Press release
Global Biologics Drug Discovery Market to Surpass USD 1 Trillion by 2033, Fueled by AI Innovation and Personalized Therapies
Biologics Drug Discovery Market
Biologics-such as monoclonal antibodies, gene therapies, and cell-based treatments-have emerged as powerful tools in combating chronic and complex diseases, including cancer, autoimmune disorders, and genetic conditions. These treatments offer a more targeted and personalized approach, which often leads to better outcomes and fewer side effects than conventional drugs.
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AI Driving Breakthroughs in Drug Discovery
AI is playing a transformative role in accelerating the biologics discovery process. AI-powered platforms are now being used to identify effective antibody candidates, predict immune responses, and streamline pre-clinical testing. This significantly reduces the time and cost associated with drug development.
For example, Sanofi's partnership with Atomwise in 2022 highlights this shift, with a potential deal worth up to USD 1.2 billion aimed at developing AI-based drug candidates.
In another milestone, Variational AI, a Canadian company, secured USD 5.5 million in February 2025 to expand its AI-based drug discovery tools, signaling strong investor interest in this space.
Precision Medicine and Genomics Driving Demand
The increasing emphasis on precision medicine and the growth of genomic research are also fueling demand for biologics. As more is understood about the genetic and molecular basis of disease, new biologic therapies are being developed that specifically target these mechanisms-leading to more personalized and effective treatments.
Technological Innovations Enhance Efficiency
In addition to AI, tools like CRISPR gene editing, high-throughput screening, and next-generation sequencing are making it easier to discover and refine biologic drug candidates. These technologies help identify promising drug targets faster and with greater accuracy, ultimately speeding up the path from research to market.
Cold Chain Challenges Remain a Concern
Despite the promising outlook, the biologics market faces significant logistical challenges-particularly in maintaining proper storage conditions. Biologic drugs are highly sensitive and require strict cold chain management throughout production and distribution. Any temperature fluctuation can compromise drug quality, adding to costs and complexity.
Outsourced Manufacturing Leads, In-House Gains Momentum
In terms of manufacturing, outsourced production currently dominates due to its cost efficiency and access to specialized expertise. Many biotech companies partner with contract development and manufacturing organizations (CDMOs) to avoid the high cost of building in-house facilities.
However, in-house manufacturing is growing rapidly, driven by the need for tighter quality control, faster turnaround times, and improved intellectual property protection. The COVID-19 pandemic underscored the importance of internal manufacturing capabilities, pushing many firms to invest in their own infrastructure. New technologies like automated and continuous manufacturing are making this shift more feasible.
Biologics Drug Discovery Market Top Companies and Competitive Landscape
The competitive landscape of the biologics drug discovery market is characterized by the presence of large pharmaceutical companies, biotech firms, contract development and manufacturing organizations (CDMOs), and specialized technology providers. Biologics Drug Discovery Market Leaders
Amgen
Merck & Co.
Hoffmann-La Roche Ltd.
Bristol-Myers Squibb
Sanofi
Bayer AG
AstraZeneca
GlaxoSmithKline Plc.
Novartis AG
Eli Lilly and Company
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Biologics Drug Discovery Market Latest Industry Updates
In June 2022, Janssen Pharmaceutical Companies of Johnson & Johnson received the United States Food and Drug Administration (FDA) approval for CARVYKTI (ciltacabtagene autoleucel; cilia-cel). This biologic medicine treats adults with relapsed or refractory multiple myeloma (RRMM) after four or more prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
In September 2022, Verge Genomics, a clinical-stage and technology-enabled biotechnology company pioneering the use of artificial intelligence (AI) and human data to transform drug discovery, announced dosing the first subject in its Phase 1 clinical trial of VRG50635.
Biologics Drug Discovery Market Market Segmentation Analysis
Type Outlook (Revenue, USD Billion, 2021-2034)
Blood and Blood Products
Cellular and Gene Therapy Products
Tissue and Tissue Products
Vaccines
Others Types
Indication Outlook (Revenue, USD Billion, 2021-2034)
Oncology
Immunology
Infectiuos Disease
Other Indications
Application Outlook (Revenue, USD Billion, 2021-2034)
Diagnosis
Treatment
Manufacturing Facility Outlook (Revenue, USD Billion, 2021-2034)
Outsourced
In-house
Regional Outlook (Revenue, USD Billion, 2021-2034)
North America
United States
Canada
Mexico
Europe
Germany
France
United Kingdom
Italy
Spain
Benelux
Rest of Europe
Asia-Pacific
China
India
Japan
South Korea
Rest of Asia-Pacific
Latin America
Brazil
Rest of Latin America
Middle East and Africa
Saudi Arabia
UAE
South Africa
Turkey
Rest of MEA
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