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In Silico Clinical Trials Market on Track for Strong Growth, Estimated to Grow at 10.3% CAGR Through 2029

10-17-2025 06:21 AM CET | IT, New Media & Software

Press release from: The Business Research Company

In Silico Clinical Trials Market

In Silico Clinical Trials Market

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What Is the Expected CAGR for the In Silico Clinical Trials Market Through 2025?
The market size of in silico clinical trials has notably expanded in the past few years. Projected figures suggest an increase from $3.51 billion in 2024 to $3.74 billion in 2025, with a compound annual growth rate (CAGR) of 6.4%. The historical growth of this market is linked to several factors such as the growing availability of medical data, changes in regulatory structures for virtual trials, advancements in computing power, the rise of digital healthcare, and the broadening initiatives in precision medicine.

What's the Projected Size of the Global In Silico Clinical Trials Market by 2029?
The market size of in silico clinical trials is predicted to experience swift expansion in the coming years, with an expected valuation of $5.54 billion in 2029, and a Compound Annual Growth Rate (CAGR) of 10.3%. The anticipated growth within this period is due to a rising need for quicker drug development procedures, the implementation of virtual patient groups in clinical trials, the proliferation of digital twin technologies, and an upswing in regulatory approval for in silico trials. Prime trends in the forecast period are the creation of more accurate virtual patient models, incorporation of real-world evidence in in silico tests, focus on decentralized and patient-centric trial plans, an increase in the application of digital biomarkers, and greater emphasis on custom-made medicine in virtual trials.

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Top Growth Drivers in the In Silico Clinical Trials Industry: What's Accelerating the Market?
The increase in the occurrence of infectious diseases is projected to drive the advancement of the in silico clinical trials market. This increase is fueled by factors such as urbanization, overcrowding, climate change, microbial evolution, and heightened travel activities. In silico clinical trials utilize computational models and simulations to hasten the process of developing treatments for infectious diseases. This allows scientists to study disease mechanisms, predict the effectiveness of drugs, and enhance the design of clinical trials, thereby improving patient results and boosting public health initiatives. For instance, data from gov.uk, a public sector information site in the UK, indicates that new HIV diagnoses in England rose to 3,805 cases in 2022, a 22% upsurge from the 3,118 cases documented in 2021, and a 26% increase from the 3,026 cases logged in 2020. Thus, the escalating occurrence of infectious diseases is augmenting the in silico clinical trials market.

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What Trends Will Shape the In Silico Clinical Trials Market Through 2029 and Beyond?
One of the main trends gaining traction in the in silico clinical trials sector is the formation of strategic alliances. Notable companies in this industry are engaging in partnerships to reinforce their market dominance. For example, in March 2023, Premier Research, a clinical research organization from the US, joined forces with InSilicoTrials, a US-based firm specializing in modelling and simulation for drug development. This collaboration empowers Premier Research to carve out safer, quicker, and more effective routes for obtaining approval for treatments for rare diseases. Additionally, in March 2022, 4P-Pharma, a France-based biotech company in the clinical-stage, allied with QuantHealth, an AI firm from Israel. They aim to conduct patient-focused drug simulations to speed up and lower the risk in drug development. This cooperation enables 4P-Pharma to conduct in silico clinical trials of their leading drug candidates and expedite clinical trial simulations using extensive molecular drug data and real-world data (RWD).

What Are the Main Segments in the In Silico Clinical Trials Market?
The in silico clinical trialsmarket covered in this report is segmented -

1) By Phase: Phase I, Phase II, Phase III, Phase IV
2) By Therapeutic Area: Oncology, Infectious Disease, Hematology, Cardiology, Dermatology, Neurology, Diabetes, Other Therapeutic Areas
3) By Industry: Medical Devices, Pharmaceutical

Subsegments:
1) By Phase I: Safety And Dosage Trials, Pharmacokinetics And Pharmacodynamics Studies
2) By Phase II: Efficacy Trials, Dose-Response Studies
3) By Phase III: Comparative Effectiveness Trials, Large-Scale Efficacy Studies
4) By Phase IV: Post-Marketing Surveillance, Long-Term Safety Studies

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Which Top Companies are Driving Growth in the In Silico Clinical Trials Market?
Major companies operating in the in silico clinical trials market include Dassault Systemes SE, Clarivate plc, Evotec A.G, Evidera, Certara Inc., Abzena Limited, Selvita, Simulations Plus Inc., Insilico Medicine Inc., AnyLogic Company, Biomax Informatics, GNS Healthcare Inc., 4P-Pharma, Nuventra Pharma Sciences, Archimedes, Novadiscovery Sas, Rosa & Co., In Silico Biosciences, Leadscope, Biognos Ab, BioNova, Immunetrics Inc., InSilicoTrials, Physiomics plc, InhibOx, Entelos

Which Regions Will Dominate the In Silico Clinical Trials Market Through 2029?
North America was the largest region in the in silico clinical trials market in 2024. Asia-Pacific is expected to be the fastest-growing region in the in silico clinical trials market report during the forecast period. The regions covered in the in silico clinical trials market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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