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NGS-Based RNA Sequencing Market to Reach USD 16.8 Billion by 2030

11-28-2025 11:08 AM CET | Health & Medicine

Press release from: Exactitude Consultancy

NGS-Based RNA Sequencing

NGS-Based RNA Sequencing

The Global NGS-Based RNA Sequencing Market is expanding rapidly as next-generation sequencing (NGS) technologies transform transcriptomics, cancer diagnostics, drug development, and personalized medicine. According to Exactitude Consultancy, the market will grow from USD 6.2 billion in 2023 to USD 16.8 billion by 2030, registering a strong CAGR of 15.2%.
RNA sequencing (RNA-Seq) provides a complete, unbiased view of the transcriptome-enabling detection of gene expression patterns, alternative splicing, gene fusions, single-cell variation, and disease-specific biomarkers.

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Key Takeaways
• Market Size 2023: USD 6.2 billion
• Market Size 2030: USD 16.8 billion
• CAGR (2024-2030): 15.2%
• Core Drivers: Precision oncology, single-cell sequencing, biomarker discovery, drug development, and falling NGS costs.
• Fastest Growing Segment: Single-cell RNA-Seq & long-read RNA sequencing.
• Key End Users: Pharma, biotech, academic institutes, CROs, and clinical labs.

Market Story
RNA sequencing has become one of the most powerful genomic tools in biomedical research. Its ability to decode the entire transcriptome with high sensitivity and precision has made it essential for:
• Cancer classification and mutation discovery
• Drug target identification
• Immune profiling for immunotherapy
• Rare disease diagnosis
• Vaccine development
• Single-cell transcriptomics
• Gene expression analysis
Advances such as single-cell RNA-Seq (scRNA-Seq), spatial transcriptomics, long-read sequencing, and real-time sequencing are accelerating adoption in both research and clinical applications.
With oncology, neurodegenerative diseases, infectious diseases, and personalized medicine programs expanding globally, NGS-based RNA sequencing is now a central pillar of modern molecular biology.

Market Segments
By Product & Service
• NGS Instruments
• RNA-Seq Kits & Consumables (Largest Segment)
• Library Preparation Kits
• Sequencing Reagents
• Bioinformatics Software & Services
• Data Analysis Platforms
• Clinical RNA-Seq Services
Kits and consumables dominate due to high repeat-purchase demand.

By Technology
• Whole Transcriptome Sequencing (WTS)
• Single-Cell RNA Sequencing (scRNA-Seq)
• Targeted RNA Sequencing
• Long-Read RNA Sequencing (Fastest Growing)
• De Novo RNA Sequencing
• Spatial Transcriptomics
Single-cell and long-read RNA-Seq are reshaping disease research.

By Application
• Oncology (Largest Application)
• Drug Discovery & Development
• Genetic Disease Research
• Immunology & Vaccine Research
• Biomarker Discovery
• Agrigenomics & Plant Transcriptomics
• Neuroscience Research
Oncology drives more than 40% of RNA-Seq demand globally.

By End User
• Pharmaceutical & Biotechnology Companies
• Academic & Research Institutions
• Contract Research Organizations (CROs)
• Clinical & Diagnostic Laboratories
• Government & Public Health Centers
Biotech and research institutes represent the largest client base.

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Recent Industry Developments
• 2024 - Illumina expanded its RNA-Seq portfolio with new long-read sequencing workflows.
• 2024 - PacBio advanced HiFi long-read RNA sequencing for improved isoform detection.
• 2023 - Oxford Nanopore Technologies launched real-time full-length RNA sequencing platforms.
• 2023 - Thermo Fisher Scientific introduced upgraded RNA-Seq library preparation kits for oncology.
• 2023 - 10x Genomics strengthened its single-cell and spatial transcriptomics solutions.

Expert Quote
"RNA sequencing has moved from research labs into core clinical pipelines. Its ability to decode gene expression and uncover disease signatures makes it one of the most transformative tools in modern precision medicine."
- Irfan Tamboli, Business Development Executive, Exactitude Consultancy

Key Market Drivers
1. Surging Demand for Precision Oncology
RNA-Seq enables detection of fusion genes, tumor evolution, immune signatures, and therapy response markers.
2. Growth of Single-Cell & Spatial Transcriptomics
Single-cell RNA-Seq provides unmatched insight into cellular heterogeneity and disease pathways.
3. Technological Advancements in Long-Read Sequencing
Platforms like PacBio and ONT improve isoform detection, transcript structure, and splicing analysis.
4. Declining NGS Costs
Affordable sequencing increases accessibility across academia, diagnostics, and pharma.
5. Expansion of Drug Discovery Pipelines
RNA-Seq accelerates target validation, toxicity studies, and pathway analysis.

Forecast Outlook (2024-2030)
The future of RNA-Seq will be shaped by:
• AI-driven transcriptomics analysis
• Adoption of clinical RNA-Seq for cancer diagnosis
• Integration of RNA-Seq with proteomics & multi-omics
• Growth in direct RNA sequencing
• Real-time nanopore sequencing for infectious disease outbreaks
By 2030, single-cell, long-read, and clinical-grade RNA-Seq will dominate the transcriptomics ecosystem.

Regional Insights
North America
Largest market driven by strong genomics research, biotech ecosystem, and funding.
Europe
Significant adoption in cancer genomics, multi-omics, and academic research.
Asia-Pacific
Fastest-growing region (CAGR > 16%) with investments in precision medicine across China, India, Japan, and South Korea.
Latin America & Middle East
Increasing genomics programs and national genome initiatives support growth.

Conclusion
The NGS-Based RNA Sequencing Market is set for high growth as RNA-Seq becomes essential for cancer research, drug discovery, biomarker identification, and personalized medicine. Advanced sequencing platforms, AI-powered analytics, and multi-omics integration will define the next decade of transcriptomics innovation.

This report is also available in the following languages : Japanese (NGSベースのRNAシーケンシング市場), Korean (NGS 기반 RNA 시퀀싱 시장), Chinese (基于NGS的RNA测序市场), French (Marché du séquençage d'ARN basé sur le NGS), German (Markt für NGS-basierte RNA-Sequenzierung), and Italian (Mercato del sequenziamento dell'RNA basato su NGS), etc.

Request for a sample of this research report at (Use Corporate Mail ID for Quick Response) @ https://exactitudeconsultancy.com/request-sample/73496

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About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
https://bulletin.exactitudeconsultancy.com/

https://www.thehealthanalytics.com/

https://www.analytica.global/

https://www.marketintelligencedata.com/

https://www.marketinsightsreports.com/

https://exactitudeconsultancy.com/

Connect Us:
Irfan Tamboli
PHONE NUMBER +1 (704) 266-3234
EMAIL ADDRESS: sales@exactitudeconsultancy.com

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