Medulloblastoma Pipeline Appears Robust With 10+ Key Pharma Companies Actively Working in the Therapeutics Segment | DelveInsight

DelveInsight's, "Medulloblastoma Pipeline Insight, 2025" report provides comprehensive insights about 10+ companies and 12+ pipeline drugs in Medulloblastoma pipeline landscape. It covers the Medulloblastoma pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Medulloblastoma pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

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Key Takeaways from the Medulloblastoma Pipeline Report

* In June 2025, John Yu announced a study is to examine the use of a single dose of tozuleristide (24 or 36 mg) and the Canvas imaging system during surgical resection of primary central nervous system (CNS) tumors: Primary gadolinium enhancing (high grade) CNS tumors, primary non-gadolinium enhancing CNS tumors, and primary vestibular schwannoma.
* In June 2025, Hoffmann-La Roche conducted a Phase 1/2 multicenter dose escalation study in pediatric patients with relapsed or refractory extracranial solid tumors (Phase 1), with additional expansion cohorts (Phase 2) in patients with primary brain tumors harboring NTRK1/2/3 or ROS1 gene fusions, and extracranial solid tumors harboring NTRK1/2/3 or ROS1 gene fusions.
* DelveInsight's Medulloblastoma pipeline report depicts a robust space with 10+ active players working to develop 12+ pipeline therapies for Medulloblastoma treatment.
* The leading Medulloblastoma Companies such as Biodexa Pharmaceuticals, Valent Technologies LLC, Novartis Oncology, Sun Pharmaceutical Industries, Chimerix, Curis and others.
* Promising Medulloblastoma Pipeline Therapies such as CX 4945, LDE225, TMZ, Nifurtimox, Cyclophosphamide, Topotecan, Irinotecan, Temozolomide and others.

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Medulloblastoma Emerging Drugs Profile

* MTX110: Biodexa Pharmaceuticals

MTX110 is a water-soluble form of panobinostat free base, achieved through complexation with hydroxypropyl--cyclodextrin (HPBCD) that enables convection-enhanced delivery (CED) at potentially chemotherapeutic doses directly to the site of the tumour. Panobinostat is a hydroxamic acid and acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor). The currently available oral formulation of panobinostat lactate (Farydak Registered ) is not suitable for treatment of brain cancers owing to poor blood-brain barrier penetration and inadequate brain drug concentrations. Based on favourable translational science data, MTX110 is being evaluated clinically as a treatment for DIPG and recurrent medulloblastoma and preclinically for treatment of glioblastoma. MTX110 is delivered directly into and around the patient's tumour via a catheter system (e.g. CED or fourth ventricle infusions) to bypass the blood-brain barrier. This technique exposes the tumour to very high drug concentrations while simultaneously minimising systemic drug levels and the potential for toxicity and other side effects. Panobinostat has demonstrated high potency against DIPG tumour cells in in vitro and in vivo models, and in a key study it was the most promising of 83 anticancer agents tested in 14 patient-derived DIPG cell lines. Currently the drug is in Phase I stage of development for the treatment of medulloblstoma.

The Medulloblastoma Pipeline Report provides insights into

* The report provides detailed insights about companies that are developing therapies for the treatment of Medulloblastoma with aggregate therapies developed by each company for the same.
* It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Medulloblastoma Treatment.
* Medulloblastoma Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
* Medulloblastoma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
* Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Medulloblastoma market.

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Medulloblastoma Companies

Biodexa Pharmaceuticals, Valent Technologies LLC, Novartis Oncology, Sun Pharmaceutical Industries, Chimerix, Curis and others.

Medulloblastoma Pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

* Oral
* Intravenous
* Subcutaneous
* Parenteral
* Topical

Medulloblastoma Products have been categorized under various Molecule types such as

* Recombinant fusion proteins
* Small molecule
* Monoclonal antibody
* Peptide
* Polymer
* Gene therapy

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Scope of the Medulloblastoma Pipeline Report

* Coverage- Global
* Medulloblastoma Companies- Biodexa Pharmaceuticals, Valent Technologies LLC, Novartis Oncology, Sun Pharmaceutical Industries, Chimerix, Curis and others.
* Medulloblastoma Pipeline Therapies- CX 4945, LDE225, TMZ, Nifurtimox, Cyclophosphamide, Topotecan, Irinotecan, Temozolomide and others.
* Medulloblastoma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
* Medulloblastoma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

For a detailed overview of our latest research findings and future plans, read the full details of Medulloblastoma Pipeline on our website @ Medulloblastoma Emerging Drugs and Companies [https://www.delveinsight.com/sample-request/medulloblastoma-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]

Table of Contents

* Introduction
* Executive Summary
* Medulloblastoma: Overview
* Pipeline Therapeutics
* Therapeutic Assessment
* Medulloblastoma- DelveInsight's Analytical Perspective
* Late Stage Products (Phase III)
* Drug Name: Company Name
* Drug profiles in the detailed report.....
* Mid Stage Products (Phase II)
* Drug Name: Company Name
* Drug profiles in the detailed report.....
* Early Stage Products (Phase I)
* MTX110: Biodexa Pharmaceuticals
* Drug profiles in the detailed report.....
* Preclinical and Discovery Stage Products
* Drug Name: Company Name
* Drug profiles in the detailed report.....
* Inactive Products
* Medulloblastoma Key Companies
* Medulloblastoma Key Products
* Medulloblastoma- Unmet Needs
* Medulloblastoma- Market Drivers and Barriers
* Medulloblastoma- Future Perspectives and Conclusion
* Medulloblastoma Analyst Views
* Medulloblastoma Key Companies
* Appendix

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