Press release
Peptide-Drug Conjugates Market to Grow Significantly Amid Increased Investments and Promising Pipeline Developments
Peptide-Drug Conjugates Market
According to the latest research by InsightAce Analytic, the global peptide-drug conjugates (PDCs) market is expected to record a promising CAGR of 18.8% during the period of 2025-2034. By region, North America dominates the global peptide-drug conjugates (PDCs) market with the largest share.
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Peptide-drug conjugates (PDCs) represent an emerging class of targeted therapeutics engineered to selectively deliver cytotoxic agents to tumor cells. Increasing investments by leading industry participants in the development of innovative PDC-based therapies are expected to significantly drive market growth over the forecast period. The expanding clinical relevance of PDCs as viable treatment options for various cancer types is anticipated to present substantial opportunities within the oncology landscape.
PDCs are composed of short peptide chains-typically comprising around ten amino acids-which enable precise targeting of malignant cells. Due to their relatively low molecular weight compared to antibody-drug conjugates (ADCs), PDCs can accumulate more rapidly at tumor sites. Furthermore, their shorter systemic half-life reduces the likelihood of off-target toxicity, thereby improving the safety profile of these therapies.
As a novel form of targeted treatment, PDCs offer improved tumor penetration and selectivity. The field is witnessing active research and development, with two PDC-based therapies already available in the commercial market. With optimized design and application, PDCs are poised to make a meaningful contribution to the targeted therapeutics sector by providing safer and more efficacious treatment alternatives.
The advancement of pharmaceutical innovation, particularly in oncology drug development, is expected to further support the growth of the PDC market. Additionally, a strong clinical pipeline and the potential for accelerated regulatory approvals are likely to facilitate the introduction of new cancer therapies, thereby contributing to the market's expansion in the foreseeable future.
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Despite the promising outlook, several challenges continue to restrain the growth of the peptide-drug conjugates (PDCs) market. High treatment costs, the complexity of development and administration procedures, and the absence of comprehensive regulatory frameworks pose notable barriers to market advancement. Additionally, the COVID-19 pandemic adversely affected the sector by causing widespread disruptions to clinical trials and delaying research activities due to global lockdowns.
The slow regulatory approval process and the limited number of PDC-specific approvals granted by the U.S. Food and Drug Administration (FDA) in recent years further constrain market expansion during the forecast period.
From a regional perspective, North America-followed closely by Europe-is anticipated to lead the global PDCs market. This dominance is attributed to a high incidence of cancer, accelerated adoption of cutting-edge technologies, heightened awareness regarding novel therapeutic solutions, and substantial government funding in research and development. Meanwhile, the Asia-Pacific region is projected to witness robust growth, propelled by technological advancements and an increasing cancer burden across key markets such as China, India, and Japan.
The key players involved in peptide-drug conjugates (PDCs) industry are Novartis AG, AstraZeneca, Bicycle Therapeutics, Cybrexa Therapeutics, Esperance Pharmaceuticals, Oncopeptides AB, Pepgen Corporation, Soricimed Biopharma, Theratechnologies, Pfizer Inc, Validus Pharmaceuticals LLC, Antisense Therapeutics, Midatech Pharma PLC, Ipsen Pharma, Chiasma, Inc., Peptron, Inc., CRINETICS PHARMACEUTICALS, Dauntless Pharmaceuticals, Camurus AB, Teva Pharmaceuticals Inc., Pharmaspur, Aspire Pharmaceuticals, Ionis Pharmaceuticals Inc, Midatech Pharma Plc, and Other Prominent Players. This field's leading players use strategies like novel therapy innovations, partnerships, collaborations, mergers, and agreements.
Key developments in the market
• In Dec 2021, A strategic partnership agreement was signed between Coherent Biopharma and WuXi STA. In order to speed up the development of its current and future drug candidates (small molecules, peptides, oligonucleotides, complex chemical conjugates, etc.), from API to drug product, the company will offer Coherent Biopharma integrated CMC services.
• In Oct 2021, Oncopeptides AB announced the withdrawal of Pepaxto® (INN melphalan flufenamide) from the US market. Oncopeptides will collaborate with the FDA to keep the drug available for patients who are currently receiving Pepaxto treatment.
• In July 2020, AstraZeneca and Daiichi Sankyo formed a new $6 billion global ADC alliance to co-develop and commercialise DS-1062, a TROP2 directed DXd antibody-drug conjugate in Phase I for non-small cell lung cancer and breast cancer. The businesses will share development and commercialization costs as well as profits from DS-1062 worldwide, except for Japan.
• In June 2019, Novartis AG and PeptiDream Inc. signed a new Peptide Drug Conjugate "PDC" collaboration agreement to initiate macrocyclic peptide discovery, which will be used to address therapeutic and diagnostic applications.
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Market Segments
Global peptide-drug Conjugates (PDCs) Market, by Product, 2022-2030 (Value US$ Mn)
• Lutetium Lu 177 dotatate
• Melflufen
• ANG1005
• BT1718
• CBX-12
• Other Pipeline Products
Global peptide-drug Conjugates (PDCs) Market, by Indication, 2022-2030 (Value US$ Mn)
• Relapsed/Refractory Multiple Myeloma
• Neuroendocrine Tumors (NETs)
• Gastric Cancers
• Acromegaly
• Ophthalmology
• Other Cancer Indication
Global peptide-drug Conjugates (PDCs) Market, by Region, 2022-2030 (Value US$ Mn)
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa
North America Peptide-drug Conjugates (PDCs) Market, by Country, 2022-2030 (Value US$ Mn)
• U.S.
• Canada
Europe Peptide-drug Conjugates (PDCs) Market, by Country, 2022-2030 (Value US$ Mn)
• Germany
• France
• Italy
• Spain
• Russia
• Rest of Europe
Asia Pacific Peptide-drug Conjugates (PDCs) Market, by Country, 2022-2030 (Value US$ Mn)
• India
• China
• Japan
• South Korea
• Australia & New Zealand
Latin America Peptide-drug Conjugates (PDCs) Market, by Country, 2022-2030 (Value US$ Mn)
• Brazil
• Mexico
• Rest of Latin America
Middle East & Africa Peptide-drug Conjugates (PDCs) Market, by Country, 2022-2030 (Value US$ Mn)
• GCC Countries
• South Africa
• Rest of Middle East & Africa
Read Overview Report- https://www.insightaceanalytic.com/report/global-peptidedrug-conjugates-pdcs-market/1351
Why should buy this report:
• To receive a comprehensive analysis of the prospects for global peptide-drug conjugates (PDCs) products
• To receive industry overview and future clinical trial/pipeline trends of global peptide-drug conjugates (PDCs) market
• To analyse the peptide-drug conjugates (PDCs) market drivers and challenges
• To get information on peptide-drug conjugates (PDCs) market size value (US$ Mn) forecast till 2030
• To get information on major Investments, Mergers & Acquisition in global peptide-drug conjugates (PDCs) market industry
About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.
Contact us:
InsightAce Analytic Pvt. Ltd.
Visit: www.insightaceanalytic.com
Tel : +1 607 400-7072
Asia: +91 79 72967118
info@insightaceanalytic.com
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