United States Brucellosis Vaccines Market Outlook: Advancements in Subunit, Multi-Epitope, and DIVA Vaccines Enhancing Safety and Efficacy for Livestock and Human Health

Global Brucellosis Vaccines Market was valued at USD 323.45 million in 2021. It is forecasted to reach High by 2031, growing at a CAGR of 4.5% during the forecast period 2024-2031.

The Brucellosis Vaccines Market includes vaccines designed to prevent Brucella infections in livestock and humans. These vaccines help reduce economic losses in agriculture and limit zoonotic transmission. Market growth is driven by increasing awareness of animal and public health, rising livestock farming, and government initiatives for disease control. Veterinary clinics, farms, and pharmaceutical manufacturers are key stakeholders. Research into safer and more effective vaccines continues to enhance market adoption globally.

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☛ Brucellosis Vaccines Market Recent Developments 2025:

A notable advancement is the development of a plant-based subunit vaccine using the Brucella abortus outer membrane protein OMP25, produced in transgenic tobacco plants. This approach aims to offer a low-cost, scalable, and safer vaccine alternative to traditional live-attenuated vaccines, avoiding their safety and efficacy limitations. The OMP25 protein elicits strong immune responses and shows promise in preclinical animal models.

Novel multi-epitope vaccines (MEV) designed using immunoinformatics and reverse vaccinology approaches target multiple Brucella antigens to enhance immunogenicity and protection. Recent in silico studies proposed MEV constructs incorporating multiple T-cell and B-cell epitopes to stimulate broad immunity.

Research efforts also focus on creating vaccines that distinguish infected from vaccinated animals (DIVA), improving vaccine safety, and providing sterile immunity. These goals are part of the international STAR IDAZ roadmap for brucellosis vaccine development, emphasizing better understanding of host-pathogen interactions and advanced delivery systems.

Live Brucella vaccines continue to be used but face challenges due to safety concerns, risk of reversion, and interference with diagnostic assays. Market reports project moderate growth in live vaccine use but highlight a strong shift toward novel subunit and multi-epitope vaccine candidates.

☛ Brucellosis Vaccines Market Trends:

The brucellosis vaccines market is growing due to the rising prevalence of zoonotic infections, particularly in livestock, and increased awareness of public health risks. Government initiatives promoting vaccination programs are supporting market expansion.

Trends include development of safer and more effective live-attenuated and subunit vaccines, increased focus on oral and thermostable formulations for easier administration, and research into cross-protective vaccines to cover multiple Brucella species.

☛ Brucellosis Vaccines Market Competitve Landscape:

AbbVie, Inc., AstraZeneca PLC, Bayer AG, BeiGene, CARsgen Therapeutics, CStone Pharmaceuticals Co., Ltd. and GlaxoSmithKline PLC.

Research Methodology

We follow a hybrid research approach, combining qualitative insights with rigorous quantitative analysis to deliver reliable and comprehensive market intelligence. Our process begins with extensive secondary research, drawing on trusted industry reports, proprietary databases, and credible market sources. This is then reinforced through targeted primary research, including structured surveys and in-depth interviews with industry leaders, subject matter experts, and key market participants.

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☛ Segment Covered in the Brucellosis Vaccines Market:

By Species: Sheep | Cattle | Goat

By Treatment: Antibiotics | Vaccines

By Diagnosis: Serological Tests | Molecular Techniques | Bone Marrow Biopsy | Magnetic Resonance Imaging (MRI) | Others

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☛ Regional Analysis for Brucellosis Vaccines Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

☛ Frequently asked questions:

➠ What is the global sales, production, consumption, import, and export value of the Brucellosis Vaccines Market?
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➠ Which product types or end-users show the most growth potential and market share?
➠ What challenges and constraints are impacting the Brucellosis Vaccines Market?
➠ What sales, marketing, and distribution channels are used globally?

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