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Peptide API Market Forecast 2034: Expansion of Biopharmaceutical R&D and Demand for Targeted Therapies Propel Market Growth | Transparency Market Research, Inc

07-16-2025 04:59 PM CET | Health & Medicine

Press release from: Transparency Market Research

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Peptide API Market

Peptide API Market

The global Peptide Active Pharmaceutical Ingredients (API) market is poised for explosive growth, with its valuation expected to surge from US$ 9.2 Bn in 2023 to over US$ 94.2 Bn by 2034, expanding at a CAGR of 22.4% during the forecast period. This expansion is propelled by the increasing global burden of chronic diseases, particularly diabetes and obesity, coupled with the rising adoption of GLP-1 receptor agonists and insulin-based peptide therapies.

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Market Overview: Peptide APIs, comprised of short chains of amino acids, play a crucial role in modern medicine, particularly in managing metabolic, cardiovascular, and oncological disorders. These biologically active compounds function as hormones, enzymes, and signaling molecules. Peptide therapeutics such as insulin, liraglutide, and semaglutide have proven efficacy in improving glycemic control and promoting weight loss, fueling their demand in clinical practice.

With significant strides in peptide production techniques and the evolution of targeted drug delivery systems, the peptide API industry is gaining attention from pharmaceutical giants, biotech firms, and contract manufacturers across the globe.

Market Drivers & Trends

A primary market driver is the global rise in chronic disease prevalence, including cardiovascular diseases, type 2 diabetes, and obesity. According to global health statistics, approximately 523 million people suffered from some form of cardiovascular disease in 2020, and chronic conditions are projected to cost the world US$ 47 trillion by 2030.

Another significant growth lever is the advancement in peptide synthesis technologies, such as Solid Phase Peptide Synthesis (SPPS), Liquid Phase Peptide Synthesis (LPPS), and recombinant DNA techniques. These methods enable high-throughput, cost-effective, and scalable production of complex peptides, including long-chain variants.

Latest Market Trends

• GLP-1 receptor agonists are dominating the peptide API landscape owing to their dual role in type 2 diabetes and weight management.
• Once-weekly injection formulations and oral delivery options are gaining rapid acceptance, improving patient compliance.
• Pharmaceutical giants are heavily investing in expanding infrastructure for injectable treatments, as seen in Novo Nordisk's US$ 4.1 Bn investment in North Carolina.
• Microwave-assisted synthesis and automated synthesizers are further streamlining peptide production, enhancing reproducibility and yield.

Key Players and Industry Leaders

The market landscape is highly competitive, with major pharmaceutical and biotech firms driving innovation and market expansion. Key players include:
• Eli Lilly and Company
• Sanofi
• Novo Nordisk
• AstraZeneca
• GlaxoSmithKline
• PegBio Co. Ltd.
• Amgen Inc.
• Pfizer Inc.
• Innovent Biologics
• Sun Pharmaceuticals
• Boehringer Ingelheim
• Biocon
• Wockhardt Ltd.
These companies are actively investing in R&D and clinical trials to enhance product portfolios and expand global reach.

Recent Developments

• In August 2024, Eli Lilly reported positive Phase 3 trial results for tirzepatide, showing significant improvements in heart failure outcomes.
• In July 2024, Novo Nordisk announced a massive US$ 4.1 billion expansion to ramp up production of injectable peptide therapeutics.
• In May 2024, Amgen revealed clinical success with AMG 890, a GLP-1 receptor agonist targeting obesity, intensifying competition in the metabolic disorder space.

Market New Opportunities and Challenges

Opportunities:
• Expansion of oral peptide drug delivery systems
• Rising geriatric population across Asia Pacific
• Increasing focus on personalized peptide therapeutics
• Potential for peptide-based cancer therapies
Challenges:
• Peptides' instability in gastrointestinal tract limits oral bioavailability
• High production cost of complex peptide APIs
• Navigating regulatory complexities for therapeutic approval

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Future Outlook

Analysts anticipate robust market performance over the next decade. The synergy between technological innovation, clinical advancements, and growing chronic disease prevalence will ensure sustained growth. Moreover, regulatory bodies are accelerating approvals for peptide-based therapies, providing a favorable framework for new entrants and established players alike.

Market Segmentation

By Drug Class:
• GLP-1 Receptor Agonists
• Insulin
• Other Peptide Classes

By Product Type:
• GLP-1 Receptor Agonist Oral Formulations
• GLP-1 Receptor Agonist Injectables
• Insulin Injectables
• Other Peptides

By Route of Administration:
• Oral
• Parenteral

By Application:
• Type 2 Diabetes Mellitus
• Type 1 Diabetes
• Obesity
• Non-alcoholic Fatty Liver Disease (NAFLD)
• Others

Regional Insights

North America led the global market in 2023 due to its robust healthcare infrastructure, high R&D investments, and rising incidence of chronic illnesses. The U.S. remains at the forefront, backed by advanced manufacturing capabilities and strong clinical networks.
Europe is also witnessing steady growth, particularly in Germany, France, and the U.K., owing to favorable regulatory support and increased funding for biotech innovations.
Asia Pacific is projected to record the fastest CAGR during the forecast period. The rising geriatric population, increasing healthcare spending, and growing demand for GLP-1 and insulin therapies are fostering regional expansion, especially in China, India, and Japan.

Why Buy This Report?

• Gain a comprehensive understanding of the peptide API market dynamics
• Analyze emerging trends, market drivers, and opportunities
• Identify growth segments and investment hotspots
• Review detailed company profiles, financials, and recent developments
• Access in-depth regional and segment-wise analysis
• Leverage strategic insights for product development and market entry
• Stay updated on competitive benchmarking and regulatory shifts

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About Transparency Market Research

Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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Transparency Market Research Inc.
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