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Ulcerative Colitis Therapeutics Market to Reach USD 11.9 Billion by 2035, Growing at a CAGR of 5.1% Amid Rising Prevalence and Advancements in Treatment Options

07-25-2025 04:56 PM CET | Business, Economy, Finances, Banking & Insurance

Press release from: FactMR

Ulcerative Colitis Therapeutics Market to Reach USD 11.9

The global ulcerative colitis therapeutics market is valued at USD 7.2 billion in 2025. As per Fact.MR analysis, the industry will grow at a CAGR of 5.1% and will reach USD 11.9 billion by 2035. according to Fact.MR's comprehensive analysis. The increasing prevalence of ulcerative colitis, a chronic inflammatory bowel disease causing inflammation and ulceration in the large bowel , is a primary driver of market growth. Rising awareness of the condition, advancements in diagnostic technologies, and the growing adoption of biologics and targeted therapies are further fueling the market's expansion. The focus on personalized medicine and the integration of artificial intelligence (AI) in drug development and disease management are also enhancing treatment efficacy, positioning the market for steady growth over the forecast period.

The demand for ulcerative colitis therapeutics is driven by the increasing incidence of inflammatory bowel diseases globally, coupled with innovations in biologics, such as JAK inhibitors and monoclonal antibodies. These therapies offer improved outcomes for patients with moderate to severe ulcerative colitis, contributing to market growth. Additionally, enhanced diagnostic capabilities and rising patient education are encouraging early diagnosis and treatment, further boosting demand. The market is also benefiting from strategic partnerships, mergers, and acquisitions, which are expanding access to innovative treatments and strengthening global distribution networks.

Ulcerative colitis therapeutics are used across various disease types, including ulcerative proctitis, proctosigmoiditis, left-sided colitis, pancolitis, and fulminant colitis. Pancolitis, or universal colitis, is the most profitable segment due to its severity and reliance on costly biologics and immunosuppressants, with an estimated CAGR of 5.5% through 2035. By route of administration, injectables, particularly biologics and monoclonal antibodies, are experiencing faster uptake due to their higher efficacy and longer remission periods, with a projected CAGR of 5.6%. Oral treatments, such as aminosalicylates and corticosteroids, remain widely used for mild to moderate cases due to their ease of use and patient preference.

Browse Full Report: https://www.factmr.com/report/ulcerative-colitis-therapeutics-market

"Innovation in biologics and precision medicine is transforming ulcerative colitis treatment, improving patient outcomes and driving market growth. Companies must prioritize R&D investments and strategic partnerships to stay competitive in this rapidly evolving landscape," opines a Fact.MR analyst.

Ulcerative Colitis Therapeutics Market Insights: Key Trends and Growth

The Fact.MR report underscores robust market growth driven by the rising prevalence of ulcerative colitis, advancements in therapeutic options, and increasing adoption of biosimilars. Key trends include the growing use of JAK inhibitors and monoclonal antibodies for aggressive disease management and the integration of AI-powered diagnostics for personalized treatment. North America and Europe dominate the market due to advanced healthcare infrastructure and high disease prevalence, while the Asia-Pacific region, particularly India and China, is witnessing rapid growth due to improving healthcare systems and rising awareness. However, challenges such as regulatory barriers, competition from biosimilars, and supply chain disruptions pose risks to market expansion.

Key Takeaways from the Market Study

-The global ulcerative colitis therapeutics market is expected to grow at a CAGR of 5.1% from 2025 to 2035, reaching USD 11.9 billion.
-North America leads the market, with the United States projected to grow at a CAGR of 5.3% through 2035, driven by high R&D expenditure and biologics uptake.
-The Asia-Pacific region, led by India (CAGR 5.6%) and China (CAGR 5.4%), is emerging as a high-growth market due to increasing healthcare investments.
-Pancolitis is the most lucrative disease type segment, with a CAGR of 5.5%, driven by demand for advanced biologics.
-Injectables are the fastest-growing route of administration, with a CAGR of 5.6%, due to their efficacy in severe cases.
-Biosimilars are gaining traction, particularly in Europe (84% stakeholder focus), to address affordability concerns.

Ulcerative Colitis Therapeutics Market Competitive Landscape

The ulcerative colitis therapeutics market is moderately consolidated, with key players like AbbVie, Johnson & Johnson (Janssen), Takeda Pharmaceutical, Pfizer, and Bristol-Myers Squibb dominating through innovation and strategic collaborations. AbbVie holds the largest market share (35-40%) with drugs like Humira, Rinvoq, and Skyrizi, followed by Janssen (20-25%) with Stelara and Takeda (15-20%) with Entyvio. Recent developments include AbbVie's acquisition of Landos Biopharma in March 2024 for USD 137 million to bolster its inflammatory bowel disease portfolio and Teva Pharmaceuticals' promising Phase 2b trial results for duvakitug in December 2024. The European Medicines Agency's endorsement of ustekinumab biosimilars, such as Yesintek, in December 2024 further intensifies competition. Companies are focusing on next-generation biologics, AI-driven diagnostics, and global expansion to maintain market leadership.

Ulcerative Colitis Therapeutics Market Key Companies Profiled

AbbVie
Takeda Pharmaceutical
Pfizer
Bristol-Myers Squibb
Roche/Genentech
Amgen
AstraZeneca
Eli Lilly
Merck & Co.
Gilead Sciences
Cosmo Pharmaceuticals
Astellas Pharma
BioLineRx
Landos Biopharma
Celltrion

For More Insights into the Market, Request a Sample of this Report: https://www.factmr.com/connectus/sample?flag=S&rep_id=7286

Ulcerative Colitis Therapeutics Industry News

-In March 2024, AbbVie acquired Landos Biopharma to expand its ulcerative colitis portfolio with NX-13, an oral drug candidate.
-In December 2024, Teva Pharmaceuticals and Sanofi reported positive Phase 2b trial results for duvakitug, advancing to Phase 3 trials.
-In December 2024, the European Medicines Agency endorsed ustekinumab biosimilars for ulcerative colitis treatment, enhancing affordability.

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Fact.MR is a trusted market research partner for 80% of Fortune 1000 companies globally, delivering over 1000 reports annually. With a dedicated team of 400+ analysts and consultants, Fact.MR provides actionable insights to drive client satisfaction.

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