Press release
US Cancer Biomarkers Market to Surpass USD 11.2 Billion by 2030, Driven by Liquid Biopsies and AI-Enabled Diagnostics
United States Cancer Biomarkers Market
Breast cancer dominates with 36.33% market share, while prostate cancer is projected to grow fast at 9.02% CAGR through 2030. On the technology front, protein biomarkers maintain leadership with over 50% contribution, while genetic biomarkers are emerging as the fastest-growing category, supported by advancements in multi-omic profiling and liquid biopsy adoption. The Sun Belt states-namely Texas, Florida, and Arizona-exhibit stronger demand growth, driven by their aging populations and improved state-level coverage mandates for biomarker testing.
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Key Highlights from the Report
➤ United States cancer biomarkers market projected to grow from USD 7.62 billion in 2025 to USD 11.23 billion by 2030 at an 8.06% CAGR.
➤ Breast cancer leads the disease segmentation; prostate biomarkers expected to grow fastest.
➤ Protein biomarkers dominate revenue while genetic biomarkers grow rapidly with falling sequencing costs.
➤ Omics technologies lead profiling, while immunoassays gain traction in mid-tier hospital settings.
➤ Federal Cancer Moonshot funding boosts R&D in minimally invasive detection and early diagnosis.
➤ Clinical laboratories show strongest growth due to centralized genomic analysis and cost efficiencies.
Market Segmentation
By disease type, breast cancer accounts for the largest market share due to widespread use of HER2, ER, and multi-gene assays, while prostate cancer biomarkers such as MyProstateScore 2.0 are expected to experience rapid adoption due to their non-invasive nature.
By biomolecule type, protein biomarkers held 50.41% market share in 2024, driven by established immunoassay integration in hospital workflows. Genetic biomarkers are advancing quickest at a 9.11% CAGR as high-plex sequencing becomes more affordable. Emerging RNA and methylation biomarkers further extend early detection windows and precision therapy alignment.
By profiling technology, omics platforms captured 33.58% revenue in 2024, offering comprehensive molecular characterization, while immunoassays grow at 8.96% CAGR with adoption of automation and microfluidic devices.
By end user, hospitals and clinics held a 43.44% share in 2024, though clinical and reference laboratories are growing fastest due to expertise in genomic data interpretation and economies of scale. Pharmaceutical partnerships for clinical trials and companion diagnostics also strengthen this segment.
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Regional Insights
The market demonstrates regional variances reflecting cancer incidence and access to biomarker testing. Leading academic centers along the East and West Coasts spearhead diagnostic innovations, while access gaps persist in the Midwest and rural regions. Only 36.6% of the population lives within one hour of a National Cancer Institute-designated facility.
Seventeen states have enacted biomarker coverage mandates, boosting reimbursement rates and enabling broader clinical adoption. The Sun Belt states continue to lead revenue growth as older demographics show higher testing demand. Telehealth-enabled testing and at-home sample collection are expanding rural penetration, helped by broadband connectivity and public-health grants from the Cancer Moonshot initiative.
Market Dynamics
Market Drivers
Rising cancer incidence, aging demographics, and national precision medicine initiatives are accelerating biomarker adoption. Government funding programs and regulatory clarity have encouraged commercial development, while hospital systems are centralizing genomic laboratories for rapid turnaround testing.
Market Restraints
High diagnostic costs, payer variability, and multi-agency regulatory compliance remain key challenges hindering technology uptake, especially in rural or underinsured settings. Smaller labs struggle to absorb compliance costs under the FDA's updated LDT framework.
Market Opportunities
Emerging opportunities lie in AI-enabled multi-omic testing, liquid biopsy expansion, and modular assay systems that integrate genetic and protein biomarkers. Public-private funding partnerships continue to lower technology costs, broadening access to biomarker-based cancer care.
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Reasons to Buy the Report
✔ In-depth forecast of market size, CAGR, and segment-wise growth through 2030.
✔ Insights on regulatory shifts including FDA, CMS, and state-level coverage mandates.
✔ Segmentation analysis by disease type, biomolecule, technology, and end-user category.
✔ Evaluation of innovation trends such as AI, multi-omics, and liquid biopsy technologies.
✔ Profiles of leading US cancer biomarker companies and recent industry advancements.
Frequently Asked Questions (FAQs)
◆ How big is the United States cancer biomarkers market in 2025 and what is the forecast through 2030?
◆ Which cancer type contributes the largest share to the US biomarker market?
◆ What technologies are driving the growth of cancer biomarkers in the United States?
◆ Who are the leading players in the United States cancer biomarkers market?
◆ Which states and regions are driving the highest adoption rates of biomarker testing?
Company Insights
Abbott Laboratories Inc.
Thermo Fisher Scientific
Biomerieux
Illumina Inc.
F. Hoffmann-La Roche Ltd
Recent Developments:
June 2025: Mainz Biomed commenced the next phase of PancAlert blood test trials targeting early pancreatic cancer detection.
June 2025: Guardant Health received FDA Breakthrough Device designation for its Shield multi-cancer detection test with 98.6% specificity.
April 2025: Roche announced a USD 50 billion investment in US diagnostics and genetic therapy capacity expansion.
Conclusion
The United States cancer biomarkers market is on course for robust expansion through 2030, fueled by technological innovation, policy support, and precision medicine uptake. With liquid biopsy platforms improving patient experience and AI-powered analytics optimizing detection, cancer diagnostics are entering a more scalable and accessible era. Sustained investment from federal initiatives and public-private collaboration will continue to drive test adoption, reduce mortality disparities, and make biomarker-driven treatment an integral component of American oncology care.
Contact Us
Mr. Sai Kiran
DataM Intelligence 4market Research LLP Ground floor
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Uppal, Hyderabad, Telangana 500039
USA: +1 877-441-4866
Email: Sai.k@datamintelligence.com
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About Us
DataM Intelligence 4Market Research is a comprehensive market intelligence platform offering syndicated and customized reports along with expert consulting across multiple industries, including chemicals, healthcare, agriculture, food & beverages, and more. With extensive experience and a strategy-focused approach, DataM provides businesses and individuals with reliable market insights, statistical forecasts, and personalized research solutions to help them make informed decisions and successfully bring innovations to market.
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