Breakthrough Clinical Study Shows AI-Powered Music Therapy Platform Dramatically Reduces Chemotherapy Symptoms in Breast Cancer Patients

Mumbai-based Skitii Platform Achieves 55% Pain Reduction and 50% Decrease in Nausea Through Real-Time Emotion Detection and Personalized Music Adaptation
MUMBAI, INDIA - September 27, 2025 - A groundbreaking clinical trial has demonstrated that emotion-adaptive music therapy delivered through the Skitii platform significantly improves quality of life for breast cancer patients undergoing chemotherapy. The study, published in the International Journal of Advance Research Publication and Reviews, reports unprecedented improvements in pain tolerance, nausea reduction, and emotional wellbeing through the integration of artificial intelligence, computer vision, and heart rate variability biofeedback.
The controlled clinical trial, conducted by Mindful Gurukul Private Limited, evaluated 30 post-mastectomy breast cancer patients over an 8-week period. Participants using the Skitii platform experienced:

55% improvement in pain tolerance - exceeding the effectiveness of many pharmaceutical interventions
50% reduction in chemotherapy-induced nausea - addressing a critical unmet need in cancer care
47% enhancement in emotional regulation capacity - supporting mental health during treatment
46% improvement in sleep quality - crucial for recovery and healing

Revolutionary Technology Meets Ancient Healing
The Skitii platform represents a paradigm shift in supportive cancer care by combining real-time facial emotion recognition (achieving 94.8% accuracy) with continuous heart rate variability monitoring to deliver personalized musical interventions that adapt moment-by-moment to each patient's emotional and physiological state.
"Traditional music therapy uses a one-size-fits-all approach that doesn't account for patients' changing needs throughout their treatment journey," explained Dr. Chirag Jain, Chief Medical Officer at Mindful Gurukul and lead investigator. "Our platform detects subtle emotional shifts and physiological stress markers, then immediately adjusts the musical parameters - tempo, key, instrumentation - to provide optimal therapeutic benefit."
Addressing Critical Gaps in Cancer Care
Despite advances in cancer treatment, 70-85% of chemotherapy patients experience moderate to severe pain, while 60-80% report significant nausea even with standard medications. The emotional toll is equally significant, with up to 90% experiencing anxiety and emotional dysregulation during treatment.
The study's participants demonstrated remarkable improvements in objective physiological markers, including a 35% increase in heart rate variability parameters associated with stress resilience and a 28% improvement in autonomic nervous system balance. These biological changes validate the therapeutic effects beyond subjective symptom reporting.
Exceptional User Experience and Adherence
Unlike many digital health interventions that struggle with user engagement, the Skitii platform achieved a 93% adherence rate throughout the study. Participants praised the technology's intuitive interface and reported feeling "understood" by the adaptive system. The platform requires just 20 minutes daily - 10 minutes for an energizing morning protocol and 10 minutes for evening relaxation.
"For the first time in my treatment, I felt like something was responding to how I actually felt in that moment, not just following a generic protocol," shared one study participant. "When my anxiety spiked, the music would shift within seconds to help calm me. It was like having a therapeutic companion that truly understood my needs."
Implications for Global Cancer Care
With over 2.3 million new breast cancer cases diagnosed annually worldwide, scalable and effective supportive care interventions are urgently needed. The Skitii platform's digital delivery model enables widespread accessibility without the resource constraints of traditional in-person music therapy.
"This technology could democratize access to evidence-based supportive care," noted Darshana Jain, co-investigator. "A single platform deployment could serve hundreds of patients simultaneously, offering substantial cost-effectiveness advantages while maintaining personalized care quality."
Next Steps and Future Research
The research team is planning multicenter international trials to validate these findings across diverse populations and cancer types. Future developments will explore integration with electronic health records, expansion to other symptom clusters, and incorporation of additional biomarkers for enhanced personalization.
Healthcare providers interested in learning more about implementing the Skitii platform in their oncology programs can visit [contact information would be inserted here].

Study Reference
Jain C, Jain D. Efficacy of Emotion-Adaptive Music Therapy Using the Skitii Platform in Post-Mastectomy Breast Cancer Patients: A Controlled Clinical Study. International Journal of Advance Research Publication and Reviews. 2025;2(9):547-567.

Note: This press release summarizes findings from a peer-reviewed clinical study. Individual results may vary. The Skitii platform is intended as a supportive care intervention and should not replace standard medical treatment.

Mindful Gurukul Private Limited

417, FLOOR-4,B, CHANDRALOK, MANAV MANDIR ROAD, TEEN BATTI, MALABAR HILL, MUMBAI, Mumbai City, Maharashtra
Media Contact:
chiragjain@mindfulgurukul.com

Mindful Gurukul Private Limited is a Mumbai-based digital therapeutics company focused on developing evidence-based, technology-enabled interventions for chronic disease management. The company specializes in integrating artificial intelligence with validated therapeutic modalities to create accessible, personalized healthcare solutions.

This release was published on openPR.