Thyroid Cancer Clinical Trial Pipeline Expands as 50+ Companies Driving Innovation in the Therapeutics | DelveInsight

DelveInsight's, "Thyroid Cancer Pipeline Insight 2025" report provides comprehensive insights about 50+ companies and 51+ pipeline drugs in Thyroid Cancer pipeline landscape. It covers the Thyroid Cancer pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Thyroid Cancer therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Download DelveInsight's comprehensive Thyroid Cancer Pipeline Report to explore emerging therapies, key Thyroid Cancer Companies, and future Thyroid Cancer treatment landscapes @ Thyroid Cancer Pipeline Outlook Report [https://www.delveinsight.com/sample-request/thyroid-cancer-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]

Key Takeaways from the Thyroid Cancer Pipeline Report

* On December 05, 2025, researchers reported encouraging results from a first-in-human evaluation of a novel targeted alpha therapy using 211At (astatine) for individuals with thyroid cancer unresponsive to conventional radioactive iodine, the current beta-emitting standard. A single administered dose demonstrated a favorable safety profile and notable disease control even in the absence of additional molecularly targeted drugs. These results were featured in the December edition of The Journal of Nuclear Medicine.
* On December 02, 2025- Novartis Pharmaceuticals conducted a study is to assess the efficacy and safety of dabrafenib in combination with trametinib for treating adult patients with locally advanced or metastatic Differentiated Thyroid Cancer (DTC) harboring the BRAFV600E mutation, who are refractory to radioactive iodine (RAI) therapy and have experienced disease progression following one or two prior VEGFR-targeted treatments.
* On December 01, 2025- Chia Tai Tianqing Pharmaceutical Group Co., Ltd . announced a study aims to demonstrate that, in subjects with locally advanced or metastatic iodine - refractory differentiated thyroid cancer who have failed previous VEGFR - targeted therapy, AL2846 can significantly prolong progression - free survival (PFS) compared with placebo.
* DelveInsight's Thyroid Cancer pipeline report depicts a robust space with 50+ active players working to develop 51+ pipeline therapies for Thyroid Cancer treatment.
* The leading Thyroid Cancer Companies such as AffyImmune Therapeutics, Suzhou Zelgen Biopharmaceuticals, Bristol-Myers Squibb, Suzhou NeuPharma, AstraZeneca, Verastem Oncology, Thryv Therapeutics, Molecular Targeting Technologies, Chimerix, Codiak BioSciences, LeadArtis, Tyra Biosciences, Roche, Sichuan Kelun-Biotech Biopharmaceutical, Advenchen Laboratories , and others.
* Promising Thyroid Cancer Therapies such as Selpercatinib, Cabozantinib, Vandetanib, E7080 Capsule, Lenvatinib (DTC Cohort), Irofulven + capecitabine, XL184, AL2846 Capsule, and others.

Access DelveInsight's in-depth Thyroid Cancer Pipeline Analysis for a closer look at promising breakthroughs @ Thyroid Cancer Clinical Trials and Studies [https://www.delveinsight.com/sample-request/thyroid-cancer-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]

The Thyroid Cancer Pipeline Report provides a disease overview, pipeline scenario, and therapeutic assessment of the key pipeline therapies in this domain. The Thyroid Cancer Pipeline Report also highlights the unmet needs with respect to the Thyroid Cancer.

Thyroid Cancer Overview

Thyroid cancer is a malignant condition that primarily arises from the follicular cells of the thyroid gland, which are responsible for producing thyroid hormones. The symptoms of thyroid cancer include a neck lump, hoarseness, difficulty swallowing, and swollen lymph nodes, though many early cases are asymptomatic. Thyroid cancer risk is influenced by a combination of genetic, environmental, and lifestyle factors. The most well-established cause is exposure to ionizing radiation, particularly during childhood, which significantly raises the likelihood of developing thyroid malignancies. Inherited genetic syndromes such as MEN2, Cowden syndrome, and familial medullary thyroid cancer also contribute to increased risk. Women are more commonly affected, possibly due to hormonal influences like estrogen. Lifestyle and environmental factors, including obesity, low iodine intake, and exposure to pollutants, may also play a key role.

Thyroid Cancer Emerging Drugs

* rhTSH: Suzhou Zelgen Biopharmaceuticals

Recombinant human TSH (rhTSH) was developed to provide TSH stimulation without the requirement for THST withdrawal and the resultant metabolic disturbance, and without the drawbacks associated with the use of bovine TSH. The drug is currently being evaluated under Phase III clinical trial for the treatment of patients with thyroid cancer.

* Nivolumab: Bristol-Myers Squibb

Nivolumab is a human immunoglobulin G4 (IgG4) monoclonal antibody that binds to the PD-1 receptor and blocks its interaction with PD-L1 and PD-L2, releasing PD-1 pathway-mediated inhibition of the immune response, including the anti-tumor immune response. The drug is currently being evaluated under Phase II clinical trial for the treatment of patients with thyroid cancer.

* RX208: Suzhou NeuPharma

RX208 is a potential "best-in-class" BRAF V600E inhibitor with a proprietary novel chemical structure that is different from other marketed BRAF inhibitors. It exhibited high bioavailability and excellent anti-tumor efficacy in preclinical studies. Early clinical data demonstrated preliminary efficacy and good safety and tolerability in patients with cancer, warranting further clinical development. The drug is currently being evaluated under Phase I/II clinical trial for the treatment of patients with thyroid cancer.

* AIC100: AffyImmune Therapeutics

AffyImmune's lead product, AIC100, is an affinity-tuned, ICAM-1 targeted, third generation CAR T cell therapy. AIC100's CAR has an affinity to ICAM-1 similar to the affinity between naturally-occurring T cells and their targets, which is much lower than most CARs used to date and reduces on-target off-tumor toxicities. AIC100 also expresses SSTR2 for real-time monitoring of CAR T cell distribution and activity. Preclinical studies demonstrate that AIC100 induces robust and enduring tumor eradication without toxicity-related relapse or fatality in various solid tumor models. Studies also suggest the potential for combination with anti-PD-1 therapies. The drug is currently being evaluated under Phase I clinical trial for the treatment of patients with Thyroid Cancer.

Get a detailed analysis of the latest innovations in the Thyroid Cancer pipeline. Explore DelveInsight's expert-driven report today! @ Thyroid Cancer Unmet Needs [https://www.delveinsight.com/sample-request/thyroid-cancer-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]

The Thyroid Cancer pipeline report provides insights into

* The report provides detailed insights about companies that are developing therapies for the treatment of Thyroid Cancer with aggregate therapies developed by each company for the same.
* It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Thyroid Cancer Treatment.
* Thyroid Cancer Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
* Thyroid Cancer Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
* Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Thyroid Cancer market.

Thyroid Cancer Companies

AffyImmune Therapeutics, Suzhou Zelgen Biopharmaceuticals, Bristol-Myers Squibb, Suzhou NeuPharma, AstraZeneca, Verastem Oncology, Thryv Therapeutics, Molecular Targeting Technologies, Chimerix, Codiak BioSciences, LeadArtis, Tyra Biosciences, Roche, Sichuan Kelun-Biotech Biopharmaceutical, Advenchen Laboratories, and others.

Thyroid Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration

* Intravenous
* Subcutaneous
* Oral
* Intramuscular

Thyroid Cancer Products have been categorized under various Molecule types such as

* Monoclonal antibody
* Small molecule
* Peptide

Download DelveInsight's latest report to gain strategic insights into upcoming Thyroid Cancer Therapies and key Thyroid Cancer Developments @ Thyroid Cancer Market Drivers and Barriers, and Future Perspectives [https://www.delveinsight.com/sample-request/thyroid-cancer-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]

Scope of the Thyroid Cancer Pipeline Report

* Coverage- Global
* Thyroid Cancer Companies- AffyImmune Therapeutics, Suzhou Zelgen Biopharmaceuticals, Bristol-Myers Squibb, Suzhou NeuPharma, AstraZeneca, Verastem Oncology, Thryv Therapeutics, Molecular Targeting Technologies, Chimerix, Codiak BioSciences, LeadArtis, Tyra Biosciences, Roche, Sichuan Kelun-Biotech Biopharmaceutical, Advenchen Laboratories, and others.
* Thyroid Cancer Therapies- Selpercatinib, Cabozantinib, Vandetanib, E7080 Capsule, Lenvatinib (DTC Cohort), Irofulven + capecitabine, XL184, AL2846 Capsule, and others.
* Thyroid Cancer Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
* Thyroid Cancer Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Which companies are leading the race in Thyroid Cancer drug development? Find out in DelveInsight's exclusive Thyroid Cancer Pipeline Report-access it now! @ Thyroid Cancer Emerging Drugs and Major Companies [https://www.delveinsight.com/sample-request/thyroid-cancer-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]

Table of Content

* Introduction
* Executive Summary
* Thyroid Cancer: Overview
* Pipeline Therapeutics
* Therapeutic Assessment
* Thyroid Cancer- DelveInsight's Analytical Perspective
* Late Stage Products (Phase III)
* rhTSH: Suzhou Zelgen Biopharmaceuticals
* Drug profiles in the detailed report.....
* Mid Stage Products (Phase II)
* Nivolumab: Bristol-Myers Squibb
* Drug profiles in the detailed report.....
* Early Stage Products (Phase I)
* AIC100:Affyimmune Therapeutics
* Drug profiles in the detailed report.....
* Preclinical and Discovery Stage Products
* Drug name: Company name
* Drug profiles in the detailed report.....
* Inactive Products
* Thyroid Cancer Key Companies
* Thyroid Cancer Key Products
* Thyroid Cancer- Unmet Needs
* Thyroid Cancer- Market Drivers and Barriers
* Thyroid Cancer- Future Perspectives and Conclusion
* Thyroid Cancer Analyst Views
* Thyroid Cancer Key Companies
* Appendix

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