Press release
Diabetic Neuropathic Pain Pipeline Accelerates With 10+ Novel Therapies in Development, Reports DelveInsight
Diabetic Neuropathic Pain Pipeline
DelveInsight's latest analysis reveals that more than 10 pharmaceutical and biotech companies worldwide are actively advancing over a dozen promising therapeutic candidates for Diabetic Neuropathic Pain. The comprehensive review evaluates ongoing clinical trials, mechanisms of action, routes of administration, and key developmental milestones shaping the future treatment landscape.
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Key Highlights from DelveInsight's Diabetic Neuropathic Pain Pipeline Report
• Numerous global players continue to invest in innovative treatment approaches for Diabetic Neuropathic Pain, reflecting steady scientific and clinical advancement.
• Leading Diabetic Neuropathic Pain companies in the development pipeline include Rigshospitalet, CSPC Ouyi Pharmaceutical, Reata, Lexicon Pharmaceuticals, Jemincare, Eli Lilly and Company, GlaxoSmithKline, Apurano Pharmaceuticals, and several others.
• Key investigational therapies currently in various clinical phases include Incobotulinumtoxin-A (100 UNIT Injection), pregabalin sustained-release formulations, RTA 901, LX9211, JMKX000623, LY3556050, GSK3858279, Adezunap (AP707), and more-each anticipated to influence the treatment landscape over the coming years.
Recent Pipeline Developments in Diabetic Neuropathic Pain Pipeline
• March 2025: Lexicon Pharmaceuticals announced positive topline results from the Phase 2b PROGRESS study of LX9211 (pilavapadin), the company's oral AAK1 inhibitor being studied in patients with moderate to severe diabetic peripheral neuropathic pain (DPNP).
• November 2024: Enrollment for Lexicon's Phase IIb PROGRESS trial surpassed expectations, with 494 participants recruited-about 20% above the initial target. Topline data is expected early next year.
• May 2024: Medidata (Dassault Systèmes) partnered with Lexicon Pharmaceuticals to support the advancement of LX9211 trials. LX9211 may become the first new non-opioid neuropathic pain therapy to gain approval in over two decades.
• January 2024: Neuralace Medical received FDA clearance for Axon Therapy (mPNS), marking the first non-invasive magnetic peripheral nerve stimulation device approved for chronic Painful Diabetic Neuropathy (PDN).
Diabetic Neuropathic Pain Overview
Diabetic Neuropathic Pain (DNP) arises from nerve damage caused by persistent hyperglycemia in people with diabetes. It often affects the limbs and causes sensations such as burning, numbness, tingling, or sharp pain. Risk factors include long-standing diabetes, obesity, and poor glycemic control. Treatment strategies typically combine glucose management, pharmacotherapy (including anticonvulsants and antidepressants), and lifestyle modifications.
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Diabetic Neuropathic Pain Pipeline Therapies in Development
Key candidates undergoing clinical evaluation include:
• Incobotulinumtoxin-A 100 UNIT Injection - Rigshospitalet
• Pregabalin SR tablets - CSPC Ouyi Pharmaceutical
• RTA 901 - Reata
• LX9211 - Lexicon Pharmaceuticals
• JMKX000623 - Jemincare
• LY3556050 - Eli Lilly
• GSK3858279 - GlaxoSmithKline
• Adezunap (AP707) - Apurano Pharmaceuticals
Diabetic Neuropathic Pain Drug Classification by Route of Administration (ROA)
Pipeline candidates fall under multiple ROAs, including:
• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical
Diabetic Neuropathic Pain Drug Molecule Types in Development
Therapies are being explored across several molecular categories:
• Small molecules
• Monoclonal antibodies
• Recombinant fusion proteins
• Peptides
• Polymers
• Gene therapies
Comprehensive Diabetic Neuropathic Pain Pipeline Assessment Includes:
• Product type categorization
• Stage-wise progression (Phase I-III, preclinical, discovery)
• ROA-based evaluation
• Molecular classification
• Active vs. discontinued program tracking
DelveInsight's report covers 12+ therapies at various clinical stages, from advanced trials to early discovery.
Download the full pipeline report: https://www.delveinsight.com/sample-request/diabetic-neuropathic-pain-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Leading Companies in the Diabetic Neuropathic Pain Therapeutics Market
Prominent Diabetic Neuropathic Pain Companies include Eli Lilly, Regenacy Pharmaceuticals, Helixmith, Vertex Pharmaceuticals, Eisai, NeuroBo Pharmaceuticals, AstraZeneca, Centrexion Therapeutics, Aptinyx, Pure Green Pharmaceuticals, Dong-A ST, Daiichi Sankyo, NeurogesX, Lexicon Pharmaceuticals, and others.
Diabetic Neuropathic Pain Market Outlook
• Drivers Boosting Market Growth
• Increasing diabetes prevalence
• Rising unmet need for effective pain management
• Ageing population
• Advancements in drug development technologies
• Supportive regulatory incentives
Challenges Hindering Market Expansion
• Complex pathophysiology and variability among patients
• Absence of reliable predictive biomarkers
• Safety concerns in long-term treatments
• Clinical trial design limitations
• Reimbursement and healthcare access barriers
Download Sample PDF Report to know more about Diabetic Neuropathic Pain drugs and therapies
https://www.delveinsight.com/sample-request/diabetic-neuropathic-pain-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Scope of the Diabetic Neuropathic Pain Clinical Trials Report
• Global: Coverage
• Key Companies: Rigshospitalet, CSPC Ouyi Pharmaceutical, Reata, Lexicon Pharmaceuticals, Jemincare, Eli Lilly, GSK, Apurano Pharmaceuticals, and more
• Key Therapies: Incobotulinumtoxin-A, pregabalin SR tablets, RTA 901, LX9211, JMKX000623, LY3556050, GSK3858279, Adezunap (AP707), etc.
• In-depth analysis of market dynamics, emerging therapies, and development challenges
Contact Us:
Ankit Nigam
Manager Marketing
info@delveinsight.com
+14699457679
About DelveInsight
DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.
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