutics and software-as-a-medical-device (SaMD) solutions for neurodevelopmental disorders, including ADHD. Regulatory frameworks continued to support innovation in digital mental health technologies. This shift is enabling faster clinical adoption of novel ADHD care tools.
✅ In October 2025, Japanese clinical and research institutions emphasized localized development of digital and data-driven ADHD interventions. Efforts focused on improving treatment accessibility, personalization, and early-stage symptom management. These initiatives align with Japan's broader strategy to modernize mental-health care delivery.
Key Players:
=> Pfizer Inc., Takeda Pharmaceutical, Novartis AG, Eli Lilly and Company, Lupin, Mallinckrodt, Hisamitsu Pharmaceutical Co., Inc., Camber Pharmaceuticals, Inc., Collegium Pharmaceutical, Inc., and Supernus Pharmaceuticals, Inc., among others.
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Key Segments:
By Type
Combined Presentation dominates the market with 45% share, driven by its high prevalence among diagnosed ADHD patients and the need for comprehensive treatment addressing both inattentive and hyperactive-impulsive symptoms. Predominantly Inattentive Presentation accounts for 35%, supported by increasing diagnosis rates among adolescents and adults and growing awareness of attention-related cognitive disorders. Predominantly Hyperactive/Impulsive Presentation holds 20%, driven by early diagnosis in pediatric populations and rising adoption of behavioral and pharmacological interventions.
By Drug Type
Stimulants lead the market with 65% share, attributed to their proven efficacy, rapid onset of action, and widespread prescription of medications such as methylphenidate and amphetamines. Non-stimulants account for 35%, supported by growing preference for alternatives with lower abuse potential, longer duration of action, and suitability for patients with comorbid conditions.
By Age Group
Pediatric segment holds the largest share at 50%, driven by early diagnosis, school-based screening programs, and increasing parental awareness of ADHD symptoms. Adults account for 40%, supported by rising recognition of adult ADHD, workplace performance concerns, and improved diagnostic criteria. Geriatrics represent 10%, driven by growing awareness of late-life ADHD diagnosis and increasing focus on cognitive health in aging populations.
By Region
North America - 38% Share
North America leads the market with 38%, driven by high diagnosis rates, strong reimbursement frameworks, advanced healthcare infrastructure, and widespread availability of branded and generic ADHD medications in the U.S. and Canada.
Europe - 27% Share
Europe accounts for 27%, supported by increasing awareness of ADHD, expanding access to mental health services, and favorable regulatory approvals across countries such as Germany, the U.K., France, and Italy.
Asia-Pacific - 20% Share
Asia-Pacific holds 20%, fueled by rising mental health awareness, improving diagnostic capabilities, growing pediatric population, and increasing access to ADHD therapies in China, Japan, India, and South Korea.
South America - 9% Share
South America represents 9%, driven by improving healthcare access, growing awareness of neurodevelopmental disorders, and expanding pharmaceutical distribution networks in Brazil and Argentina.
Middle East & Africa - 6% Share
Middle East & Africa account for 6%, supported by gradual improvement in mental health infrastructure, increasing government initiatives, and rising awareness of ADHD diagnosis and treatment in urban regions.
FAQ
What is the current size of the Attention Deficit Hyperactivity Disorder (ADHD) Market?
A: In 2024, the Attention Deficit Hyperactivity Disorder (ADHD) Market was valued at US$ 16.23 billion, reflecting its strong industry presence.
Q2: How large is the Attention Deficit Hyperactivity Disorder (ADHD) Market expected to be by 2033?
A: By 2033, industry forecasts suggest the Attention Deficit Hyperactivity Disorder (ADHD) Market will grow to around US$ 27.04 billion , demonstrating significant expansion.
Q3: What is the growth rate of the Attention Deficit Hyperactivity Disorder (ADHD) Market?
A: The market is projected to expand at a compound annual growth rate (CAGR) of 5.9% during the forecast period from 2025 to 2033.
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