Press release
Overview of Segmentation, Market Dynamics, and Competitive Landscape in the Celiac Disease Treatment Market
Celiac Disease Treatment
Forecasted Expansion of the Celiac Disease Treatment Market Size Through 2029
The celiac disease treatment market is projected to grow robustly, reaching a value of $0.94 billion by 2029 with a compound annual growth rate (CAGR) of 9.3%. This upward trajectory is driven by several critical factors including the increasing global prevalence of celiac disease, higher rates of diagnosis and awareness, ongoing clinical trials aimed at developing novel therapies, and a rising preference for gluten-free products. Additionally, supportive regulatory policies for orphan diseases and growing healthcare investments are fueling this market's expansion. Significant trends expected to influence this market involve the adoption of innovative non-dietary therapies, progress in enzyme supplement formulations, personalized medicine approaches, advances in peptide-based immunotherapies, enhanced diagnostic technologies, and clinical trial improvements.
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Important Factors Contributing to Market Growth
A key factor boosting the celiac disease treatment market is the rising prevalence of the condition globally, which leads to greater demand for effective treatment options. Increased awareness and better diagnostic tools also contribute to more patients being identified and treated.
In addition, regulatory support for orphan diseases encourages investment in research and development, while healthcare spending on innovative treatments continues to grow. These elements collectively enhance the market's growth prospects over the forecast period.
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Top Companies Leading the Celiac Disease Treatment Market
Several prominent pharmaceutical and biotechnology companies dominate the competitive landscape of the celiac disease treatment market. These include Pfizer Inc., Johnson And Johnson, F. Hoffmann-La Roche Ltd., Merck And Co. Inc., Sanofi S.A., Novartis AG, Takeda Pharmaceuticals Company Ltd., Amgen Inc., General Mills Inc., Viatris Inc., Teva Pharmaceutical Inc., Nestlé Health Science, Hikma Pharmaceuticals PLC, Amneal Pharmaceuticals LLC, Zydus Pharmaceuticals Inc., Glenmark Pharmaceuticals Company Ltd., West-Ward Pharmaceuticals Company Ltd, Innovate Biopharmaceutical, Acto Biosciences, and ImmunogenX.
Collaborative Developments Advancing Treatment Options
In October 2022, Takeda Pharmaceutical Company Limited, headquartered in Japan, formed a partnership with Zedira GmbH and Dr. Falk Pharma to develop an innovative oral therapy called TAK-227 (ZED1227). This treatment targets intestinal repair and inflammation, offering a promising approach for managing celiac disease. Zedira GmbH is a German biotechnology firm specializing in treatments for celiac disease and related transglutaminase conditions, while Dr. Falk Pharma, also based in Germany, focuses on gastrointestinal disorder medications.
Emerging Focus on Oral Therapies in Celiac Disease Treatment
Leading companies in the celiac disease arena are increasingly concentrating on developing oral therapies, particularly small molecule drugs. These therapies aim to provide targeted relief by blocking immune reactions to gluten, which helps improve treatment adherence and offers alternatives to strict gluten-free diets. Small molecule therapies are designed to enter cells easily and modulate disease-causing proteins or enzymes.
For example, in February 2025, the US biotech company Immunic Inc. introduced IMU-856, a small molecule that elevates endogenous glucagon-like peptide-1 (GLP-1) levels. This action improves intestinal barrier function in patients with celiac disease, enhances nutrient absorption, and alleviates symptoms without suppressing immune responses.
Detailed Breakdown of the Celiac Disease Treatment Market Segmentation
This market is segmented based on treatment type, enzyme type, diagnosis method, and distribution channel, providing a comprehensive view of patient management approaches.
By Treatment Type:
- Vitamins and Minerals
- Gluten Degrading Enzymes
- Symptomatic Treatment
- Other Treatments
By Enzyme Type:
- Distension
- Diarrhoea
- Anorexia
- Bloating
- Gas
- Fatigue
By Diagnosis Method:
- Serological Tests
- Genetic Testing
- Biopsy
By Distribution Channel:
- Hospitals
- Research Centres
- Clinics
- Other Distribution Channels
Further subcategories under vitamins and minerals include iron supplements, calcium supplements, vitamin D, vitamin B12, and multivitamins. Gluten-degrading enzymes are divided into endopeptidases, exopeptidases, and combination enzyme formulations. Symptomatic treatments cover antidiarrheal medications, antidepressants, anti-inflammatory drugs, and immunosuppressive agents. Other treatments include probiotics, immunotherapy, stem cell therapy, and experimental therapies.
This detailed segmentation highlights the variety of approaches being researched and used to manage celiac disease, reflecting the complexity and personalized nature of treatment in this field.
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