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Key Factor Supporting Scleroderma Market Development in 2025: Rising Scleroderma Cases Propel Therapeutics Demand

07-11-2025 08:11 AM CET | Health & Medicine

Press release from: The Business Research Company

Scleroderma

Scleroderma

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How Large Will the Scleroderma Market Size By 2025?
The market size of scleroderma has notably expanded in past years. It is projected to rise from a value of $2.33 billion in 2024 up to $2.49 billion in 2025, posting a compound annual growth rate (CAGR) of 6.9%. The upsurge in the previous period is linked to improved diagnostic techniques, advancements in immunological research, development in therapeutics, rising awareness and education, and genetic studies.

How Big Is the Scleroderma Market Size Expected to Grow by 2029?
The market size of scleroderma is anticipated to experience significant expansion in the coming years. It is set to escalate to $3.25 billion by 2029, with a compound annual growth rate (CAGR) of 6.9%. The projected growth during the forecast period could be ascribed to advancements in biological therapies, precision medicine, stem cell therapies, along with genomic and biomarker studies, facilitated by global collaborations. Key trends during the forecasted timeframe include the implementation of digital health solutions, emphasis on microbiome, prioritization of patient-oriented care, advancements in regenerative medicine, as well as health equality and accessibility.

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Which Key Market Drivers Powering Scleroderma Market Expansion and Growth?
The scleroderma market is being propelled by the increasing incidence of the disease. Scleroderma, a long-lasting autoimmune disorder, is identified by the unusual proliferation of collagen, a vital protein that shapes skin and other tissues. A variety of environmental factors could potentially trigger an unchecked immune response, resulting in this ailment. As cases increase, the need for enhanced diagnosis and treatment becomes clear. Therapies for scleroderma play a key role in disease management and symptom relief by controlling the immune response and reducing environmental risk exposure. To illustrate, data from Karger Publishers in Switzerland in June 2022 highlighted that there were 19,000 scleroderma cases in the UK and 2.5 million globally. Moreover, in August 2024, the University of Oxford-affiliated Oxford Academic Press published a research article stating that among 10.1 million individuals in the CPRD, 1,588 cases of systemic sclerosis (SSc) were found, resulting in 206 cancer diagnoses, mainly mucocutaneous (4.5%), lung (2.1%), and breast (1.9%). Consequently, the high prevalence of scleroderma is fueling the scleroderma market.

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Which Fast-Growing Trends Are Poised to Disrupt the Scleroderma Market?
The advancement of innovative treatments is an emerging trend seen within the scleroderma market. Prominent businesses in this sector are putting in efforts to create unique drugs that can control the symptoms and help them retain their market position. For example, in April 2022, US-based biotherapeutics producer, Tyr Pharma Inc., acquired the necessary regulatory consent for its ground-breaking drug efzofitimod, designed to treat systemic sclerosis-related interstitial lung disease, from the US-based health regulation body, the US Food and Drug Administration. This new drug is the only one of its kind designed to regulate and manage the immune response by adjusting the neuropilin-2 (NRP2) receptor to reduce the symptoms of scleroderma. Furthermore, Efzofitimod also is developed to attack the same immune cells that contribute to the pathology of SSc-ILD (interstitial lung disease linked with systemic sclerosis) and pulmonary sarcoidosis, resulting in lower pro-inflammatory markers in a clinical trial comprising patients afflicted with pulmonary sarcoidosis.

What Are the Emerging Segments in the Scleroderma Market?
The scleroderma market covered in this report is segmented -

1) By Treatment: Medication, Surgery, Other Treatments
2) By Indication: Systemic Scleroderma, Localized Scleroderma
3) By End User: Hospital, Pharmaceutical Stores, Other End Users

Subsegments:
1) By Medication: Immunosuppressants, Antifibrotic Agents, Vasodilators, Corticosteroids, Pain Relievers
2) By Surgery: Lung Transplantation, Other Surgical Interventions
3) By Other Treatments: Physical Therapy, Occupational Therapy, Lifestyle Modifications, Alternative Therapies

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Who Are the Global Leaders in the Scleroderma Market?
Major companies operating in the scleroderma market include Pfizer Inc., Johnson And Johnson Inc., F. Hoffmann-La Roche AG, Abbvie Inc., Bayer AG, Novartis AG, Merck And Co. Inc., Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., GSK plc, Teva Pharmaceutical Industries Ltd., Astellas Pharma Inc., Aspen Pharmacare Holdings Limited, Boehringer Ingelheim International GmbH, Principia Biopharma Corp, aTyr Pharma Inc., Cumberland Pharmaceuticals Inc., Kadmon Holdings Inc., Emerald Health Pharmaceuticals Inc., FibroGen Inc., Argentis Pharmaceuticals LLC, Corbus Pharmaceuticals Holdings Inc., H.A.C. Pharma

Which are the Top Profitable Regional Markets for the Scleroderma Industry?
North America was the largest region in the scleroderma market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the scleroderma market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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With over 15,000+ reports from 27 industries covering 60+ geographies, The Business Research Company has built a reputation for offering comprehensive, data-rich research and insights. Our flagship product, the Global Market Model delivers comprehensive and updated forecasts to support informed decision-making.

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