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Top Players and Market Competition in the Small Molecule CMO/CDMO Industry

12-17-2025 10:32 AM CET | Health & Medicine

Press release from: The Business Research Company

Small Molecule CMO/CDMO Market

Small Molecule CMO/CDMO Market

The small molecule CMO/CDMO market is positioned for significant expansion over the coming years, driven by evolving pharmaceutical needs and technological advancements. This sector is witnessing increasing demand as companies seek greater flexibility, compliance, and innovation in drug manufacturing and development. Below, we explore the market's size projections, key players, notable trends, and segmentation details.

Projected Market Size and Growth of the Small Molecule CMO/CDMO Market
The small molecule CMO/CDMO market is anticipated to reach a valuation of $72.9 billion by 2029, growing at a compound annual growth rate (CAGR) of 7.6%. Several factors contribute to this upward trajectory, including the surge in drug development pipelines, the globalization of pharmaceutical manufacturing, the rising demand for adaptable production processes, and the increasing importance of meeting regulatory standards. Additionally, the convergence between biopharmaceutical sectors supports this expansion. Emerging trends that are expected to influence the market during this period include the adoption of sustainable and eco-friendly manufacturing methods, enhanced collaboration and partnership models, growth in personalized medicine and niche therapies, expansion of virtual and virtual-to-reality companies, incorporation of digital technologies, and the ability to rapidly respond to changing needs.

Download a free sample of the small molecule cmo/cdmo market report:
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Top Companies Leading the Small Molecule CMO/CDMO Market
The competitive landscape of the small molecule CMO/CDMO market is shaped by a number of prominent players. These include Patheon NV (Thermo Fisher Scientific), GlaxoSmithKline, Johnson Matthey PLC, Lonza Group Ltd., WuXi AppTec, Catalent Inc., Aurobindo Pharma, Fareva, Aesica Pharmaceuticals Limited, Siegfried holdings AG, Recipharm AB, Jubilant Life Sciences Limited, Almac Group, Piramal Pharma Solutions, Oxford Chemicals Inc., Syngene International Limited, Novasep, Pfizer CentreOne, GVK Biosciences, ChemPartner, Avid Bioservices Inc., Dishman Carbogen Amcis Ltd., ProChem Inc., and Metrics Contract Services.

In a recent development, March 2023 saw Catalent Inc., a US-based pharmaceutical firm, partnering with Grünenthal GmbH, headquartered in Germany. This collaboration aims to accelerate clinical development timelines for an orally administered small molecule from Grünenthal's pipeline, enhance its bioavailability, and shorten the Phase 1 development stage. Grünenthal GmbH is known for its strategic partnerships and agreements with various contract development and manufacturing organizations.

View the full small molecule cmo/cdmo market report:
https://www.thebusinessresearchcompany.com/report/small-molecule-cmo-or-cdmo-global-market-report

Current Trends Shaping the Small Molecule CMO/CDMO Market
Leading companies are increasingly investing in cutting-edge technologies to improve their CDMO services. One notable example is the deployment of advanced small-molecule platforms designed to enhance the development, production, and efficiency of pharmaceutical compounds. In June 2023, Porton Pharma Solutions Ltd., based in China, launched a state-of-the-art small-molecule platform in Shanghai, setting a new standard within the CDMO space. This platform integrates innovative technologies and comprehensive methodologies, offering end-to-end solutions, operational flexibility, and digital transformation capabilities that cover the entire lifecycle of small molecule drugs.

Additional Market Trends Influencing Growth
The movement towards more sustainable manufacturing practices is gaining traction, reflecting growing environmental concerns within the pharmaceutical industry. Alongside this, there is a surge in partnerships and collaborative efforts among companies, which help spread expertise and resources. Personalized medicine and niche therapies are also becoming more prominent, allowing for targeted treatment approaches that demand specialized manufacturing capabilities. Furthermore, the rise of virtual and hybrid virtual-to-reality companies is reshaping operational models, while digital technologies are enhancing manufacturing speed and precision.

Essential Segments of the Small Molecule CMO/CDMO Market
The global small molecule CMO/CDMO market is categorized across several key segments:

1) Product Type:
- Small Molecule Drug Product
- Small Molecule API (Active Pharmaceutical Ingredient)

2) Stage of Development:
- Clinical
- Commercial
- Preclinical

3) Therapeutic Areas:
- Oncology
- Neurology
- Infectious Disease
- Cardiovascular Disease
- Respiratory Disorders
- Metabolic Disorders
- Other Therapeutic Areas

4) Applications:
- Cardiovascular
- Oncology
- Diabetes
- Immunological Disorders

Detailed subsegments further break down the market:

- For Small Molecule Drug Products, the forms include solid dosage forms such as tablets and capsules, liquid dosage forms like injectables and solutions, and topical dosage forms.
- For Small Molecule APIs, categories include generic APIs, branded APIs, and custom synthesis APIs.

These classifications provide a comprehensive framework for understanding the scope and diversity of the small molecule CMO/CDMO market.

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With over 17500+ reports from 27 industries covering 60+ geographies, The Business Research Company has built a reputation for offering comprehensive, data-rich research and insights. Armed with 1,500,000 datasets, the optimistic contribution of in-depth secondary research, and unique insights from industry leaders, you can get the information you need to stay ahead.Our flagship product, the Global Market Model (GMM), is a premier market intelligence platform delivering comprehensive and updated forecasts to support informed decision-making.

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