United States Minimally Invasive Spine Surgery Market 2025 | Growth Drivers, Competitive Landscape & Investment Opportunities

Market Size and Growth

The Global Minimally Invasive Spine Surgery Market reached USD 2,679.8 million in 2022 and is expected to reach USD 4,164.4 million by 2031, and is expected to grow with a CAGR of 5.8% during the forecast period 2024-2031.

Key Development:

United States: Recent Industry Developments

✅ In October 2025, Convatec revealed plans to invest over $1 billion in expanding its R&D facilities in Boston, U.S., by 50% by the end of the year. This expansion underscores the company's commitment to advancing spinal care technologies.

✅ In August 2025, Medtronic introduced a new robotic-assisted spine surgery system, expanding its MISS portfolio. This addition aims to improve surgical precision and patient outcomes in spinal procedures.

✅ In July 2025, Orthofix announced the full U.S. commercial launch of the ReefL Interbody System for lateral lumbar fusion procedures. This innovative system enhances surgical precision and patient outcomes in minimally invasive spine surgery.

Recent Mergers and acquisitions:

United States: Recent M&A / Industry Moves
✅ In September 2025, Highridge Medical acquired the FlareHawk® and ToroTM expandable interbody fusion systems, along with the LineSider® pedicle screw system, from Accelus. The deal strengthens Highridge's spinal implant portfolio and enhances its focus on innovation in minimally invasive spine surgery.

✅ In April 2025, Viscogliosi Brothers, LLC completed the acquisition of Stryker's U.S. spine business, forming a new company called VB Spine, LLC. The transaction includes spinal implants and provides access to advanced robotic tools like Mako Spine and Copilot.

✅ In April 2025, Globus Medical finalized its acquisition of Nevro Corp., expanding into chronic pain and sacroiliac joint treatment technologies that complement its minimally invasive spine solutions.

✅ In April 2025, Wellspring Capital Management, in partnership with MSouth Equity Partners, acquired Summit Spine & Joint Centers, a leading provider of minimally invasive spine and pain management services in the southeastern United States.

Other Regions: Recent M&A and Strategic Deals

✅ In September 2025, Highridge Medical acquired innovative spine surgery products from Accelus, including the FlareHawk® and ToroTM expandable interbody fusion systems and the LineSider® pedicle screw system. The deal strengthens Highridge's minimally invasive lumbar spine portfolio.

✅ In August 2025, Globus Medical completed the acquisition of Nevro Corp for approximately US$250 million. The acquisition adds spinal cord stimulation and pain management technologies to Globus's spine solutions portfolio.

✅ On January 28, 2025, Stryker agreed to sell its U.S. spinal implants business to Viscogliosi Brothers, forming a new company named VB Spine. The transaction includes related operations in France and aligns with Stryker's strategy to focus on advanced surgical technologies.

✅ In 2025, Medtronic acquired the intellectual property rights for OsteoSync titanium pad technology from Nanovis. This deal supports Medtronic's innovation in next-generation PEEK interbody fusion devices.

✅ In 2025, Stryker increased its ownership stake to a controlling share in VEXIM, a French firm specializing in minimally invasive vertebral fracture treatments, notably the SpineJack® system. This move enhances Stryker's leadership in vertebral augmentation.

✅ In 2025, Amendia acquired Spinal Elements, expanding its spinal implants and instrumentation portfolio. The acquisition strengthens Amendia's position in the global spine surgery market.

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Minimally Invasive Spine Surgery (MISS) uses advanced techniques and specialized instruments to treat spinal disorders through small incisions. It reduces tissue damage, lowers recovery time, minimizes pain, and improves patient outcomes compared to traditional spine surgery.

Key Players:

=> Zimmer Biomet, DePuy Synthes (Johnson & Johnson), Stryker, Medtronic, Aesculap, Inc. (B. Braun Company), Alliance Spine, NuVasive Inc., Bioventus, Integra LifeSciences, and Globus Medical among others.

Growth Forecast Projected:

The Global Minimally Invasive Spine Surgery Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Minimally Invasive Spine Surgery Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

➥ By Product Type: Instrumentation, Devices

➥ By Application: Non-fusion Surgery, Fusion Surgery

➥ By End-User: Hospitals, Ambulatory Surgical Centers, Others

Regional Analysis for Minimally Invasive Spine Surgery Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Minimally Invasive Spine Surgery producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Minimally Invasive Spine Surgery revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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FAQ

What is the current size of the Minimally Invasive Spine Surgery Market?

A: In 2022, the Minimally Invasive Spine Surgery Market was valued at USD 2,679.8 million, reflecting its strong industry presence.

Q2: How large is the Minimally Invasive Spine Surgery Market expected to be by 2031?

A: By 2031, industry forecasts suggest the Minimally Invasive Spine Surgery Market will grow to around USD 4,164.4 million, demonstrating significant expansion.

Q3: What is the growth rate of the Minimally Invasive Spine Surgery Market?

A: The market is projected to expand at a compound annual growth rate (CAGR) of 5.8% during the forecast period from 2024 to 2031.

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