Cancer Vaccines Industry Trends: Phase II Success, IND Approvals & Biotech Innovations Power Oncology Immunotherapy Market | Top Companies are Merck & Co., Inc., GlaxoSmithKline plc (GSK), and Dendreon Pharmaceuticals LLC

The global cancer vaccines market reached US$ 8.82 Billion in 2023, with a rise of US$ 9.27 Billion in 2024 and is expected to reach US$ 14.96 Billion by 2033, growing at a CAGR of 5.5% during the forecast period 2025-2033.

According to DataM Intelligence has published a new research report on "Cancer Vaccines Market Size 2025". The report explores comprehensive and insightful Information about various key factors like Regional Growth, Segmentation, CAGR, Business Revenue Status of Top Key Players and Drivers. The purpose of this report is to provide a telescopic view of the current market size by value and volume, opportunities, and development status.

Cancer vaccines are immunotherapies designed to prevent or treat cancer by stimulating the immune system to target tumor cells. They include preventive vaccines like HPV and therapeutic vaccines under development. These vaccines enhance immune recognition of cancer-specific antigens. Growing focus on personalized medicine accelerates research. Market growth is driven by rising cancer incidence and biotech innovation.

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➣ Recent Developments:

✅ In July 2025, Moderna reported promising Phase II results for its personalized mRNA cancer vaccine targeting melanoma recurrence. The therapy showed a significant reduction in relapse rates when combined with immunotherapy.

✅ In June 2025, BioNTech initiated Phase III trials for its neoantigen-based cancer vaccine platform, expanding indications to colorectal and pancreatic cancers.

✅ In May 2025, Gritstone Bio received FDA Fast Track designation for its tumor-specific antigen vaccine designed for lung cancer patients, accelerating regulatory review.

Latest FDA:

JCXH-211 (mRNA neoantigen vaccine): FDA IND approved post-Phase 1 (NCT05727839); expresses IL-12 for tumor targeting, distal tumor eradication.​

DOC1021 (dendritic cell vaccine): FDA orphan drug status for glioblastoma; Phase 1 recruitment complete, high safety profile.​

mRNA-4157/V940 (Moderna/Merck): Phase 3 ongoing for melanoma; 44% recurrence reduction with pembrolizumab (Phase 2b data).

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➣ Cancer Vaccines Market - Major Players

The major players in the cancer vaccines market include Merck & Co., Inc., GlaxoSmithKline plc (GSK), and Dendreon Pharmaceuticals LLC, among others.

➣ Cancer Vaccines Market - Emerging Players
The emerging players in the cancer vaccines market include Candel Therapeutics, Elicio Therapeutics, Evaxion, Imugene, Nouscom, OSE Immunotherapeutics, Scancell, and Takis, among others.

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➣ Market Segments:

By Technology: Dendritic Cells Vaccines, Anti-idiotype Vaccines, Antigen Vaccines, Whole Tumor Vaccines, DNA Vaccines

By Type: Preventive Cancer Vaccines, Treatment Cancer Vaccines.

By Disease Type: Cervical Cancer, Prostate Cancer, Others

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