United States Closed System Transfer Devices Market 2025 | Growth Drivers, Key Players & Investment Opportunities

Market Size and Growth

The Global Closed System Transfer Devices (CSTD) market reached US$ 718.29 million in 2024 and is expected to reach US$ 1968.26 million by 2033, growing at a CAGR of 11.7% during the forecast period 2025-2033.

Key Development:

✅ In May 2025, EQUASHIELD was ranked as the #1 CSTD used in U.S. pharmacies for the seventh consecutive year by an industry publication, highlighting its market leadership in the U.S. hazardous‐drug handling segment.

✅ The National Institute for Occupational Safety and Health (NIOSH) reaffirmed that CSTDs must mechanically prevent the release of hazardous-drug vapors, aerosols, or droplets during preparation and administration in healthcare settings, reflecting renewed emphasis on occupational safety.

✅ A 2025 peer-reviewed study analysed cytotoxic drug vapor release over 28 days and found that even ambient-temperature storage can still pose vapor exposure risks, underscoring the need for CSTDs with improved barrier technologies.

✅ Industry trend reports highlight that CSTDs are increasingly being designed for automation and integration with robotic compounding systems, data traceability, and universal compatibility with vials, syringes, and tubing sets.

✅ Regulatory guidance such as USP continues to drive demand for CSTDs in hazardous-drug compounding and administration, with more healthcare facilities incorporating such devices into standard practice for oncology and infusion services.

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Key Players:

=> Becton, Dickinson and Company, ICU Medical, Inc., EQUASHIELD, B. Braun SE, Yukon Medical, Simplivia Healthcare, LLC, JMS Co.Ltd., West Pharmaceutical Services, Inc, Cormed., and Epic Medical among others.

Growth Forecast Projected:

The Global Closed System Transfer Devices Market is anticipated to rise at a considerable rate during the forecast period, between 2025 and 2033. In 2024, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Closed System Transfer Devices Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

➥ By Product Type: Membrane-to-Membrane Systems, Needleless Systems

➥ By Component: Vial Access Devices, Syringe Safety Devices, Bag Spikes, Male and Female Luer Components

➥ By Closing Mechanism: Click-to-Lock Systems, Luer-Lock Systems, Push-to-Turn, Color-to-Color Systems

➥ By Technology: Diaphragm-Based Devices, Air Filtration Devices

➥ By End-User: Hospitals, Clinics, Others

Regional Analysis for Closed System Transfer Devices Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Closed System Transfer Devices producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Closed System Transfer Devices revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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FAQ

What is the current size of the Closed System Transfer Devices Market?

A: In 2024, the Closed System Transfer Devices Market was valued at US$ 718.29 million , reflecting its strong industry presence.

Q2: How large is the Closed System Transfer Devices Market expected to be by 2033?

A: By 2033, industry forecasts suggest the Closed System Transfer Devices Market will grow to around US$ 1968.26 million, demonstrating significant expansion.

Q3: What is the growth rate of the Closed System Transfer Devices Market?

A: The market is projected to expand at a compound annual growth rate (CAGR) of 11.7% during the forecast period from 2025 to 2033.

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