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Gene Therapy on Cardiovascular Disease Market Expands Rapidly as Technological Advancements Improve Safety Efficacy and Patient Outcomes

12-01-2025 08:40 AM CET | Health & Medicine

Press release from: Insightace Analytic Pvt Ltd.

Gene Therapy on Cardiovascular Disease Market

Gene Therapy on Cardiovascular Disease Market

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Gene Therapy on Cardiovascular Disease Market - (By Type (Viral Gene Therapy, Non-Viral Gene Therapy), By Application (Heart Disease, Vascular Disease)), Trends, Industry Competition Analysis, Revenue and Forecast To 2031."

According to the latest research by InsightAce Analytic, the Global Gene Therapy on Cardiovascular Disease Market is predicted to grow with a CAGR of 67.4% during the forecast period of 2024-2031.

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Gene therapy for cardiovascular diseases, particularly coronary artery disease, involves the delivery of genetic material into patient cells to prevent or treat pathological conditions. The primary aim of this therapeutic strategy is to enhance cardiac and vascular function by correcting genetic defects or modulating gene expression.

Viral vectors are the most commonly employed delivery systems for introducing therapeutic genes into cardiac and vascular tissues. Clinical research has shown encouraging results, including improvements in cardiac performance for patients with heart failure and inherited cardiovascular disorders. Ongoing research and development activities, supported by both public and private sector investment, are driving growth in the gene therapy market for coronary artery disease.

Concurrently, mRNA-based therapeutics are emerging as a novel treatment approach. These therapies work by delivering synthetic messenger RNA to target cells, enabling the production of specific therapeutic proteins by the patient's own cellular machinery. This methodology offers advantages such as improved safety profiles, lower manufacturing costs, and faster production timelines relative to traditional gene therapies.

However, a significant challenge facing the market is the scarcity of skilled professionals. The specialized expertise required for gene therapy research and clinical implementation remains in high demand, and the shortage of qualified personnel could impede sustainable growth and operational efficiency in this rapidly evolving sector.

List of Prominent Players in the Gene Therapy on Cardiovascular Disease Market:
• Biogen
• Novartis
• Gilead Sciences
• Sarepta Therapeutics
• Alnylam Pharmaceuticals
• Amgen
• Spark Therapeutics
• Akcea Therapeutics
• Sunway Biotech
• bluebird bio
• SIBIONO
• AnGes
• Orchard Therapeutics
• Other Market Players

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Market Dynamics
Drivers:
The expansion of the gene therapy market for cardiovascular diseases is primarily driven by the rising prevalence of chronic conditions, including cancer and rare genetic disorders. Gene therapy's increasing recognition as an effective and innovative treatment modality-initially established in oncology-is facilitating its broader application in cardiovascular care. This growth trajectory is further reinforced by government funding initiatives and favorable policy frameworks that encourage the development and adoption of gene therapy solutions within the cardiovascular disease sector.

Challenges:
Despite its promising prospects, the market encounters notable constraints. High capital expenditure requirements, a limited availability of skilled professionals, and the absence of standardized clinical protocols-particularly in emerging regions-pose significant barriers. These challenges are compounded by delays in regulatory approvals, often influenced by pandemic-related disruptions to supply chains.

Additionally, the elevated costs associated with the development and administration of gene therapies are frequently passed on to patients, restricting access for those without comprehensive insurance coverage. The absence of well-established reimbursement frameworks and limited insurer participation, especially for treatments addressing rare conditions, further restrict market penetration. Concerns over long-term safety and efficacy also contribute to cautious adoption among payers, collectively moderating the pace of market growth.

Regional Trends:
North America is projected to maintain a dominant position in the cardiovascular gene therapy market, supported by a high incidence of cardiovascular disorders, substantial research and development investment, rapid technological advancements, and favorable regulatory policies. Increased healthcare expenditure further reinforces growth in the region. Europe is also demonstrating strong market expansion, underpinned by a large patient population, heightened public awareness, increased research initiatives, and a relatively high prevalence of cancer and infectious diseases. Together, these factors position North America and Europe as critical contributors to the global growth of gene therapy within cardiovascular healthcare.

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Recent Developments:
• In Nov 2023, Amgen presented new information at the American Heart Association (AHA) Scientific Sessions 2023 in Philadelphia, which further supports the safety and effectiveness of Repatha® (evolocumab) based on the FOURIER Open Label Extension (OLE) [FOURIER-OLE] trial. The presentations will specifically address the reduction of LDL "bad" cholesterol (LDL-C), which is a well-known risk factor for cardiovascular disease (CVD).
• In Aug 2023, Lexeo Therapeutics received a strategic investment from Sarepta Therapeutics to aid in the advancement of Lexeo's cardiovascular gene therapies. The companies will investigate the creation of innovative gene therapy candidates for various cardiovascular diseases as part of this investment.

Segmentation of Gene Therapy on Cardiovascular Disease Market-
By Type-
• Viral Gene Therapy
• Non-Viral Gene Therapy
By Application-
• Heart Disease
• Vascular Disease
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa

Read Overview Report- https://www.insightaceanalytic.com/report/gene-therapy-on-cardiovascular-disease-market/2451

About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.

Contact us:
InsightAce Analytic Pvt. Ltd.
Visit: https://www.insightaceanalytic.com/
Tel : +1 607 400-7072
Asia: +91 79 72967118
info@insightaceanalytic.com

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