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United States Prurigo Nodularis Treatment Market 2025 | Growth Drivers, Key Players & Investment Opportunities

10-13-2025 08:34 AM CET | Health & Medicine

Press release from: DataM intelligence 4 Market Research LLP

Prurigo Nodularis Treatment Market

Prurigo Nodularis Treatment Market

Market Size and Growth

The global prurigo nodularis treatment market was valued at US$ 1.28 Billion in 2023. The market size reached US$ 1.34 Billion in 2024 and is expected to reach US$ 1.99 Billion by 2033, growing at a CAGR of 4.2% during the forecast period 2025-2033.

Key Development:

✅ In February 2025, the Medicines and Healthcare products Regulatory Agency (MHRA), the UK's medicines regulator, granted marketing authorisation for nemolizumab (brand name Nemluvio) for two major skin conditions: moderate-to-severe prurigo nodularis in adults and moderate-to-severe atopic dermatitis (eczema) in both adolescents (aged 12 and older, weighing at least 30 kg) and adults.

✅ In September 2024, Amber Specialty Pharmacy announced the availability of Galderma's latest medication, NEMLUVIO (nemolizumab-ilto), for the treatment of Prurigo Nodularis in adults. This partnership marks a significant advancement in the therapeutic options available to patients suffering from this chronic, debilitating skin condition.

✅ In March 2024, Incyte announced new clinical results for its investigational drug, povorcitinib (INCB54707), an oral JAK1 inhibitor. The results come from a Phase 2 clinical trial assessing the drug's effectiveness and safety in adult patients with prurigo nodularis (PN).

✅ In February 2024, Galderma announced that the U.S. Food and Drug Administration (FDA) had accepted its Biologics License Applications for nemolizumab, intended for the treatment of prurigo nodularis as well as moderate to severe atopic dermatitis in both adolescents and adults. Nemolizumab is a first-in-class investigational monoclonal antibody engineered to block IL-31 signaling, offering safe and rapid relief from the most troublesome symptom associated with both conditions: persistent itch.

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Prurigo nodularis treatments are therapies aimed at managing chronic, itchy skin nodules caused by persistent scratching. They include topical corticosteroids, immunomodulators, antihistamines, and emerging biologics, focusing on reducing inflammation, controlling itch, and improving patient quality of life.

Recent Mergers and acquisitions:

United States: Recent Mergers & Acquisitions

✅ May 28, 2025 - Johnson & Johnson acquired rights to Numab Therapeutics' experimental eczema treatment, NM26, for approximately $1.25 billion. This bi-specific antibody drug targets dual disease pathways and recently completed early-stage trials.

✅ May 12, 2025 - Johnson & Johnson announced plans to acquire Proteologix for $850 million. Proteologix's PX128 antibody is set to begin early-stage development for moderate to severe atopic dermatitis and asthma.

✅ December 2022 - MyHealthTeam partnered with Arcutis Biotherapeutics to launch MySebDermTeam, a social network aimed at supporting individuals with seborrheic dermatitis. This collaboration addresses challenges like underdiagnosis and lack of accessible information.

Japan: Recent Mergers & Acquisitions

✅ March 26, 2025 - Maruho acquired the world's first manufacturing and marketing approval for Mitchga® (nemolizumab) Subcutaneous Injection 60mg Syringes for the treatment of pruritus associated with atopic dermatitis in adults and children over 13 years old in Japan.

Key Players:

=> The major global players in the prurigo nodularis treatment market include Sanofi and Regeneron Pharmaceuticals, Inc., Galderma, Teva Pharmaceuticals USA, Inc., Glenmark Pharmaceuticals Inc., USA, LEO Pharma, GSK plc., Abbott, and Bristol Myers Squibb company. Among others.

Emerging Players:

=> The emerging players in the prurigo nodularis treatment market include BeiGene, Celldex Therapeutics, Incyte Corporation, Guangdong Hengrui Pharmaceutical Co., Ltd, Keymed Biosciences Co., Ltd, and Amgen, among others.

Growth Forecast Projected:

The Global Prurigo Nodularis Treatment Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Prurigo Nodularis Treatment Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

➥ By Treatment Type: Monoclonal Antibodies, Calcineurin Inhibitor, Vitamin D Analog, Corticosteroid, Immunomodulatory Drugs (IMiDs), Antihistamines, Others
➥ By Route of Administration: Parenteral, Topical, Oral
➥ By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Regional Analysis for Prurigo Nodularis Treatment Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Prurigo Nodularis Treatment producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Prurigo Nodularis Treatment revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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FAQ

What is the current size of the Prurigo Nodularis Treatment Market?

A: In 2023, the Prurigo Nodularis Treatment Market was valued at US$ 1.34 Billion, reflecting its strong industry presence.

Q2: How large is the Prurigo Nodularis Treatment Market expected to be by 2033?

A: By 2033, industry forecasts suggest the Prurigo Nodularis Treatment Market will grow to around US$ 1.99 Billion, demonstrating significant expansion.

Q3: What is the growth rate of the Prurigo Nodularis Treatment Market?

A: The market is projected to expand at a compound annual growth rate (CAGR) of 4.2% during the forecast period from 2025 to 2033.

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About Us -

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