Press release
Adeno-Associated Virus Vectors Manufacturing Market to Reach USD 2.79 Billion by 2030, Fueled by Cell-Line Shifts and Asia-Pacific Expansion
Adeno-Associated Virus Vectors Manufacturing Market Size & Trends | Mordor Intelligence
The Adeno-Associated Virus (AAV) Vectors Manufacturing Market is set to grow from USD 1.82 billion in 2025 to USD 2.79 billion by 2030, representing a solid CAGR of 8.9% as forecasted by Mordor Intelligence. This growth is propelled by expanding clinical adoption of in vivo gene therapies and bolstered regulatory support. Notably, the FDA has set an ambitious goal of approving 10-20 gene therapies annually, which is encouraging investment in manufacturing capacity.
In addition, strategic moves by key players-such as Lonza's acquisition of Roche's Vacaville facility and Thermo Fisher's optimization of its vector manufacturing footprint-are reshaping capacity and supply dynamics within the industry.
Report Overview: https://www.mordorintelligence.com/industry-reports/adeno-associated-virus-vectors-manufacturing-market?utm_source=openpr
Key Trends
Cell-line innovation reshaping manufacturing workflows
Producer cell lines are gaining popularity over traditional HEK293 systems. They simplify workflows by eliminating multi-plasmid transfection steps, improving consistency and enabling more streamlined production operations.
Purification techniques are evolving toward cost-efficiency
While affinity chromatography remains the default choice for its selectivity and yield, alternatives like ion-exchange chromatography are gaining traction. These options offer lower cost and greater scalability, easing pressure on supply and cost of goods.
Therapeutic focus shifting beyond the eye
Ophthalmology continues to lead AAV vector use due to favorable anatomical and immunological traits. However, neurology is rapidly gaining ground thanks to new capsids engineered for blood-brain barrier penetration-opening up treatment options for CNS disorders.
CDMOs expanding share amid outsourcing surge
Contract Development and Manufacturing Organizations (CDMOs) are capturing growth as pharma and biotech companies increasingly outsource vector production. Their rising share reflects the industry prioritizing efficiency and scalability.
Asia-Pacific emerges as the growth engine
Asia-Pacific is poised to be the fastest-growing region. Governments in markets like China, South Korea, and India are heavily investing in biomanufacturing capacity, while CDMO ecosystems are being actively developed to capture global demand.
Check out more details and stay updated with the latest industry trends, including the Japanese version for localized insights: https://www.mordorintelligence.com/ja/industry-reports/adeno-associated-virus-vectors-manufacturing-market?utm_source=openpr
Market Segmentation
By Vector Type
Single-stranded AAV Vectors
Self-complementary AAV Vectors
By Production Platform
HEK293 Cell Platform
Sf9/Baculovirus System
Producer Cell Line (PCL)
Other Systems
By Purification Method
Affinity Chromatography
Ion Exchange Chromatography
Ultrafiltration / Diafiltration
CsCl Gradient Centrifugation
By Therapeutic Area
Ophthalmology
Neurology
Hematology
Musculoskeletal
Metabolic Disorders
Oncology
Other Therapeutic Areas
By End-User
Pharma & Biotech Companies
CDMOs / CMOs
Academic & Research Institutes
By Region:
North America
Europe
Asia‐Pacific
South America
Middle East & Africa
Explore Our Full Library of Healthcare Industry Research Reports
https://www.mordorintelligence.com/market-analysis/healthcare?utm_source=openpr
Key Players
The AAV manufacturing market shows a medium level of concentration. Major players include:
Creative Biogene
F. Hoffmann-La Roche Ltd
GenScript
Lonza
WuXi AppTec
These organizations continue to scale through acquisitions, tech integration, and infrastructure investments, reinforcing their dominance in the vector manufacturing landscape.
Conclusion
The AAV Vectors Manufacturing Market is on track to growth from approximately USD 1.82 billion in 2025 to USD 2.79 billion by 2030, at a CAGR of 8.9%, driven by increasing gene therapy adoption and strategic capacity expansions.
The market is pivoting toward more efficient platforms and cost-effective techniques: self-complementary vectors and producer-cell lines offer performance and operational efficiency gains. Purification is shifting toward scalable, cost-sensitive methods, and therapeutic expansion beyond ophthalmology-especially into neurology-is opening new revenue streams.
CDMOs are securing a growing proportion of manufacturing through specialized service offerings, while Asia-Pacific becomes the main growth hub for infrastructure development. North America remains dominant, but Asia-Pacific's trajectory signals a shift in global production dynamics.
For complete market analysis, visit the Mordor Intelligence page: https://www.mordorintelligence.com/industry-reports/adeno-associated-virus-vectors-manufacturing-market?utm_source=openpr
Industry Related Reports
Adeno-Associated Virus (AAV) CDMO Market: The AAV CDMO market report segments the industry into By Workflow (Upstream Processing, Downstream Processing), By Culture Type (Adherent Culture, Suspension Culture), By Application (Cell & Gene Therapy Development, Vaccine Development, Biopharmaceutical & Pharmaceutical Discovery, and more), By End User (Pharmaceutical & Biopharmaceutical Companies, Academic & Research Institutes), and Geography.
Get more insights: https://www.mordorintelligence.com/industry-reports/adeno-associated-virus-aav-cdmo-market?utm_source=openpr
Gene Vector Market: The Gene Vector Market Report is Segmented by Vector Type (Viral Vectors Including AAV, Lentivirus, and More), Delivery Method (In-Vivo and Ex-Vivo), Therapy Area (Oncology, Genetic Disorders, and More), End User (Biopharma Companies, and More), Production Workflow (Upstream and Downstream), and Geography (North America, Europe, Asia-Pacific, MEA, South America).
Get more insights: https://www.mordorintelligence.com/industry-reports/gene-vector-market?utm_source=openpr
Viral Vector Contract Development and Manufacturing Organization (CDMO) Market: The Viral Vector CDMO Market report segments the industry into By Vector Type (Adenovirus, Retrovirus, Adeno-Associated Virus, Lentivirus, Others), By Workflow (Upstream Manufacturing, Downstream Manufacturing), By Application (Antisense & RNAi Therapy, Gene Therapy, Cell Therapy, Vaccinology, Other Applications), By End User (Pharmaceutical & Biopharmaceutical Companies, Academic and Research Institutes), and Geography.
Get more insights: https://www.mordorintelligence.com/industry-reports/viral-vector-contract-development-and-manufacturing-organization-cdmo-market?utm_source=openpr
About Mordor Intelligence:
Mordor Intelligence is a trusted partner for businesses seeking comprehensive and actionable market intelligence. Our global reach, expert team, and tailored solutions empower organizations and individuals to make informed decisions, navigate complex markets, and achieve their strategic goals.
With a team of over 550 domain experts and on-ground specialists spanning 150+ countries, Mordor Intelligence possesses a unique understanding of the global business landscape. This expertise translates into comprehensive syndicated and custom research reports covering a wide spectrum of industries, including aerospace & defense, agriculture, animal nutrition and wellness, automation, automotive, chemicals & materials, consumer goods & services, electronics, energy & power, financial services, food & beverages, healthcare, hospitality & tourism, information & communications technology, investment opportunities, and logistics.
For any inquiries or to access the full report, please contact:
media@mordorintelligence.com
https://www.mordorintelligence.com/
Mordor Intelligence, 11th Floor, Rajapushpa Summit, Nanakramguda Rd, Financial District, Gachibowli, Hyderabad, Telangana - 500032, India
Mordor Intelligence is a trusted partner for businesses seeking comprehensive and actionable market intelligence. Our global reach, expert team, and tailored solutions empower organizations and individuals to make informed decisions, navigate complex markets, and achieve their strategic goals.
With a team of over 550 domain experts and on-ground specialists spanning 150+ countries, Mordor Intelligence possesses a unique understanding of the global business landscape. This expertise translates into comprehensive syndicated and custom research reports covering a wide spectrum of industries, including aerospace & defense, agriculture, animal nutrition and wellness, automation, automotive, chemicals & materials, consumer goods & services, electronics, energy & power, financial services, food & beverages, healthcare, hospitality & tourism, information & communications technology, investment opportunities, and logistics.
For any inquiries or to access the full report, please contact:
media@mordorintelligence.com
https://www.mordorintelligence.com/
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