United States RNA Sequencing Market to Grow at 12.20% CAGR Through 2031- Exclusive Report by DatamIntelligence

Leander, Texas, United States - Nov. 19. 2025 "The RNA Sequencing Market is projected to grow at a CAGR of 14.20% during the forecast period 2024-2031."

RNA Sequencing (RNA-Seq), a next-generation sequencing technology, enables comprehensive analysis of transcriptomes to study gene expression, alternative splicing, and non-coding RNAs. While current RNA-Seq platforms provide high throughput and accurate quantification of transcripts, challenges remain in data analysis complexity, high costs, and limited standardization across laboratories, which can impact reproducibility and large-scale clinical applications.

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☛ United States: Recent Industry Developments

✅ November 2025: Illumina and Thermo Fisher Scientific expanded their RNA sequencing platforms in U.S. research centers to support high throughput genomics and personalized medicine initiatives. The upgrades feature faster sequencing speeds and enhanced accuracy, enabling advanced transcriptomic studies for cancer and rare diseases.

✅ October 2025: PacBio launched a next generation long read RNA sequencing system optimized for full length transcript analysis. The system allows U.S. academic and clinical researchers to explore alternative splicing events and gene isoforms with higher resolution. Early adoption improved biomarker discovery workflows.

✅ September 2025: BGI Americas partnered with major hospitals and biotech firms to implement cloud based RNA sequencing pipelines. The collaboration supports rapid data analysis and integration with AI tools for diagnostics and drug development. Demand surged due to increased focus on precision medicine and immunotherapy research.

☛ Japan: Recent Industry Developments
✅ November 2025: Takara Bio launched advanced RNA sequencing kits and reagents in Japan designed for single cell and spatial transcriptomics applications. The products aim to accelerate genomics research in oncology and regenerative medicine.

✅ October 2025: RIKEN and local biotech companies deployed high throughput RNA sequencing platforms in research hospitals. The initiative supports large scale studies on genetic diseases and contributes to Japan's national precision medicine program.

✅ September 2025: Illumina Japan expanded its service offerings for RNA sequencing, including cloud based bioinformatics and automated library preparation. The move improves turnaround time for research institutes and clinical laboratories, enhancing the country's genomics research infrastructure.

☛ Core Catalysts Behind Market Growth:

Increasing adoption of RNA sequencing technologies in genomics research, personalized medicine, and biomarker discovery is driving market growth globally.

Rising prevalence of genetic disorders, cancer, and infectious diseases is fueling the need for transcriptomic analysis and advanced diagnostic applications.

Technological advancements in next generation sequencing (NGS), high throughput platforms, and bioinformatics tools are enhancing data accuracy, speed, and scalability.

Growing investments by research institutions, pharmaceutical companies, and government initiatives in genomics and precision medicine are further accelerating market expansion.

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☛ Market Segmentation:

By Products & Services:
The market is segmented into Sample Preparation Products, Data Analysis, Storage & Management, and RNA Sequencing Services. Sample Preparation Products dominate with the largest share of around 40% due to their critical role in ensuring high-quality RNA extraction and library preparation. Data Analysis and Storage hold roughly 25-30% share, driven by increasing volumes of sequencing data and demand for advanced bioinformatics solutions. RNA Sequencing Services account for approximately 20-25%, expanding as research institutions and biotech companies outsource sequencing for efficiency and cost-effectiveness.

By Technology:
Technology segments include Ion Semiconductor Sequencing, Single Molecule Real Time Sequencing, Nanopore Sequencing, and Sequencing by Synthesis. Sequencing by Synthesis leads the market with a share of about 45% due to its high accuracy, scalability, and widespread adoption in research and clinical applications. Nanopore Sequencing is a fast growing segment with around 15-20% share, valued for portability, long-read capability, and real-time data generation. Ion Semiconductor Sequencing and Single Molecule Real Time Sequencing together hold roughly 25-30% share for specialized genomic applications.

By Application:
Applications cover Small RNA Sequencing, Expression Profiling Analysis, De Novo Transcriptome Assembly, Variant Calling, and Transcriptome Epigenetics. Expression Profiling Analysis dominates with about 40% share, driven by extensive use in disease research, biomarker discovery, and gene expression studies. De Novo Transcriptome Assembly and Variant Calling hold around 25-30% share, expanding as genomics research focuses on novel gene identification and genetic variation analysis. Small RNA Sequencing and Transcriptome Epigenetics together account for approximately 15-20% share, reflecting emerging functional genomics applications.

By End-User:
End-users include Research Centers, Biotechnology Labs, Healthcare Centers, and Others. Research Centers hold the largest share of around 45%, fueled by intensive genomic research, drug discovery, and functional genomics studies. Biotechnology Labs account for approximately 25-30%, while Healthcare Centers represent about 15-20%, growing with personalized medicine, clinical diagnostics, and translational research. Others make up roughly 5-10%, including academic institutions and contract research organizations.

☛ Key Players:
GE Healthcare, Siemens Healthineers, Fujifilm (FUJIFILM Toyama Chemical Co. Ltd), Bracco, Canon Medical Systems Corporation, Nihon Medi-Physics Co. (Sumitomo Chemical Co. Ltd), ATOX Co., Ltd., IBA Radiopharma Solutions

Highlights:

GE Healthcare - Holds a leading position in advanced SPECT and PET device installations, accounting for an estimated 28% of Japan's nuclear imaging market, with its integrated PET-CT systems widely deployed across major hospitals and diagnostic centers.

Fujifilm (FUJIFILM Toyama Chemical Co. Ltd) - Along with Siemens Healthineers, captures approximately 24% market share, focusing on cutting edge radiopharmaceutical development and imaging technology upgrades for oncology and cardiology diagnostics.

Siemens Healthineers - Provides advanced molecular imaging systems and radiopharmaceutical solutions, contributing significantly to early disease detection and precision diagnostics in Japan.

Canon Medical Systems Corporation - Reported a 13% year-over-year growth in PET imaging solutions in 2024, driven by increasing provider investment in early cancer detection programs.

Nihon Medi-Physics Co. (Sumitomo Chemical Co. Ltd) - A key domestic supplier of radiopharmaceuticals, ensuring steady supply and innovation in nuclear medicine diagnostics.

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☛ Regional Analysis:

North America (40-45% share):
Leads the global RNA sequencing market due to advanced genomics research infrastructure, high adoption of next generation sequencing (NGS) technologies, and strong investments in precision medicine and biotechnology. The U.S. dominates the regional market with extensive funding for research institutions, pharmaceutical companies, and academic collaborations.

Europe (25-30% share):
Shows steady growth driven by well established molecular biology research, genomics focused healthcare initiatives, and the presence of key market players in countries such as Germany, the U.K., and France. Strong funding for academic and industrial research in RNA technologies supports adoption.

Asia-Pacific (20-25% share):
Fastest growing region fueled by rising biotechnology investments, growing genomics research, and increasing focus on personalized medicine in China, Japan, India, and South Korea. Expanding collaborations between academic institutions and biotech companies accelerate market penetration.

Latin America (3-5% share):
Experiences gradual growth supported by emerging biotechnology research, increasing government genomics initiatives, and adoption of RNA-based diagnostics in Brazil, Mexico, and Argentina.

Middle East (2-3% share):
Emerging market driven by government funded genomics projects, adoption of advanced diagnostic technologies, and increasing research in personalized medicine, particularly in UAE, Saudi Arabia, and Qatar.

Africa (1-2% share):
Gradually growing with opportunities in academic research, infectious disease studies, and increasing investments in genomics infrastructure in South Africa, Egypt, and select other countries. Limited awareness and infrastructure remain key constraints.

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