United States Therapeutic Hypothermia Market 2025 | Growth Drivers, Key Players & Investment Opportunities

Market Size and Growth

The Global Therapeutic Hypothermia Market reached US$ 288 million in 2023 and is expected to reach US$ 458.11 million by 2031, growing at a CAGR of 6.1% during the forecast period 2024-2031.

Key Development:

United States: Recent Industry Developments

✅ In July 2025, a U.S.-based neonatal intensive care unit (NICU) increased the percentage of inborn infants with moderate or severe hypoxic-ischemic encephalopathy (HIE) who received therapeutic hypothermia (TH) initiated before 3 hours from 25% to 79%. This improvement was achieved through enhanced multidisciplinary education, elimination of time delays, and early identification of eligible infants.

✅ In June 2025, a regional transport service successfully introduced servo-controlled TH for infants with HIE. The initiative aimed to compare the time to reach the target temperature of 33-34°C, enhancing efficiency and safety during transport.

✅ In May 2025, ReAlta Life Sciences presented new clinical data from its ongoing HIE research, including inflammatory biomarkers and pharmacokinetic data from its Phase 2 STAR trial in newborns, highlighting advancements in TH-related therapies.

Japan: Recent Industry Developments

✅ In July 2025, Japanese researchers evaluated the introduction of servo-controlled TH by a regional transport service and referring centers for infants with HIE. The study focused on reducing the time to reach the target temperature of 33-34°C, aiming to improve neonatal care efficiency.

✅ In June 2025, a Japanese hospital reported a significant increase in the percentage of inborn infants with moderate or severe HIE who received TH initiated before 3 hours, achieved through multidisciplinary education, time-delay elimination, and early identification of eligible infants.

✅ In May 2025, a Japanese medical device company launched an advanced TH system for neonatal care, featuring improved temperature control and monitoring to enhance the safety and efficacy of treatments for infants with HIE.

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Therapeutic hypothermia is a medical treatment that lowers a patient's body temperature to reduce tissue damage after events like cardiac arrest or traumatic brain injury. It helps protect the brain and vital organs, improving survival rates and neurological outcomes.

Key Players:

=> Asahi Kasei Corporation, Becton Dickinson and Company, Shenzhen Comen Medical Instruments Co., Terumo Cardiovascular Systems Corporation, Phoenix Medical Systems, Gentherm Medicals, International Biomedical Ltd., Global Healthcare SG, Stryker Corporation, Aspen Systems among others.

Growth Forecast Projected:

The Global Therapeutic Hypothermia Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Therapeutic Hypothermia Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

➥ By Product Type: Surface Cooling Packs, Surface Heat Exchange Device, Surface Cooling Helmet, Catheter Technology, Cold Fluids Infusion, Others
➥ By Application: Neurology, Cardiology, Neo-Natal Care
➥ By End User: Hospitals, Specialty Clinics, Ambulance & Emergency Medical Services, Academic & Research Institutes, Others

Regional Analysis for Therapeutic Hypothermia Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Therapeutic Hypothermia producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Therapeutic Hypothermia revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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FAQ

What is the current size of the Therapeutic Hypothermia Market?

A: In 2023, the Therapeutic Hypothermia Market was valued at US$ 288 million, reflecting its strong industry presence.

Q2: How large is the Therapeutic Hypothermia Market expected to be by 2031?

A: By 2031, industry forecasts suggest the Therapeutic Hypothermia Market will grow to around US$ 458.11 million, demonstrating significant expansion.

Q3: What is the growth rate of the Therapeutic Hypothermia Market?

A: The market is projected to expand at a compound annual growth rate (CAGR) of 6.1% during the forecast period from 2024 to 2031.

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