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mRNA Vaccines and Therapeutics Market to Reach USD 85.9 Billion by 2034 | Growing at a CAGR of 14.6% from 2024 to 2034 - Analysis by TMR

07-18-2025 06:40 AM CET | Health & Medicine

Press release from: Transparency Market Research

mRNA Vaccines and Therapeutics Market

mRNA Vaccines and Therapeutics Market

The global mRNA vaccines and therapeutics market has emerged as a critical pillar in the biomedical sector, especially in the wake of the COVID-19 pandemic, which demonstrated the immense potential of mRNA technology in rapidly developing life-saving vaccines. This transformative technology, which allows for the direct encoding of proteins into the human body to trigger immune responses or therapeutic action, is now being increasingly adopted in diverse medical fields beyond infectious diseases, including oncology, rare genetic disorders, and autoimmune diseases. The flexibility, scalability, and precision of mRNA platforms have captivated the pharmaceutical landscape, leading to exponential interest and investment from both public and private stakeholders.

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Market Size and Growth

In 2023, the global mRNA vaccines and therapeutics market was valued at US$ 19.6 billion. The industry is poised for robust expansion, with projections indicating a compound annual growth rate (CAGR) of 14.6% from 2024 through 2034. By the end of the forecast period, the market is expected to reach an impressive valuation of US$ 85.9 billion. This remarkable growth trajectory is being driven by the rising global prevalence of chronic and infectious diseases, increasing government and private funding for R&D, and expanding applications of mRNA in therapeutics beyond its initial role in combating SARS-CoV-2.

Market Segmentation

The mRNA vaccines and therapeutics market can be segmented based on application, end-user, route of administration, and region. By application, the market is categorized into infectious diseases, oncology, rare genetic disorders, and others. While infectious diseases remain the dominant segment, the oncology application is witnessing a sharp rise due to the development of personalized cancer vaccines and immunotherapy approaches. Based on end-users, hospitals, research institutes, biotechnology firms, and contract manufacturing organizations (CMOs) represent key participants in the value chain. The route of administration includes intramuscular, intravenous, and intradermal, with intramuscular delivery holding the lion's share due to its effectiveness in vaccine administration.

Regional Analysis

North America continues to dominate the global landscape, spearheaded by significant investments in biotechnology, a robust R&D infrastructure, and the presence of key players such as Moderna and Pfizer. Europe follows closely, with strong contributions from countries like Germany and the United Kingdom. Asia Pacific is rapidly emerging as a promising market, driven by government initiatives in countries like China and India to boost biotech innovation and healthcare access. Latin America and the Middle East & Africa represent emerging opportunities, although infrastructure and regulatory hurdles may delay market penetration in these regions.

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Market Drivers and Challenges

The unprecedented success of mRNA vaccines in combating COVID-19 has galvanized support for the platform across the biomedical spectrum. Key drivers include rapid development timelines, the adaptability of mRNA platforms for different diseases, increasing prevalence of target diseases, and growing public and private sector investments in mRNA research. However, the market is not without challenges. High production costs, stringent regulatory environments, concerns around storage and cold chain logistics, and long-term safety validation remain key barriers to widespread adoption. Furthermore, global disparities in healthcare infrastructure may hinder equal access to these cutting-edge therapies.

Market Trends

Among the most notable trends is the expansion of mRNA technology beyond infectious diseases. Companies are exploring oncology-focused mRNA therapeutics for cancers such as melanoma, lung cancer, and breast cancer. Additionally, advancements in lipid nanoparticle delivery systems and improvements in cold chain logistics are enabling broader distribution and efficacy. The market is also seeing increasing collaborations between biotech startups and pharmaceutical giants, fostering innovation through shared expertise and accelerated clinical trial pipelines. Additionally, the rise of AI and machine learning in mRNA design is streamlining development and optimizing outcomes.

Competitive Landscape

The mRNA vaccines and therapeutics market is characterized by the presence of leading biotechnology innovators and pharmaceutical powerhouses. Key players include Moderna, Inc., BioNTech SE, CureVac SE, Arcturus Therapeutics, Inc., Sanofi, GSK plc, Argos Therapeutics Inc., Ethris, Pfizer Inc., and AstraZeneca. These companies are actively investing in R&D, clinical trials, strategic partnerships, and mergers & acquisitions to strengthen their market positions. Moderna and BioNTech, in particular, have become synonymous with mRNA innovation, while others such as CureVac and Arcturus are making significant strides in improving mRNA stability and delivery technologies.

Future Outlook

Looking ahead to 2034, the mRNA vaccines and therapeutics market is expected to evolve into a multi-disciplinary innovation hub, with applications across oncology, rare diseases, cardiovascular disorders, and even regenerative medicine. As research matures, we anticipate greater regulatory clarity, more personalized treatment options, and an influx of next-generation mRNA therapies. The widespread adoption of digital and AI-driven drug discovery tools will further enhance the speed and accuracy of mRNA drug development. Public-private partnerships, government incentives, and global health initiatives will play a crucial role in ensuring the scalability and accessibility of these life-saving technologies.

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About Transparency Market Research

Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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