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Antibody Mediated Rejection Market Projects Growth from Early‐Stage Enzyme & Monoclonal Platform Pipelines

07-16-2025 02:58 PM CET | Health & Medicine

Press release from: DataM Intelligence 4Market Research LLP

Antibody-Mediated Rejection

Antibody-Mediated Rejection

"Global Antibody-Mediated Rejection (AMR) Market is expected to reach a CAGR of 6.3% during the forecast period 2024-2031," according to DataM Intelligence.

The Antibody Mediated Rejection (AMR) market is led by biotech leaders like CSL Behring, Hansa Biopharma, and Novartis, developing complement inhibitors, enzyme-based therapies, and IgG-cleaving platforms. Talaris Therapeutics, Amgen, Bristol-Myers Squibb, Eli Lilly, and Sanofi are advancing monoclonal antibodies and immunomodulators in transplant care. Teva and Biogen complement the field through biosimilars and therapeutic antibodies.

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Antibody Mediated Rejection Market M&A & Collaborative Deals

1. Biogen's acquisition of Human Immunology Biosciences (HI Bio) for US$1.8 billion in May 2024, securing felzartamab, a BTD-designated anti-CD38 antibody for AMR, boosting its late-stage pipeline.
2. Hansa Biopharma's positive Phase II imlifidase AMR data, reported in early 2025, reinforces its enzyme-cleaving platform and may accelerate collaborative licensing.
3. Talaris or CSL deal rumored, aligning their complement inhibitor portfolios (no firm public M&A yet), spotlighting increasing deal momentum in AMR biologic innovation.

As per our analysis, these events highlight the sector's strategic direction, focusing on enzyme and biologic innovation, licensing for next-gen AMR assets, and clinical acceleration partnerships rather than traditional consolidation.

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Key Growth Drivers & Emerging Opportunities in the Antibody-Mediated Rejection Market

• Growth in organ transplants, especially among elderly patients, is increasing AMR incidence.
• Breakthroughs in enzyme-based agents like imlifidase are enabling rapid removal of donor-specific antibodies.
• Complement inhibition therapies are gaining momentum as targeted options for AMR prevention and treatment.
• Regulatory support (BTD, Orphan Drug) expedites the development of novel AMR therapies like felzartamab.
• Collaborations and licensing are expanding pipelines in biosimilars, monoclonals, and next-gen biologics.

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Regional Market Drivers for the Antibody-Mediated Rejection Market

North America dominates due to leading transplant volumes, mature immunology R&D, and biotech investment.
Europe sustains growth through robust transplant infrastructure, complement inhibitor adoption, and multi-country clinical studies.
Asia Pacific is rapidly expanding, propelled by increasing transplants, growing AMR awareness, and rising biotech investment.
Latin America, the Middle East & Africa are emerging markets with expanding transplant access and regulatory backing for AMR therapies.

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✅ Sustainability Impact Analysis
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✅ Pipeline Analysis For Drug Discovery
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✅ Market Volatility & Emerging Risks Analysis
✅ Competitive Landscape

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Contact Us -
Company Name: DataM Intelligence
Contact Person: Sai Kiran
Email: Sai.k@datamintelligence.com
Phone: +1 877 441 4866
Website: https://www.datamintelligence.com

About Us -
DataM Intelligence is a Market Research and Consulting firm that provides end-to-end business solutions to organizations from Research to Consulting. We, at DataM Intelligence, leverage our top trademark trends, insights, and developments to provide swift and astute solutions to clients like you. We encompass a multitude of syndicate reports and customized reports with a robust methodology.

Our research database features countless statistics and in-depth analyses across a wide range of 6300+ reports in 40+ domains, creating business solutions for more than 200+ companies across 50+ countries; catering to the key business research needs that influence the growth trajectory of our vast clientele.

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