Press release
Chronic Hepatitis B (CHB) Epidemiology Market to Reach USD 6.9 Billion by 2034
The Global Chronic Hepatitis B (CHB) Epidemiology Market is expanding as health systems strengthen screening, prevention, and clinical management strategies for Hepatitis B-a major global driver of cirrhosis, liver failure, and hepatocellular carcinoma (HCC). According to Exactitude Consultancy, the market is projected to grow from USD 3.8 billion in 2023 to USD 6.9 billion by 2034, recording a CAGR of 6.1%.The market includes diagnostics, antiviral drugs, epidemiological surveillance systems, disease modeling tools, and public health vaccination initiatives aimed at monitoring and reducing HBV prevalence.
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Key Takeaways
• Market Size 2023: USD 3.8 billion
• Market Size 2034: USD 6.9 billion
• CAGR (2024-2034): 6.1%
• Largest Segment: Diagnostic testing & antiviral therapy
• Fastest-Growing Area: Digital epidemiology, AI-based disease forecasting, and HBV elimination programs
Market Story
Chronic Hepatitis B affects more than 250 million people worldwide and remains a significant public health challenge, particularly in Asia-Pacific and sub-Saharan Africa. While vaccination has drastically reduced new infections, millions still require long-term monitoring and antiviral treatment.
Key growth drivers include:
• Expansion of HBV screening programs
• Universal newborn vaccination policies
• Rising incidence of chronic HBV complications (HCC, cirrhosis)
• Adoption of molecular diagnostic tests (PCR, viral load testing)
• New antiviral combinations and immunotherapy research
• Global push toward HBV elimination by 2030 under WHO guidelines
Digital health, AI-driven surveillance, and national HBV registries are emerging as major tools for better disease tracking and forecasting.
Market Segments
By Diagnostic Type
• HBsAg Screening Tests (Largest Segment)
• HBV DNA Quantification & Viral Load Tests
• HBeAg & Anti-HBe Marker Analysis
• Liver Function Tests
• HBV Genotyping Assays
• Fibrosis & Liver Damage Assessment Tools
- FibroScan
- FibroTest
- Ultrasound, CT, MRI
PCR-based viral load testing shows the strongest global adoption.
By Treatment/Management Type
• Nucleos(t)ide Analogues (First-Line Therapy)
- Tenofovir (TDF/TAF)
- Entecavir
• Interferon-Based Therapies
• Combination Therapy (Emerging)
• Pipeline Immunotherapies & Functional Cure Candidates
- siRNA-based drugs
- Core protein modulators
- Checkpoint inhibitors
- Therapeutic vaccines
• Liver Complication Management
- HCC monitoring
- Cirrhosis management
- Liver transplant pathways
Tenofovir and entecavir remain the backbone of global CHB treatment.
By Surveillance & Epidemiology Type
• National & Regional HBV Epidemiology Databases
• Disease Burden Modeling Tools
• AI-Powered Infection Forecasting Software (Fastest Growing)
• Digital Registries & Public Health Intelligence Platforms
• Outbreak Reporting Systems
Governments increasingly rely on predictive epidemiology to meet HBV elimination targets.
By End User
• Hospitals & Liver Care Centers (Largest End User)
• Diagnostic Laboratories
• Public Health Departments
• Research Institutes
• Pharmaceutical Companies
• Digital Epidemiology Platforms
Hospitals and specialty liver clinics oversee long-term patient management and antiviral therapy.
Explore Full Report here: https://exactitudeconsultancy.com/reports/73640/chronic-hepatitis-b-chb-epidemiology-analysis-and-forecast-to-2034-market
Recent Industry Developments
• 2024 - Gilead Sciences advanced trials for siRNA-based functional cure candidates.
• 2023 - Johnson & Johnson progressed therapeutic vaccine programs targeting HBV surface antigens.
• 2023 - Roche Diagnostics launched improved quantitative PCR kits for viral load monitoring.
• 2023 - WHO updated HBV elimination guidelines for high-burden countries.
• 2023 - Abbott expanded rapid HBsAg screening tools for low-resource settings.
Expert Quote
"Strengthening global HBV screening, implementing high-quality diagnostics, and accelerating functional cure research are essential steps in reducing the long-term burden of Chronic Hepatitis B."
- Irfan Tamboli, Business Development Executive, Exactitude Consultancy
Key Market Drivers
1. Rising Global HBV Prevalence
CHB remains a major contributor to liver cancer and failure.
2. WHO-Led HBV Elimination Goals
Countries scaling vaccination, testing, and treatment programs drive significant market demand.
3. Increase in High-Accuracy Diagnostic Adoption
PCR and genotyping support precise clinical decision-making.
4. Advancements in Antiviral and Immunotherapy R&D
Functional HBV cure is becoming a realistic long-term possibility.
5. Growth in Digital Epidemiology
AI-based surveillance platforms enable real-time spread forecasting.
Forecast Outlook (2024-2034)
Key trends shaping the market include:
• Widespread rollout of digital HBV registries
• Functional cure candidates expected to reach late clinical stages
• AI-powered risk stratification for HCC and cirrhosis
• Biomarker-driven personalized therapy selection
• Improved access to treatment in low-income regions
By 2034, CHB management will be significantly more predictive, personalized, and preventive.
Regional Insights
Asia-Pacific (Largest Disease Burden & Market Share)
China, India, Vietnam, Philippines, South Korea - regions with long-term HBV prevalence.
Middle East & Africa
High incidence and limited screening infrastructure driving public health investments.
North America
Growing demand for advanced diagnostics and antiviral therapies.
Europe
Strong screening policies, improved surveillance systems, and active clinical research.
Conclusion
The Chronic Hepatitis B Epidemiology Market is evolving rapidly as global health systems strengthen screening, diagnostics, antiviral therapy, and disease surveillance. With rising investment in functional cure research and digital health tools, CHB management will undergo significant transformation through 2034.
This report is also available in the following languages : Japanese (慢性B型肝炎(CHB)疫学分析と2034年市場予測), Korean (만성 B형 간염(CHB) 역학 분석 및 2034년 시장 전망), Chinese (慢性乙型肝炎(CHB)流行病学分析及至2034年市场预测), French (Analyse épidémiologique et prévisions du marché de l'hépatite B chronique (HBC) jusqu'en 2034), German (Epidemiologische Analyse und Prognose des Marktes für chronische Hepatitis B (CHB) bis 2034), and Italian (Analisi epidemiologica dell'epatite B cronica (CHB) e previsioni di mercato fino al 2034), etc.
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About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
https://bulletin.exactitudeconsultancy.com/
https://www.thehealthanalytics.com/
https://www.analytica.global/
https://www.marketintelligencedata.com/
https://www.marketinsightsreports.com/
https://exactitudeconsultancy.com/
Connect Us:
Irfan Tamboli
PHONE NUMBER +1 (704) 266-3234
EMAIL ADDRESS: sales@exactitudeconsultancy.com
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