Personalized Cancer Vaccines Market Growth Accelerates at 11.5% CAGR, Fueled by Rising Cancer Burden, Targeted Therapies, and Innovation in USA and Japan

"The global personalized cancer vaccines market size reached US$ 11.33 Billion in 2024 from US$ 10.21 Billion in 2023 and is expected to reach US$ 30.12 Billion by 2033, growing at a CAGR of 11.5% during the forecast period 2025-2033." As per DataM intelligence research report

The Personalized Cancer Vaccines Market report by DataM Intelligence provides comprehensive insights and analysis on key market trends, growth opportunities, and emerging challenges. With a commitment to delivering actionable intelligence, DataM Intelligence empowers businesses to make informed decisions and stay ahead of the competition. By combining qualitative and quantitative research methodologies, the firm delivers in-depth reports that help clients navigate complex market dynamics, drive strategic growth, and seize new opportunities in an ever-evolving global landscape.

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Personalized Cancer Vaccines Market: Recent Industry Developments

USA

• NeoVax personalized vaccine formulation and delivery showed improved immune responses in a recent phase-1 trial update (July 2025).

• ELI-002 (KRAS-targeted) final AMPLIFY-201 data showed strong T-cell responses and correlation with longer relapse-free and overall survival in early-stage pancreatic and colorectal cancers (Aug 2025).

• Multiple US academic trials, including PGV001 at Mount Sinai, continue to report feasibility and promising immune activity for personalized cancer vaccines.

• Funding in the US biotech sector remained active in mid-2025, with large rounds supporting mRNA and therapeutic vaccine platforms.

Japan

• NEC and Transgene reported sustained T-cell responses and favorable 24-month disease-free outcomes for TG4050, with Phase I/II program advancing and new patient screenings completed (June 2025).

• NEC is using AI/ML neoantigen prediction to accelerate personalized vaccine design, highlighting Japan's strength in digital integration into biopharma.

• Domestic cancer vaccine market projections for mid-2025 show steady growth, with rising adoption of RNA/DNA and vector-based approaches.

• Technological focus remains on combining AI prediction with vector, peptide, and mRNA platforms, enhancing personalization speed and precision.

Personalized Cancer Vaccines Market: Drivers

The personalized cancer vaccines market is driven by the growing cancer burden and the need for targeted, less invasive treatments. Advances in mRNA and immunotherapy are enabling faster, tumor-specific vaccine development. Strong investments, government support, and pharma-biotech collaborations are accelerating clinical progress. These factors are positioning personalized vaccines as a key future therapy.

Adoption of neoantigen-based vaccines is boosting precision and minimizing side effects. AI tools and predictive models are improving vaccine design and scalability. mRNA platforms are streamlining production, making personalized treatments more accessible. Rising cancer cases in emerging economies and healthcare investments further fuel global market growth.

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Segment Covered in the Personalized Cancer Vaccines Market:

➥ By Vaccine Type: Dendritic Cell Vaccines, mRNA-based Vaccines, DNA-based Vaccines, Peptide-based Vaccines, Viral Vector Vaccines, Protein-based Vaccines, Others

➥ By Indication: Melanoma, Lung Cancer, Pancreatic Cancer, Breast Cancer, Colorectal Cancer, Glioblastoma, Prostate Cancer, Cervical Cancer, Others

➥ By End-User: Hospitals, Cancer Research Centers, Biotechnology & Pharma Companies, Academic Institutions, Others

Personalized Cancer Vaccines Market: Major Players

• BioNTech SE,

• Merck & Co., Inc.,

• Moderna, Inc.,

• Gritstone Bio,

• Transgene,

• CureVac SE,

• Nouscom,

Evaxion A/S.

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➡ A descriptive analysis of demand-supply gap, market size estimation, SWOT analysis, PESTEL Analysis and forecast in the global market.
➡ Top-down and bottom-up approach for regional analysis
➡ Porter's five forces model gives an in-depth analysis of buyers and suppliers, threats of new entrants & substitutes and competition amongst the key market players.
➡ By understanding the value chain analysis, the stakeholders can get a clear and detailed picture of this Market

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Regional Analysis:

⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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✅ Consumer Behavior & Demand Analysis
✅ Import-Export Data Monitoring
✅ Live Market & Pricing Trends

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