Knee Replacement Market is expected to reach US$ 16.72 billion by 2033 | Emerging key players - Aesculap Implant Systems, LLC, Medacta International SA, Corin Group.

Market Size and Growth:

The Global Knee Replacement Market size reached US$ 10.85 billion in 2024 and is expected to reach US$ 16.72 billion by 2033, growing at a CAGR of 4.8% during the forecast period 2025-2033.

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The Knee Replacement Market refers to the global industry involved in the manufacturing, distribution, and sale of knee prosthetics and related surgical devices used to treat severe knee joint damage caused by arthritis, injury, or degeneration. The market encompasses total and partial knee replacement procedures, innovative implants, surgical instruments, and post-operative care solutions, driven by aging populations, rising arthritis prevalence, and technological advancements in orthopedics.

Recent Key Developments of United States:

✅ BioPoly enrolled the first U.S. patient in its clinical trial for the BioPoly Partial Resurfacing Knee Implant in September 2025, marking a milestone toward FDA approval for a synthetic cartilage alternative to total or partial knee replacements.​

✅ In November 2025 highlighted over 600,000 annual knee replacement surgeries in the U.S., driven by osteoarthritis, aging populations, and rising demand for robotic-assisted and personalized implants.​

✅ Washington Health announced exciting advancements in knee replacement options in November 2025, addressing the nearly 1 million annual U.S. procedures with revolutionary technologies for improved outcomes.​

List of the Key Players in the Knee Replacement Market:

Zimmer Biomet Holdings, Inc
Stryker Corporation
DePuy Synthes (Johnson & Johnson)
Smith & Nephew Plc
B. Braun Melsungen AG
Medtronic Plc
MicroPort Scientific Corporation
Exactech, Inc
Conformis, Inc
DJO Global, Inc

Emerging Market Players:

Aesculap Implant Systems, LLC
Medacta International SA
Corin Group
Think Surgical, Inc

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This Report Covers:

✔ Go-to-market Strategy.

✔ Neutral perspective on the market performance.

✔Development trends, competitive landscape analysis, supply side analysis, demand side analysis, year-on-year growth, competitive benchmarking, vendor identification, and other significant analysis, as well as development status.

✔Customized regional/country reports as per request and country level analysis.

✔ Potential & niche segments and regions exhibiting promising growth covered.

✔ Analysis of Market Size (historical and forecast), Total Addressable Market (TAM), Serviceable Available Market (SAM), Serviceable Obtainable Market (SOM), Market Growth, Technological Trends, Market Share, Market Dynamics, Competitive Landscape and Major Players (Innovators, Start-ups, Laggard, and Pioneer).

Segments Covered in the Knee Replacement Market:

By Procedure Type: Total Knee Replacement, Partial Knee Replacement, Revision Knee Replacement.

By Implant Type: Fixed-Bearing Implants, Mobile-Bearing Implants, Medial Pivot Implants, Customized Implants.

By Component: Femoral Component, Tibial Component, Patellar Component.

By Fixation Type: Cemented Fixation, Cementless Fixation, Hybrid Fixation.

By End User: Hospitals, Ambulatory Surgical Centers (ASCs), Orthopedic Clinics, Rehabilitation Centers.

Regional Analysis:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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Chapter Outline

⏩ Market Overview: It contains five chapters, as well as information about the research scope, major manufacturers covered, market segments, Knee Replacement market segments, study objectives, and years considered.

⏩ Market Landscape: The competition in the Global Knee Replacement Market is evaluated here in terms of value, turnover, revenues, and market share by organization, as well as market rate, competitive landscape, and recent developments, transaction, growth, sale, and market shares of top companies.

⏩ Companies Profiles: The Global Knee Replacement market's leading players are studied based on sales, main products, gross profit margin, revenue, price, and growth production.

⏩ Market Outlook by Region: The report goes through gross margin, sales, income, supply, market share, CAGR, and market size by region in this segment. North America, Europe, Asia Pacific, Middle East & Africa, and South America are among the regions and countries studied in depth in this study.

⏩ Market Segments: It contains the deep research study which interprets how different end-user/application/type segments contribute to the Knee Replacement Market.

⏩ Market Forecast: Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.

⏩ Research Findings: This section of the report showcases the findings and analysis of the report.

⏩ Conclusion: This portion of the report is the last section of the report where the conclusion of the research study is provided.

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People Also Ask:

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◆ Which region is expected to dominate the industry during the forecast period?

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