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Emerging Trends to Reshape the Global Macular Degeneration Treatment Market: Biosimilar Advancements in Age-Related Macular Degeneration (AMD) Treatment: FDA Approvals for Yesafili and Opuviz as a Key Influencer

11-17-2025 09:19 AM CET | Health & Medicine

Press release from: The Business Research Company

Macular Degeneration Treatment

Macular Degeneration Treatment

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Macular Degeneration Treatment Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
The market encompassing treatments for macular degeneration has seen substantial expansion lately; specifically, its valuation is projected to escalate from $11.05 billion in 2024 to $12.38 billion by 2025, reflecting a compound annual growth rate (CAGR) of 12.0%. This upward trajectory throughout the past period stems from several factors, including the demographic shift towards an older populace, modifications in daily living habits, the scarcity of available therapeutic choices, increased public understanding of the condition, and advancements in medical infrastructure.

Macular Degeneration Treatment Market Size Forecast: What's the Projected Valuation by 2029?
Anticipated in the coming years is a period of swift expansion for the market dealing with macular degeneration treatments, projecting a valuation of $18.87 billion by 2029, fueled by a compound annual growth rate calculated at 11.1%. Elevations in research discoveries, greater spending on healthcare services, an escalating prevalence of the condition, the adoption of tailored medical strategies, and worldwide campaigns dedicated to visual wellness are all factors credited with driving this surge throughout the projection timeframe. Key developments characterizing this era will encompass a concentrated effort on therapies involving neural protection and tissue regeneration, the broader deployment of remote patient monitoring and virtual consultation methods, the continued iteration of individualized patient care plans, ongoing exploration into stem cell-based treatments, and consumer-centric programs designed to boost public knowledge and understanding.

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What Are the Drivers Transforming the Macular Degeneration Treatment Market?
Escalating prevalence of afflictions concerning the retina is anticipated to stimulate expansion within the market dedicated to treating macular degeneration. These ocular conditions compromise essential visual structures, thereby impeding the brain's ability to interpret sight accurately, frequently resulting in visual distortions or complete loss of sight. To illustrate the scale of this issue, data from the American Academy of Ophthalmology suggests that the United States populace grappling with primary open-angle glaucoma-an umbrella term for several eye conditions-is projected to reach approximately 7.32 million individuals by the year 2050, with peak incidence observed in those between 70 and 79 years old (accounting for 32% of cases), with women comprising 50% of the affected group, and Hispanics also representing 50% of the caseload; specifically, Hispanic males constitute the largest segment within this demographic breakdown. Consequently, the rising impact of retinal diseases is acting as a key catalyst behind the momentum seen in the market for macular degeneration interventions.

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What Long-Term Trends Will Define the Future of the Macular Degeneration Treatment Market?
A primary strategy among key players in the macular degeneration therapeutic sector involves creating biosimilar alternatives for age-related macular degeneration (AMD) treatment, aiming to broaden access to proven medical interventions. These biosimilars constitute biological medical articles substantially equivalent to a previously licensed originator product, exhibiting no clinically significant variations regarding their safety profile, purity levels, or potency. Illustratively, in May of 2024, the US Food and Drug Administration granted authorizations for Yesafili and Opuviz, a pair of novel biosimilars developed by Biocon Biologics Ltd from India and Samsung Bioepis Co. Ltd based in South Korea. Functionally, both authorized treatments achieve their therapeutic effect by blocking vascular endothelial growth factor (VEGF), the substance driving aberrant blood vessel proliferation within the eye, thereby working to avert vision deterioration linked to issues such as AMD and retinopathy associated with diabetes. The regulatory validation by the FDA followed extensive comparative research demonstrating that Yesafili and Opuviz match Eylea concerning both effectiveness and safety without presenting notable disparities, a conclusion reached after thorough evaluation of the biosimilars' drug absorption patterns and immune responses.

Which Segments in the Macular Degeneration Treatment Market Offer the Most Profit Potential?
The macular degeneration treatmentmarket covered in this report is segmented -

1) By Stage of Disease: Early-Stage AMD; Intermediate AMD; Late-Stage AMD
2) By End User: Ambulatory Surgical Centers; Ophthalmic Clinics; Hospitals
3) By Route of Administration: Oral; Injectable; Other Route of Administration
4) By Types: Wet Macular Degeneration, Dry Macular Degeneration

Subsegments:
1) By Early-Stage AMD: Nutritional Supplements; Lifestyle Modification Treatments
2) By Intermediate AMD: Anti-VEGF Injections; Photodynamic Therapy
3) By Late-Stage AMD: Surgical Treatments; Advanced Anti-VEGF Therapies; Gene Therapy Options

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Which Firms Dominate the Macular Degeneration Treatment Market by Market Share and Revenue in 2025?
Major companies operating in the macular degeneration treatment market include Pfizer Inc., F. Hoffmann-La Roche Ltd., Allergan Inc., Bayer AG, Novartis AG, GlaxoSmithKline plc, Panoptica, Regeneron Pharmaceuticals Inc., Bausch Health Companies Inc., Santen Pharmaceuticals, Aerie Pharmaceuticals Inc., BioXcel Therapeutics Inc., Regenxbio Inc., Spark Therapeutics Inc., Alimera Sciences Inc., Applied Genetic Technologies Corp (AGTC), Cell Medica Ltd., Ophthotech Corporation, Adverum Biotechnologies Inc., Neurotech Pharmaceuticals Inc., 4D Molecular Therapeutics Inc., GenSight Biologics Inc.

Which Regions Offer the Highest Growth Potential in the Macular Degeneration Treatment Market?
North America was the largest region in the macular degeneration treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the macular degeneration treatment Market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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