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Soaring Demand Set to Propel Mammalian Cell Fermentation Technology Market to $87.07 Billion by 2029

11-19-2025 08:10 AM CET | Health & Medicine

Press release from: The Business Research Company

Mammalian Cell Fermentation Technology

Mammalian Cell Fermentation Technology

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What Is the Expected CAGR for the Mammalian Cell Fermentation Technology Market Through 2025?
The market encompassing mammalian cell fermentation technology has witnessed swift expansion lately, projected to move from its 2024 valuation of $51.29 billion to $57.37 billion in 2025, reflecting an 11.9% compound annual growth rate during this time; this earlier growth trajectory was fueled by several key factors, namely the rising need for biological drugs and their biosimilar counterparts, a greater emphasis placed on treatments tailored to individuals, augmented production volumes of biopharmaceutical agents, and a growing requirement for cell culture techniques that offer both scalability and efficacy.

What's the Projected Size of the Global Mammalian Cell Fermentation Technology Market by 2029?
Anticipation points toward significant expansion within the market for mammalian cell fermentation technology over the forthcoming years, projected to reach a valuation of $87.07 billion by 2029, reflecting a steady compound annual growth rate (CAGR) of 11.0%. This forecasted uptrend is fundamentally underpinned by several key factors: a proliferation in the incidence of long-term illnesses, augmented capital injections from global corporations, the escalating rate of complex chronic health conditions, broader implementation of sophisticated bioprocessing methods, heightened funding directed towards discovering new recombinant proteins, and an ever-increasing need for oncology treatments. Concurrently, notable shifts expected to shape this period include progress in cell culture methodologies, refinements in bioreactor architecture, the maturation of cutting-edge bioprocessing systems, the incorporation of multi-omics data integration, and the drive towards automation powered by technology.

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Top Growth Drivers in the Mammalian Cell Fermentation Technology Industry: What's Accelerating the Market?
The escalating need for biologic drugs is anticipated to stimulate expansion within the mammalian cell fermentation technology sector moving ahead. These biologics, which are medical preparations originating from living systems or their constituents, frequently serve in treating conditions like malignancies, immune system dysfunctions, and contagious illnesses. The rising requirement for biologics is bolstered by progress in biotech, their demonstrated efficacy against widespread long-term ailments such as cancer and autoimmune conditions, regulatory clearances obtained, and increased financial commitment toward investigation and development activities. Mammalian cell fermentation methods offer an efficient route for manufacturing intricate biologics, thereby satisfying the increasing need for therapies tailored to individual patients. The inherent scalability, adaptability, and capability to yield superior quality proteins are key factors pushing innovation within the biopharma sector. To illustrate this trend, data from the National Library of Medicine, a US medical resource, indicated that in 2023, the US Food and Drug Administration (FDA) authorized 55 novel medications-comprising 29 new chemical entities and 25 new biological entities-representing a half jump from the 37 authorizations granted the prior year in 2022. Consequently, the intensified requirement for biologic agents is directly fueling the market expansion for bacterial cell fermentation technology.

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What Trends Will Shape the Mammalian Cell Fermentation Technology Market Through 2029 and Beyond?
Leading enterprises within the market for mammalian cell fermentation technologies are concentrating efforts on creating novel techniques, such as mammalian cell cultivation, in order to enhance their standing. Mammalian cell culture serves as an indispensable instrument across diverse sectors, encompassing biomanufacturing, scientific investigation, and restorative medicine, facilitating the creation of medicinal proteins, inoculations, and viable cells or tissue simulations. To illustrate, in June of 2024, Syntegon, a firm based in Germany specializing in biotechnology, introduced its novel Modular Bioprocessing Platform (MBP) at the Achema 2024 event, an apparatus engineered to resolve primary obstacles encountered during biopharmaceutical manufacturing. This cutting-edge platform presents a solution that is exceptionally adaptable, completely integrated, and automated, appropriate for a spectrum of uses spanning microbial and mammalian cell cultivation, proteins, peptides, nucleic acid strands (oligonucleotides), circular DNA (plasmid DNA), and genetically engineered vaccines. The step-wise configuration of the MBP permits quicker delivery schedules and lower expenditures, all while sustaining superior performance and grade, consistent with premium German engineering principles. By situating all supplementary hardware external to the sterile environment, the platform's prefabricated cleanroom architecture boosts operational efficiency and streamlines upkeep procedures.

What Are the Main Segments in the Mammalian Cell Fermentation Technology Market?
The mammalian cell fermentation technologymarket covered in this report is segmented -

1) By Type: Chinese Hamster ovary* Cell Fermentation; Human Embryonic Kidney Cell Fermentation; Baby Hamster Kidney Cell Fermentation; Murine Myeloma Cell Fermentation; Other Types
2) By Application: Monoclonal Antibodies; Recombinant Proteins; Vaccines; Hormones; Enzymes; Other Applications
3) By End-Use: Biopharmaceutical Companies; Contract Research Organizations And Contract Development and Manufacturing Organizations; Academic And Research Institutes

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Which Top Companies are Driving Growth in the Mammalian Cell Fermentation Technology Market?
Major companies operating in the mammalian cell fermentation technology market are AbbVie Inc., Thermo Fisher Scientific Inc, AstraZeneca PLC, Roche Holdings Inc., Merck KGaA, AGC Group, Lonza Group Ltd., Boehringer Ingelheim GmbH, Catalent Inc., Sartorius AG, Samsung Biologics Co. Ltd., WuXi Biologics, Biocon Limited, Eppendorf AG, KBI Biopharma Inc., Fujifilm Diosynth Biotechnologies, Avid Bioservices Inc., BiOZEEN, Nordmark Pharma GmbH, Scorpius BioManufacturing Inc

Which Regions Will Dominate the Mammalian Cell Fermentation Technology Market Through 2029?
North America was the largest region in the mammalian cell fermentation technology market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the mammalian cell fermentation technology market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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