Press release
U.S. DNA Manufacturing Market to Reach US$ 11.72 Billion Growing at 18.14% CAGR From 2025 to 2034
U.S. DNA Manufacturing Market
The U.S. DNA Manufacturing market is valued at USD 2.22 billion in 2024 and is expected to reach approximately USD 11.72 billion by 2034, according to Polaris Market Research. The market is projected to grow at a strong CAGR of 18.14% during the forecast period from 2025 to 2034.
What is U.S. DNA Manufacturing Market?
The U.S. DNA manufacturing market involves the production of synthetic DNA sequences for applications in biotechnology, pharmaceuticals, research, and gene therapy. It includes services like gene synthesis, oligonucleotide production, and DNA sequencing, driven by advancements in synthetic biology and demand for personalized medicine. Key players are biotech firms, contract manufacturers, and research institutions, with growth fueled by innovations in genomics and CRISPR technology.
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What's Propelling Market Forward?
Ongoing innovation, rising demand across key sectors, and supportive industry trends are driving the upward trajectory of the U.S. DNA Manufacturing Market.
Below are some of the primary forces fueling this growth:
• Rising Healthcare Spending:
o Increased healthcare spending in the U.S. is boosting investments in mRNA vaccines and DNA-based diagnostics.
o In 2023, U.S. health spending rose by 7.5% to $4.9 trillion, or $14,570 per capita, according to the American Medical Association.
o Higher funding is accelerating the adoption of gene therapies, CRISPR treatments, and next-gen sequencing, all of which depend on high-quality synthetic DNA.
• Regulatory Support and Accelerated Approvals:
o The FDA and other agencies are simplifying approval processes for mRNA vaccines, gene therapies, and CRISPR-based treatments.
o This support enables faster market entry for innovative therapies, increasing demand for custom-manufactured DNA.
o Government incentives are encouraging startups and pharma companies to invest in DNA-based therapies, driving market growth.
Who Are Market Key Players?
This market features dynamic competition where prominent organizations continuously innovate and pursue strategic alliances to expand their market share and influence.
Key U.S. DNA Manufacturing Market participants include:
• AGC Biologics
• Bionova Scientific
• Catalent
• Charles River Laboratories
• Danaher
• Eurofins Genomics
• GenScript
• Lonza
• Thermo Fisher Scientific
• Twist Bioscience
• VGXI, Inc.
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U.S. DNA Manufacturing Market Report Highlights:
• In terms of type, the plasmid DNA segment accounted for a major market share in 2024. Pharmaceutical and biotechnology companies drove strong demand for plasmid DNA due to its critical role in cell and gene therapies, DNA vaccines, and viral vector production.
• Based on grade, the GMP grade segment held the largest market share in 2024 due to increasing demand for high-quality synthetic DNA in therapeutic applications, including mRNA vaccines, gene therapies, and cell-based treatments.
• In terms of application, the cell & gene therapy segment dominated the market share in 2024 due to increasing advancements in CRISPR-based gene editing, CAR-T cell therapies, and viral vector production.
• Based on end use, the contract research organizations segment is projected to grow at a robust pace in the coming years, owing to the growing trend of outsourcing in drug discovery and clinical trials.
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How Is Market Segmentation Done?
The market segmentation section provides a clearer understanding of demand patterns and growth opportunities across different segments.
The market is segmented based on the following key parameters:
By Type Outlook (Revenue, USD Billion, 2020-2034)
• Plasmid DNA
• Synthetic DNA
o Gene Synthesis
o Oligonucleotide Synthesis
By Grade Outlook (Revenue, USD Billion, 2020-2034)
• GMP Grade
• R&D Grade
By Application Outlook (Revenue, USD Billion, 2020-2034)
• Cell & Gene Therapy
• Vaccines
• Oligonucleotide-based drugs
• Others
By End Use Outlook (Revenue, USD Billion, 2020-2034)
• Pharmaceutical and Biotechnology Companies
• Academic & Research Institutes
• Contract Research Organizations
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Polaris Market Research is a global market research and consulting company. The company specializes in providing exceptional market intelligence and in-depth business research services for PMR's clientele spread across different enterprises. We at Polaris are obliged to serve PMR's diverse customer base present across the industries of healthcare, technology, semiconductors, and chemicals among various other industries present around the world. We strive to provide PMR's customers with updated information on innovative technologies, high-growth markets, emerging business environments, and the latest business-centric applications, thereby helping them always to make informed decisions and leverage new opportunities. Adept with a highly competent, experienced, and extremely qualified team of experts comprising SMEs, analysts, and consultants, we at Polaris endeavor to deliver value-added business solutions to PMR's customers.
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