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Surge In Mental Health Disorders Fuels Antidepressant Drug Industry Growth: Powering Innovation and Expansion in the Antidepressants Market by 2025

09-15-2025 11:36 AM CET | Health & Medicine

Press release from: The Business Research Company

Antidepressants Market

Antidepressants Market

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What Is the Expected CAGR for the Antidepressants Market Through 2025?
Over the last few years, the size of the antidepressants market has consistently expanded. It's projected that it will increase from $17.33 billion in 2024 to $17.9 billion in 2025, representing a compound annual growth rate (CAGR) of 3.3%. Factors contributing to growth in the past include the rising occurrence of mental health conditions, increasing awareness and diminished discrimination, improvements in diagnostic procedures, an increase in treatment choices, government schemes, and mental health regulations.

What's the Projected Size of the Global Antidepressants Market by 2029?
In the upcoming years, the steady expansion of the antidepressants market is projected, with it reaching "$19.92 billion by 2029 at a compound annual growth rate (CAGR) of 2.7%. This growth in the forecast period is due to various factors such as increased awareness about mental health, the global effect of stress and lifestyle changes, the merger of mental health services, advancements in psychiatric research, as well as telemedicine and remote mental health services. Key trends to look for during the forecast period includes regulatory shifts, market rivalry, the growth of the generic market, emphasis on side effect profiles, and the rise of emerging markets.

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Top Growth Drivers in the Antidepressants Industry: What's Accelerating the Market?
The surging occurrences of mental health-related issues across the globe have become a significant contributor to the burgeoning antidepressant drug industry. This is attributed to a large populace depending on these drugs to manage depression, anxiety disorders and various other mental illnesses. Antidepressant medicines find their application in the treatment of mental conditions, such as depression, OCD, childhood bed-wetting, major depression, extreme anxiety disorder, bipolar disorder, PTSD, and social anxiety disorder. The worldwide depression prevalence rate oscillates between 2% and 6%, with senior citizens displaying a higher susceptibility to depression compared to other demographics. As per WHO, an approximate figure of 280 million individuals worldwide were plagued by depression in 2023. Consequently, the escalating instances of mental health disorders are projected to fuel the expansion of the antidepressant market.

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What Long-Term Trends Will Define the Future of the Antidepressants Market?
A significant trend in the antidepressant market is the exploration of treatments for resistant depression. One of these new treatments is the use of Ketamine, which is traditionally utilised as anaesthesia during surgical procedures. The strength of Ketamine lies in its ability to induce glutamate production and stimulate the brain to establish fresh neural connections. Consequently, this leads to the brain becoming more flexible and capable of creating new pathways, boosting optimism in thoughts and actions. For instance, the Food and Drug Administration (FDA) gave approval to a new antidepressant that incorporates ketamine, named esketamine, which is a derivative of the ketamine compound. However, it should be noted that this drug needs to be administered via a nasal spray, while the patient is also on another antidepressant. Furthermore, this medication is only available to patients that have tried, and found unsatisfactory, at least two previous antidepressants.

What Are the Main Segments in the Antidepressants Market?
The antidepressants market covered in this report is segmented -

1) By Product: Selective Serotonin Reuptake Inhibitor (SSRI), Serotonin-norepinephrine Reuptake Inhibitor (SNRI), Tricyclic Antidepressant (TCA), Monoamine Oxidase Inhibitor (MAOI)
2) By Drug Class: Monoamine Oxidase Inhibitors, Serotonin Antagonist And Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, Selective Serotonin Reuptake Inhibitors, Tricyclic Antidepressants
3) By Depressive Disorder: Major Depressive Disorder, Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Panic Disorder

Subsegments:
1) By Selective Serotonin Reuptake Inhibitor (SSRI): Fluoxetine, Sertraline, Escitalopram, Paroxetine, Citalopram
2) By Serotonin-norepinephrine Reuptake Inhibitor (SNRI): Venlafaxine, Duloxetine, Desvenlafaxine
3) By Tricyclic Antidepressant (TCA): Amitriptyline, Nortriptyline, Imipramine, Doxepin
4) By Monoamine Oxidase Inhibitor (MAOI): Phenelzine, Tranylcypromine, Isocarboxazid

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Which Top Companies are Driving Growth in the Antidepressants Market?
Major companies operating in the antidepressants market include Pfizer Inc., Johnson & Johnson Services Inc., F. Hoffmann-La Roche Ltd., Merck & Co. Inc., AbbVie Inc., Novartis AG, Sanofi S.A., Bristol Myers Squibb Company, Fresenius Kabi AG, Abbott Laboratories, AstraZeneca plc, GlaxoSmithKline plc, Takeda Pharmaceutical Co. Ltd., Eli Lilly and Company, Boehringer Ingelheim GmbH, H. Lundbeck AS, Teva Pharmaceutical Industries Ltd., Akeda Pharmaceutical Co., Otsuka Pharmaceutical Co., Mylan N.V, Sun Pharmaceuticals Pvt. Ltd., Servier Laboratories, Sumitomo Dainippon Pharma Co., Aurobindo Pharma Limited, Dr. Reddy's Laboratories Ltd., Hikma Pharmaceuticals plc, Allergan plc, Alkermes plc, Egis Pharmaceuticals plc, Forest Laboratories Inc.

Which Regions Will Dominate the Antidepressants Market Through 2029?
North America was the largest region in the antidepressants market in 2024. Middle East is expected to be the largest growing region in the global antidepressants market during the forecast period. The regions covered in the antidepressants market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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