The Rise In Arthritis Prevalence The Growth Of The Prescription Pain Medication Market Due To Increasing Obesity And Inflammation: The Driving Engine Behind Prescription Pain Medication Market Evolution in 2025

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Prescription Pain Medication Market Size Growth Forecast: What to Expect by 2025?
The market for prescription pain medication has been consistently expanding in past few years. It's forecasted to increase from $73.59 billion in 2024 to $77.22 billion in 2025 with a CAGR of 4.9%. The historical growth has been a result of the rising occurrence of persistent pain, an increasing number of surgeries, a heightened emphasis on palliative care, and a surge in the number of musculoskeletal disorder cases.

How Will the Prescription Pain Medication Market Size Evolve and Grow by 2029?
Over the subsequent years, the market size for prescription pain medication is anticipated to experience significant growth, reaching a valuation of "$95.11 billion in 2029" with a compound annual growth rate (CAGR) of 5.3%. This substantial growth during the forecast period could be ascribed to factors such as the escalating demand for personalized medicine, an increased emphasis on managing post-traumatic pain, the rising implementation of telemedicine for pain management, an increasing number of patients seeking opioid alternatives, and the growing incidence of neuropathic pain. Parallel to this, prominent future trends comprise the development of non-opioid pain substitutes, incorporation of digital health solutions, advancements in targeted pain therapies, the progression of combination pain medications, and innovative efforts towards non-addictive pain medications.

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What Drivers Are Propelling the Growth of Prescription Pain Medication Market Forward?
The growth of the prescription pain medication market is projected to be driven by the rising prevalence of arthritis. This condition, which involves the inflammation of one or more joints, leads to pain, swelling, stiffness, and a decreased range of movement. The primary contributing factor to the rise in arthritis cases is obesity, due to the additional strain it places on joints, particularly on the knees, resulting in increased inflammation. The administration of prescription pain medication aids in the management of arthritis by relieving inflammation and pain, enhancing joint function, and improving the overall life quality of those afflicted. For instance, data from the Office for Health Improvement and Disparities, a UK government department, reveals that in March 2023, 17.6% of people aged 16 and older had arthritis or a persistent back or joint issue, a rise from 17.0% in 2021. Consequently, the increasing incidence of autoimmune diseases is fueling the expansion of the prescription pain medication market.

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What Are the Key Trends Driving Prescription Pain Medication Market Growth?
Key participants in the prescription pain medication market are concentrating efforts on the creation of alternative treatments, particularly non-opioid analgesics, in response to escalating worries regarding opioid dependency and to enhance patient safety. Non-opioid painkillers are drugs that control pain without exposing patients to the addictive risks associated with opioids, providing a safer and effective solution for sustained pain control while minimizing the chance of addiction and overdose. For example, Vertex Pharmaceuticals Incorporated, an American biotech firm, gained approval from the U.S. Food and Drug Administration (FDA) in January 2025 for their first-of-its-kind non-opioid oral drug, JOURNAVX. This medication uniquely blocks NaV1.8 sodium channels in peripheral nerves, preventing pain signals without involvement of the central nervous system and thereby providing effective relief from acute pain without the risk of addiction. Clinical trials in abdominoplasty and bunionectomy have found that a twice-daily dosage of this medication leads to significant pain reduction. Furthermore, it is not a controlled substance, thus addressing an urgent requirement for safer acute pain treatment methods.

What Are the Key Segments in the Prescription Pain Medication Market?
The prescription pain medication market covered in this report is segmented -

1) By Type: Prescription Non-Steroidal Anti-Inflammatory Drugs, Opioids, Anti-Epileptic Medicines, Antidepressants, Other Types
2) By Route Of Administration: Oral, Injectable, Transdermal, Other Route Of Administrations
3) By Application: Neuropathic Pain, Cancer Pain, Post-Operative Pain, Other Applications
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:
1) By Prescription Non-Steroidal Anti-Inflammatory Drugs: COX-2 Inhibitors, Traditional Non-Steroidal Anti-Inflammatory Drugs, Combination Non-Steroidal Anti-Inflammatory Drugs
2) By Opioids: Strong Opioids, Mild Opioids, Opioid Combination Medications
3) By Anti-Epileptic Medicines: Sodium Channel Blockers, Gamma-Aminobutyric Acid Modulators, Glutamate Inhibitors
4) By Antidepressants: Selective Serotonin Reuptake Inhibitors, Tricyclic Antidepressants, Serotonin-Norepinephrine Reuptake Inhibitors, Other Antidepressants
5) By Other Types: Muscle Relaxants, Topical Pain Medications, Corticosteroids

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Who Are the Key Players Shaping the Prescription Pain Medication Market's Competitive Landscape?
Major companies operating in the prescription pain medication market are Mallinckrodt Public Limited Company, Pfizer Inc., Johnson And Johnson, Merck And Co. Inc., AbbVie Inc., Bayer AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, Novartis International AG, GlaxoSmithKline Public Limited Company, Takeda Pharmaceutical Company Limited, Eli Lilly And Company, Teva Pharmaceutical Industries Ltd., Boehringer Ingelheim GmbH, Mylan N.V., Sandoz, Inc, Bausch Health Companies Inc., Purdue Pharma L.P., Endo International Plc

What Geographic Markets Are Powering Growth in the Prescription Pain Medication Market?
North America was the largest region in the prescription pain medication market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the prescription pain medication market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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