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Postmenopausal Osteoporosis Market Advances as Biologics, Biosimilars, and Fracture-Prevention Strategies Gain Global Momentum

12-05-2025 12:16 PM CET | Business, Economy, Finances, Banking & Insurance

Press release from: Exactitude Consultancy

Postmenopausal Osteoporosis Market

Postmenopausal Osteoporosis Market

The Postmenopausal Osteoporosis Market is entering a new phase of innovation and expansion as the global population ages. With fragility fractures becoming a leading cause of disability in older women, healthcare systems are prioritizing preventive therapy. High-efficacy biologics, oral medications, hormone-based treatments, and new biosimilar entrants are poised to drive significant growth over the next decade.

Download Full PDF Sample Copy of Market Report @ https://exactitudeconsultancy.com/request-sample/72060

Keyword Definition
Postmenopausal osteoporosis is a chronic metabolic bone disorder caused by estrogen deficiency after menopause. This hormonal decline accelerates bone loss, leading to reduced bone mineral density and higher risk of fractures involving the spine, hip, wrist, and other vulnerable sites.

Standard therapies fall into three major categories:
• Antiresorptive agents:
Bisphosphonates (alendronate, risedronate, ibandronate, zoledronic acid), denosumab, SERMs such as raloxifene and bazedoxifene.
• Anabolic agents (bone-forming):
Teriparatide, abaloparatide, and romosozumab, which stimulate new bone growth and significantly improve bone strength.
• Hormonal therapies:
Estrogen therapy, tibolone, and combination therapies for eligible postmenopausal women.
These treatments aim to slow or reverse bone loss, increase bone density, prevent fractures, and enhance long-term mobility and quality of life.

Key Players in This Market
The competitive ecosystem includes global pharmaceutical leaders and emerging biosimilar manufacturers:
• Amgen (Prolia/Xgeva - denosumab)
• Eli Lilly (teriparatide)
• UCB and Amgen (romosozumab partnership)
• Novartis, Merck, Roche, Pfizer, AbbVie, Sanofi (bisphosphonates and hormonal therapies)
• Biocon Biologics and Dr. Reddy's Laboratories (recently launched denosumab biosimilars)
• Several generics manufacturers supplying oral bisphosphonates worldwide

Key Events in the Last Five Years
• Biologics such as denosumab and romosozumab saw growing adoption due to superior fracture risk reduction.
• Denosumab biosimilars entered major markets, signaling a shift toward cost-effective biologic therapy and increasing patient accessibility.
• Updated clinical guidelines worldwide strengthened recommendations for early assessment and treatment of high-risk postmenopausal women.
• Anabolic therapies like romosozumab demonstrated strong results in rapid BMD increases, leading to broader clinical uptake.
• Digital bone health management tools and real-world fracture prediction algorithms gained visibility, supporting earlier diagnosis and timely treatment.

Market Growth Rate (CAGR & Forecast)
The Postmenopausal Osteoporosis Market is currently valued in the multi-billion-dollar range and is projected to grow steadily through 2034 due to:
• Rapid global expansion of the elderly female population
• Rising incidence of fragility fractures
• Greater availability of biologics and biosimilars
• Expanding screening and early diagnosis initiatives
• Improved reimbursement for high-risk osteoporosis patients
Most forecasts place the market's CAGR in the high single-digit range for the next decade.

Market Segments and Growth Insights
By Therapy Class
• Antiresorptive therapies remain the largest segment, driven by bisphosphonates as first-line treatment and denosumab as a high-value biologic option.
• Anabolic therapies show the fastest growth due to strong fracture-prevention efficacy and increasing physician preference for high-risk patients.
• Hormone-based therapies maintain relevance among early postmenopausal women requiring symptomatic relief along with bone protection.

By Route of Administration
• Oral medications dominate volume due to widespread use of bisphosphonates.
• Injectable biologics and anabolics account for significant revenue share and growing adoption.

By End User
• Hospitals and specialty clinics
• Ambulatory centers and endocrinology clinics
• Retail and specialty pharmacies
• Osteoporosis management programs and women's health centers

Explore Full Report here: https://exactitudeconsultancy.com/reports/72060/postmenopausal-osteoporosis-market

Regional Outlook
• North America leads due to advanced diagnostic infrastructure, high biologic adoption, and strong awareness.
• Europe follows with structured fracture-prevention programs and widespread use of biosimilars.
• Asia-Pacific is the fastest-growing region due to rapid aging, improved healthcare access, and rising urban lifestyle risk factors.
• Latin America and Middle East/Africa are expanding gradually as awareness and treatment availability increase.

Key Market Drivers
• Rising global prevalence of osteoporosis and fragility fractures
• Increased longevity of women post-menopause
• Rapid uptake of biologics and newly launched biosimilars
• Growing focus on fracture prevention as a public health priority
• Improved screening through DEXA, AI-based fracture risk tools, and digital health platforms
• Shift toward early intervention and long-term bone health management

Conclusion
The Postmenopausal Osteoporosis Market is positioned for strong and sustained growth. With biologics, anabolic agents, and biosimilars expanding therapeutic choice-and global health systems prioritizing fracture prevention-the landscape is becoming more patient-centric and outcome-focused. Companies investing in innovative therapies, long-acting injectables, supportive digital tools, and cost-effective biosimilars will be best positioned to lead the market over the next decade.

This report is also available in the following languages : Japanese (閉経後骨粗鬆症市場), Korean (폐경 후 골다공증 시장), Chinese (绝经后骨质疏松症市场), French (marché de l'ostéoporose postménopausique), German (Markt für postmenopausale Osteoporose), and Italian (Mercato dell'osteoporosi postmenopausale), etc.

Request for a sample of this research report at (Use Corporate Mail ID for Quick Response) @ https://exactitudeconsultancy.com/request-sample/72060

Our More Reports:

Vitamins, Calcium Hydrogen Phosphate and Calcium Gluconate Tablets Market
https://exactitudeconsultancy.com/reports/66396/vitamins-calcium-hydrogen-phosphate-and-calcium-gluconate-tablets-market

Osteoporosis Market
https://exactitudeconsultancy.com/reports/71004/osteoporosis-market

Hypoparathyroidism Market
https://exactitudeconsultancy.com/reports/71995/hypoparathyroidism-market

Postmenopausal Osteoporosis Market
https://exactitudeconsultancy.com/reports/72060/postmenopausal-osteoporosis-market

About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
https://bulletin.exactitudeconsultancy.com/

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https://exactitudeconsultancy.com/

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