North America hepatitis B treatment market Size to Reach US$ 3.01 billion by 2033 - Exclusive Report by DataM Intelligence

The North America hepatitis B treatment market was valued at US$ 1.66 billion in 2024 and is projected to reach US$ 3.01 billion by 2033, growing at a CAGR of 6.9% during the forecast period 2025-2033.

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Market Drivers:
➠ Rising Prevalence of Hepatitis B
The growing number of chronic hepatitis B cases in North America fuels demand for effective treatments. Increased diagnosis rates through routine screening have contributed to a higher number of patients receiving antiviral therapies and other interventions.

➠ Advancements in Treatment Options
The introduction of novel antiviral drugs and combination therapies with improved efficacy and reduced side effects has strengthened the treatment landscape. Continuous research and clinical trials are expanding therapeutic choices for patients, encouraging higher adoption rates.

➠ Government and Public Health Initiatives
Government programs aimed at raising awareness, vaccination drives, and subsidized treatment plans are playing a crucial role in supporting the market. Policies promoting early diagnosis and treatment adherence are also boosting market growth.

➠ Increasing Healthcare Expenditure
Rising investments in healthcare infrastructure, particularly in diagnostics and specialized treatment facilities, facilitate access to hepatitis B therapies. Improved healthcare insurance coverage further enhances patient access to treatments.

➠ Patient Awareness and Education
Educational campaigns highlighting the risks of hepatitis B and benefits of early treatment are motivating more individuals to seek medical care. Growing awareness about lifestyle management and vaccination contributes to better disease control and market growth.

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Market Segments:
By Type (Chronic, Acute)
By Treatment (Vaccines, Antiviral Drugs, Immuno Modulator Drugs)
By Route of Administration (Parenteral, Oral)
By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies, Others)

Clinical Advancements & Product Launches 2025:

✅ Gilead Sciences acquired sole ownership of HB-400, an arenavirus-based therapeutic vaccine for chronic hepatitis B, from Hookipa Pharma. This $10 million deal strengthens Gilead's commitment to HBV vaccine development.

✅ Precision BioSciences received clearance for PBGENE-HBV, an in vivo gene-editing therapy targeting chronic hepatitis B. This marks the first investigational gene-editing therapy cleared for clinical trials in this indication.

✅ Tune Therapeutics, a Seattle-based biotech company, is developing Tune-401, an epigenetic gene therapy aimed at curing hepatitis B by halting the virus's replication. Clinical trials are expected to commence by the end of the year.

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✅ Assembly Biosciences initiated a Phase 1b clinical trial for ABI-4334, a next-generation capsid assembly modulator designed to treat chronic hepatitis B. The trial aims to evaluate the safety, tolerability, pharmacokinetics, and antiviral activity of ABI-4334.

✅ GSK acquired efimosfermin from Boston Pharmaceuticals for up to $2 billion. This acquisition enhances GSK's hepatology portfolio, targeting both viral liver diseases like chronic hepatitis B and metabolic conditions such as non-alcoholic steatohepatitis (NASH).

Key Market Players:
Key players are Gilead Sciences, Dynavax Technologies Corporation, GSK Plc, Merck & Co. Inc., Sanofi, Apotex Inc., VBI Vaccines Inc., Bristol-Myers Squibb Company, and Viatris Inc.

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