Cementless Total Knee Arthroplasty (TKA) Market to Reach USD 2.85 Billion by 2031: Mobile Bearing Implants Driving 58% of Global Demand | Exclusive Insights & Growth Forecast

Market Overview

The Cementless Total Knee Arthroplasty (TKA) Market was valued at USD 1.65 billion in 2024 and is projected to reach USD 2.85 billion by 2031, growing at a CAGR of 7.2% during the forecast period. The growth is primarily driven by the increasing prevalence of osteoarthritis, aging populations, and the global trend toward biological fixation techniques that improve implant longevity. Cementless implants provide better bone integration and reduce post-operative complications compared to cemented counterparts, making them a preferred choice among orthopedic surgeons.

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Cementless Total Knee Arthroplasty (TKA) refers to knee joint replacement procedures utilizing implants that achieve fixation through bone ingrowth instead of bone cement, ensuring long-term stability and enhanced patient mobility.

Key Developments:

United States
✅ October 2025: Zimmer Biomet unveiled its Persona OsseoTiTM Cementless Knee System, integrating 3D-printed titanium porous structures designed to enhance biological fixation and long-term implant stability.

✅ August 2025: Stryker Corporation expanded the rollout of its Mako Robotic-Assisted Cementless TKA platform across major orthopedic centers in the U.S., providing surgeons with enhanced precision and patient-specific alignment accuracy.

✅ May 2025: DePuy Synthes launched its ATTUNETM Cementless Knee System featuring proprietary PorocoatTM technology, improving early bone integration and reducing revision rates.

✅ February 2025: Smith & Nephew collaborated with the American Joint Replacement Registry (AJRR) to integrate digital outcome tracking for cementless TKA procedures, improving long-term data analytics and performance validation.

Global
✅ September 2025: Zimmer Biomet partnered with European orthopedic research institutions to study next-generation bioactive coatings for cementless implants, targeting enhanced osseointegration and reduced inflammatory response.

✅ June 2025: Smith & Nephew expanded its JOURNEYTM II Cementless Knee System into Asia-Pacific, strengthening its regional portfolio and addressing growing orthopedic demands in China, Japan, and South Korea.

✅ April 2025: B. Braun Melsungen AG introduced its ColloFitTM porous-coated knee implant line in Germany and France, emphasizing long-term fixation performance and minimally invasive surgical compatibility.

✅ January 2025: GROUP FH ORTHO launched its cementless femoral component series across Europe and the Middle East, improving implant longevity for active patients under 60 years of age.

Mergers & Acquisitions:

United States
✅ July 2025: Stryker Corporation acquired a California-based orthopedic robotics startup specializing in AI-assisted implant alignment systems to strengthen its cementless TKA precision technology portfolio.

✅ March 2025: Zimmer Biomet entered into a strategic acquisition of a materials engineering firm developing bioresorbable coatings to improve implant-bone interface healing rates.

✅ January 2025: DePuy Synthes formed a strategic partnership with a U.S.-based digital health analytics company to enhance patient monitoring and recovery optimization for post-TKA rehabilitation.

Global
✅ August 2025: Smith & Nephew completed the acquisition of GROUP FH ORTHO, expanding its cementless knee and hip arthroplasty portfolio and accelerating its European footprint.

✅ April 2025: B. Braun Melsungen AG partnered with an Indian orthopedic implant manufacturer to establish a joint venture for producing cost-effective cementless knee systems tailored for emerging markets.

✅ February 2025: Chongqing Xishan Science & Technology Co., Ltd. collaborated with Guangzhou Lety Medical Limited to co-develop lightweight cementless implant components using titanium-alloy additive manufacturing.

Competitive Landscape:
DePuy Synthes, GROUP FH ORTHO, Smith & Nephew, Stryker, Zimmer Biomet, B. Braun Melsungen AG, Zhengzhou YKinspection Enterprise Co., Ltd., Chongqing Xishan Science & Technology Co., Ltd., and Guangzhou Lety Medical Limited.

Market Segmentation:

By Product Type:
Mobile Bearing Implants 58% market share (USD 955 million, 2024): Favored for enhanced range of motion and wear resistance. Fixed Bearing Implants 42% market share (USD 695 million, 2024): Preferred in cost-sensitive markets and among elderly patients requiring stable fixation.

By End User:
Hospitals 68% market share (USD 1.12 billion): Benefit from advanced surgical infrastructure and higher procedural volumes. Specialty Clinics 24% (USD 396 million): Growing rapidly with rise in outpatient orthopedic surgeries.

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Regional Insights:

North America: 40% market share (USD 660 million, 2024):
North America remains the largest market for cementless TKA due to its advanced healthcare infrastructure, high surgeon expertise, and early adoption of robotic-assisted orthopedic procedures. The U.S. dominates within the region, accounting for over 85% of revenue, supported by favorable reimbursement frameworks, widespread insurance coverage, and strong hospital networks. Key growth drivers include integration of digital surgical planning, patient-specific instrumentation, and post-operative outcome tracking systems, which enhance surgical precision and reduce revision rates.

Europe: 30% (USD 495 million, 2024):
Europe shows robust demand, led by Germany, France, and the UK, where biologically integrated implants are widely accepted. Favorable reimbursement policies, government support for orthopedic innovation, and high public awareness of minimally invasive procedures underpin growth. Regional adoption is increasingly influenced by regulatory approvals for advanced implant materials, robotic surgery platforms, and digital rehabilitation programs, positioning Europe as a leader in clinical outcomes optimization.

Asia-Pacific: 20% (USD 330 million, 2024; CAGR 9.1%):
Asia-Pacific is the fastest-growing region, driven by rising geriatric population, increasing prevalence of osteoarthritis, and growing medical tourism in China, India, Japan, and South Korea. Investments in healthcare infrastructure, coupled with expansion of specialty orthopedic centers and awareness campaigns, are fueling adoption. Local manufacturers and partnerships with global players are introducing cost-effective cementless knee implants, enabling broader accessibility. Technological adoption, such as robotic-assisted surgeries and 3D-printed implant components, is accelerating market penetration.

Latin America, Middle East & Africa: 10% (USD 165 million, 2024):
Emerging markets in these regions are gradually expanding due to government healthcare modernization initiatives, private sector investments, and increasing awareness of advanced orthopedic procedures. Adoption is higher in urban healthcare centers, while rural regions remain underpenetrated. Opportunities exist in low-cost implant manufacturing, training programs for surgeons, and partnerships with global companies to improve accessibility.

Market Dynamics:

Drivers
Aging Population & Osteoarthritis Prevalence: Globally, osteoarthritis affects over 300 million people, with a rising elderly demographic driving demand for durable and minimally invasive knee replacement options. Technological Advancements: Innovations in porous titanium coatings, 3D-printed implant surfaces, and robotic navigation systems improve osseointegration, surgical accuracy, and long-term implant survival. Minimally Invasive Preferences: Surgeons increasingly prefer techniques that reduce incision size, post-operative pain, and recovery time, enhancing patient satisfaction and outcomes.

Restraints:
High Procedure Cost: Cementless TKA is more expensive than traditional cemented alternatives, which limits adoption in low-income countries and among self-pay patients. Complex Surgical Techniques: Successful outcomes require highly trained surgeons and advanced hospital infrastructure, restricting penetration in underdeveloped regions.

Opportunities:
3D-Printed Titanium Implants & AI Integration: Advanced manufacturing enables customized implant geometry, improving bone contact and functional outcomes. AI-assisted surgical systems optimize implant alignment, reduce revision risk, and streamline procedures. Emerging Market Expansion: Growing healthcare investments in China, India, and Southeast Asia create new opportunities for cost-effective cementless implant adoption. Digital Rehabilitation Solutions: Remote patient monitoring, mobile apps, and AI-based recovery analytics improve post-operative adherence, reduce complications, and accelerate functional recovery.

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