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Future of the Global Low-Grade Glioma Market: Trends, Innovations, and Key Forecasts Through 2034

11-20-2025 07:48 AM CET | Health & Medicine

Press release from: The Business Research Company

Low-Grade Glioma

Low-Grade Glioma

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Low-Grade Glioma Market Size Growth Forecast: What to Expect by 2025?
The valuation of the low-grade glioma sector has witnessed considerable escalation recently, projected to transition from its 2024 figure of 1.39 billion USD to 1.47 billion USD by 2025, reflecting a consistent annual expansion rate of 5.8 percent; this upward trajectory throughout the past period is traceable to heightened consciousness surrounding cerebral tumors, amplified financial support propelling oncological investigation, a rise in specialized designations for rare disease medications, the broadening reach of virtual healthcare solutions, and improved pathways to medical services.

How Will the Low-Grade Glioma Market Size Evolve and Grow by 2029?
Anticipation surrounds the market for low-grade glioma, projecting robust expansion across the coming years; this sector is forecast to reach a valuation of $1.84 billion by 2029, achieving a compound annual growth rate (CAGR) of 5.7%, a surge fueled by demographics such as an expanding elderly populace, escalating healthcare spending, a greater detection rate of brain tumors, bolstered governmental support programs, and the increasing occurrence and documented cases of more aggressive high-grade gliomas, while key developments expected to shape this period involve progress in diagnostic imaging modalities, innovative strides in radiation-based treatments, the rollout of novel chemotherapy protocols, an uptick in ongoing clinical investigations, and the broader incorporation of immunotherapeutic approaches.

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What Drivers Are Propelling the Growth of Low-Grade Glioma Market Forward?
Anticipated increases in brain tumor occurrences are projected to boost the market for low-grade glioma in the near future, given that a brain tumor signifies an aberrant proliferation of cells within or near the brain, which can manifest as non-cancerous or cancerous; this upward trend in brain tumor rates is attributed to elements like greater radiation exposure, environmental contaminants, inherited susceptibilities, and the aging process, and low-grade glioma proves beneficial in addressing brain tumors through the application of sophisticated diagnostic methods and specific treatment modalities such as surgical intervention, radiotherapy, and chemotherapy, all aimed at retarding tumor advancement, maintaining adequate neurological capabilities, and enhancing patient results, thus emphasizing the critical nature of prompt identification and individualized care for managing other brain tumors exhibiting comparable growth characteristics, exemplified by data released in October 2023 from The Central Brain Tumor Registry of the United States (CBTRUS), a US non-profit that reported the global incidence of primary malignant brain tumors in 2022 was roughly 3.5 cases per 100,000 people, noting that high-income nations experienced elevated rates (4.9 per 100,000) compared to low-middle-income (2.4 per 100,000) and low-income nations, consequently making the increasing prevalence of brain tumors a key stimulant for the expansion of the low-grade glioma market.

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Which Emerging Trends Are Transforming the Low-Grade Glioma Market in 2025?
Leading enterprises within the low-grade glioma sector are strategically prioritizing the deployment of combined treatment modalities alongside precision medicine approaches, particularly those leveraging drugs targeting genetic modifications, as a means to secure superior market positioning and improve therapeutic outcomes for pediatric cases afflicted by low-grade glioma. These genetic alteration pharmaceuticals represent a class of precision treatments engineered to counteract or modulate distinct genetic anomalies or aberrations within cells, thereby aiding in the management of malignancies like cancer by disrupting the cellular mechanisms that fuel aberrant proliferation. Illustratively, in May of 2024, the American biotechnology firm Day One Biopharmaceuticals successfully introduced Tovorafenib (marketed as Ojemda), following its expedited authorization from the FDA. This specific targeted treatment is intended for pediatric patients aged six months upwards diagnosed with recurrent or inoperable low-grade glioma that harbors BRAF gene alterations, providing the significant advantage of a simple, once-weekly oral dosing regimen that tackles a critical gap in care for children with pediatric LGG who previously faced restricted treatment pathways.

What Are the Key Segments in the Low-Grade Glioma Market?
The low-grade gliomamarket covered in this report is segmented -

1) By Drug Type: Trametinib; Dabrafenib; Ivosidenib; Mirdametinib
2) By Treatment: Surgery; Chemotherapy; Radiation
3) By Route Of Administration: Topical; Oral
4) By Distribution Channel: Online Pharmacies; Hospital Pharmacies; Retail Pharmacies

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Who Are the Key Players Shaping the Low-Grade Glioma Market's Competitive Landscape?
Major companies operating in the low-grade glioma market are McKesson Corporation, F. Hoffmann-La Roche Ltd, Merck & Co. Inc., Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, Daiichi Sankyo Company Limited, Ipsen S.A., BeiGene Ltd., NovoCure Limited, Les Laboratoires Servier, Day One Biopharmaceuticals Inc., CStone Pharmaceuticals Co. Ltd., AnHeart Therapeutics Inc., Apollomics Inc., Agios Pharmaceuticals Inc., BioMed Valley Discoveries Inc., Avistone Biotechnology Co. Ltd., NextSource Biotechnology LLC, Sunesis Pharmaceuticals Inc.

What Geographic Markets Are Powering Growth in the Low-Grade Glioma Market?
North America was the largest region in the low-grade glioma market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the low-grade glioma market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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