Viral Vector Purification Market Overview, Key Trends, and Insights on Top Players

The viral vector purification industry is on the cusp of significant expansion, driven by advancements in technology and increasing demand across healthcare and biotechnology sectors. As gene therapies and viral vector applications continue to grow, the need for efficient and scalable purification solutions becomes more critical. This overview explores the market size, key players, emerging trends, and segmentation that define this evolving landscape.

Market Valuation and Growth Outlook for the Viral Vector Purification Market
The viral vector purification market is anticipated to experience rapid growth, reaching a valuation of $3.38 billion by 2029. This surge represents a compound annual growth rate (CAGR) of 17.9%. Factors contributing to this expansion include heightened investment in cutting-edge purification technologies, an emphasis on scalable manufacturing processes, the widening adoption of gene delivery platforms, growing utilization of viral vectors in emerging regions, and increased demand for streamlined downstream processing. Notable trends expected to influence the market during this period encompass the creation of innovative purification methods, development of single-use bioprocessing systems, progress in continuous purification workflows, the introduction of hybrid chromatography techniques, and advances in automated process monitoring.

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Key Market Players Making an Impact in Viral Vector Purification
Several prominent companies are shaping the viral vector purification space, including Merck KGaA, Thermo Fisher Scientific Inc., Lonza Group AG, FUJIFILM Diosynth Biotechnologies, Danaher Corporation, Sartorius AG, Agilent Technologies Inc., Eurofins Scientific SE, Charles River Laboratories International Inc., Bio-Rad Laboratories Inc., AGC Biologics A/S, CoJourney, Takara Bio Inc., Miltenyi Biotec B.V. & Co. KG, Oxford Biomedica PLC, Revvity Inc., Applied Biological Materials Inc. (ABM), Minapharm Pharmaceuticals, Batavia Biosciences B.V., Creative Biolabs Inc., and Andelyn Biosciences Inc.

Significant Acquisition Strengthening Market Position
In September 2025, Thermo Fisher Scientific Inc., a leading US-based life sciences and scientific instruments firm, acquired Solventum's purification and filtration division for roughly $4.0 billion. This strategic move allows Thermo Fisher to broaden its bioprocessing portfolio by incorporating Solventum's sophisticated purification and filtration technologies. The acquisition enhances the company's capabilities in delivering high-quality and efficient viral vector manufacturing solutions that span both upstream and downstream workflows. Solventum Corporation, headquartered in the US, specializes in bioprocessing filtration and purification products applicable to viral vector purification processes.

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Innovations and Trends Shaping the Viral Vector Purification Sector
Companies in this market are increasingly focusing on the development of rapid, high-throughput analytical tools to improve process efficiency, ensure vector purity, and shorten development timelines. One such technology gaining traction is macro mass photometry, which utilizes light scattering to precisely measure viral particle size and mass. This enables quick differentiation between empty and full capsids, as well as detection of degraded viral particles.

A case in point is the November 2023 launch of KaritroMP by Refeyn Ltd., a UK-based biotech firm. This macro mass photometry platform can analyze adenovirus and lentivirus vectors in just six minutes, offering semi-automated sample handling for up to 13 samples at once. It delivers consistent quality control results and detects subtle mass differences to optimize purification steps. This innovation aids viral vector producers by accelerating quality assessment and streamlining workflows, thereby saving time and resources during characterization and purification.

Comprehensive Segmentation of the Viral Vector Purification Industry
The viral vector purification market is categorized across several key segments:
1) Vector Type: Adenoviral Vectors, Lentiviral Vectors, Adeno-Associated Viral Vectors, Retroviral Vectors, and Other Vector Types
2) Product Type: Kits, Reagents, Instruments, and Services
3) Purification Techniques: Chromatography, Ultrafiltration, Precipitation, and Other Methods
4) Applications: Gene Therapy, Vaccinology, Research, and Other Uses
5) End-Users: Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Contract Research Organizations, and Other Users

Further subcategories include:
- Adenoviral Vectors: First Generation, Second Generation, Third Generation
- Lentiviral Vectors: Integrating Lentiviral Vectors, Non-Integrating Lentiviral Vectors
- Adeno-Associated Viral Vectors: Recombinant and Self-Complementary Types
- Retroviral Vectors: Gamma, Alpha, and Beta Retroviral Types

This detailed segmentation offers a thorough understanding of the viral vector purification market's structure, enabling stakeholders to identify specific areas for growth and innovation.

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