Cancer Gene Therapy Market is expected to reach US$ 19.97 Billion by 2033 | Major Companies - Novartis AG, Pfizer, Adaptimmune Therapeutics.

Market Size and Growth:

The Global Cancer Gene Therapy Market Size reached US$ 3.36 Billion in 2023 with rise of US$ 3.97 Billion in 2024 is expected to reach US$ 19.97 Billion by 2033, growing at a CAGR of 19.8%during the forecast period 2025-2033. According to DataM Intelligence Report.

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The Cancer Gene Therapy Market involves the development, commercialization, and application of therapeutic strategies that modify or manipulate genes to treat cancer. It includes gene editing, gene silencing, and viral or non-viral vector-based therapies aimed at targeting cancer-causing genes, enhancing immune response, and improving patient outcomes, driving innovation in personalized oncology treatments globally.

United States: Recent Developments of Cancer Gene Therapy Market

✅ October 2025: FDA is expected to continue approving 10 to 20 cell and gene therapy products annually, showing strong regulatory support and confidence in cancer gene therapies, which drives market growth and innovation.

✅ November 2025: The U.S. oncology market is seeing a surge with increased investment in gene engineering, production capacity expansion, and ongoing clinical trials, particularly in CAR-T cell therapies that target aggressive and treatment-resistant cancers.

✅ December 2025: The cancer gene therapy market in the U.S. is projected to grow significantly due to high demand, ongoing clinical trial activity, advanced manufacturing capabilities, and strong venture capital investment supporting development and commercialization of breakthrough therapies.

Europe: Recent Developments of Cancer Gene Therapy Market

✅ October 2025: The European Innovation Council Cell and Gene Therapy Symposium conducted in October continues to foster collaboration, innovation, and networking across the region, accelerating development and commercialization of cancer gene therapies.

✅ November 2025: Germany is maintaining dominance in Europe's cancer gene therapy market, driven by strong R&D infrastructure, government spending, a robust biotech ecosystem, and the rollout of a national strategy for gene and cell therapies.

✅ December 2025: Europe's cell and gene therapy market growth is supported by EMA approvals, funding initiatives like Horizon Europe, increasing adoption of CAR-T therapies, and AI technologies enhancing therapy production efficiency, safety prediction, and biomarker identification.

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Major Mergers & Acquisitions & Strategic Moves in 2025:

✅ AstraZeneca acquired EsoBiotec (Belgium) - a biotech firm specializing in in‐vivo cell therapies - for up to $1 billion. The deal includes $425 million upfront plus up to $575 million in milestone payments. This was announced in March 2025 and completed by May 2025. The transaction bolsters AstraZeneca's push into "off-the-shelf" cell/gene therapies.

✅ Bristol Myers Squibb (BMS) acquired 2seventy bio (the company behind ABECMA - a CAR‐T therapy for multiple myeloma) for ≈ $286 million in cash. This gives BMS full ownership/control, likely simplifying commercialization and future developments of ABECMA.

✅ On the deal/partnership front, the landscape remains busy: several cell/gene‐therapy companies saw M&A or alliances in Q1 2025 (per a gene/cell therapy industry report).

Major Players:

Key companies in the Cancer Gene Therapy market include:

Novartis AG
Pfizer
Adaptimmune Therapeutics
Bluebird Bio, Inc.
Krystal Biotech, Inc.
Regulus Therapeutics
Biogenera

Segments Covered in the Cancer Gene Therapy Market:

By Therapy Type: Gene Induced Immunotherapy, Oncolytic Virotherapy, Gene Transfer Therapy.

By Indication: Brain Cancer, Lung Cancer, Breast Cancer, Pancreatic Cancer, Liver Cancer, Others.

By End-User: Hospitals, Cancer Research Institutes, Biotechnology & Pharmaceutical Companies.

Regional Analysis for Cancer Gene Therapy Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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Chapter Outline:

⏩ Market Overview: It contains five chapters, as well as information about the research scope, major manufacturers covered, market segments, Cancer Gene Therapy market segments, study objectives, and years considered.

⏩ Market Landscape: The competition in the Global Cancer Gene Therapy Market is evaluated here in terms of value, turnover, revenues, and market share by organization, as well as market rate, competitive landscape, and recent developments, transaction, growth, sale, and market shares of top companies.

⏩ Companies Profiles: The global Cancer Gene Therapy market's leading players are studied based on sales, main products, gross profit margin, revenue, price, and growth production.

⏩ Market Outlook by Region: The report goes through gross margin, sales, income, supply, market share, CAGR, and market size by region in this segment. North America, Europe, Asia Pacific, Middle East & Africa, and South America are among the regions and countries studied in depth in this study.

⏩ Market Segments: It contains the deep research study which interprets how different end-user/application/type segments contribute to the Cancer Gene Therapy Market.

⏩ Market Forecast: Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.

⏩ Research Findings: This section of the report showcases the findings and analysis of the report.

⏩ Conclusion: This portion of the report is the last section of the report where the conclusion of the research study is provided.

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Frequently asked questions:

➠ What is the global sales value, production value, consumption value, import and export of Cancer Gene Therapy market?

➠ Who are the global key manufacturers of the Cancer Gene Therapy Industry? How is their operating situation (capacity, production, sales, price, cost, gross, and revenue)?

➠ What are the Cancer Gene Therapy market opportunities and threats faced by the vendors in the global Cancer Gene Therapy Industry?

➠ Which application/end-user or product type may seek incremental growth prospects? What is the market share of each type and application?

➠ What focused approach and constraints are holding the Cancer Gene Therapy market?

➠ What are the different sales, marketing, and distribution channels in the global industry?

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