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CAR T-Cell Therapy Market to Reach US$ 23.4 Bn by 2031 Driven by Cancer Treatment Demand

06-18-2025 06:57 AM CET | Health & Medicine

Press release from: Persistence Market Research

CAR T-Cell Therapy Market

CAR T-Cell Therapy Market

✅CAR T-Cell Therapy Market: Transforming Oncology with Precision Immunotherapy

The CAR T-cell therapy market is rapidly evolving as an innovative approach in cancer immunotherapy, promising personalized and durable treatment outcomes. Chimeric Antigen Receptor (CAR) T-cell therapy, which modifies patients' T-cells to attack cancer, has emerged as a frontline solution for hematologic malignancies and is being tested for solid tumors. In 2024, the global market value stands at US$ 5.6 billion, with expectations to surge to US$ 23.4 billion by 2031, exhibiting a CAGR of 22.5%.

The key growth drivers include increased incidence of cancer globally, advancements in cell engineering, and FDA approvals for CAR T-cell products. Among all segments, hematologic cancer therapies lead the market, driven by their strong clinical success and approved indications. Regionally, North America dominates the CAR T-cell therapy market, attributed to robust healthcare infrastructure, favorable reimbursement policies, and a high number of clinical trials.

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✅Key Highlights from the Report

➤The CAR T-cell therapy market is forecast to expand at a 22.5% CAGR from 2024 to 2031
➤Global market value expected to rise from US$ 5.6 Bn in 2024 to US$ 23.4 Bn by 2031
➤North America remains the leading region due to advanced healthcare systems
➤Hematologic malignancy treatments dominate the product type segment
➤Adoption is rising in Asia Pacific due to expanding clinical trial activity
➤Growing FDA and EMA approvals for new therapies spur industry momentum

✅Frequently Searched Question

What are the major challenges facing the CAR T-cell therapy market?

While CAR T-cell therapy holds tremendous promise in oncology, several challenges restrict its broader application. One of the primary concerns is the high cost of treatment, often exceeding hundreds of thousands of dollars, making it inaccessible for many patients, especially in low- and middle-income countries. Additionally, manufacturing complexities-including the individualized nature of the therapy-require sophisticated facilities and logistical precision, leading to delays in patient treatment. Another major challenge is managing side effects such as cytokine release syndrome (CRS) and neurotoxicity, which demand close clinical monitoring and can affect treatment success. Further, despite remarkable efficacy in hematological cancers, limited results in solid tumors present another hurdle. Addressing these challenges requires innovation in allogeneic ("off-the-shelf") CAR T-cell platforms, improved safety mechanisms, and better manufacturing scalability to support growing demand.

✅Market Segmentation

The CAR T-cell therapy market is segmented based on product type, primarily into autologous and allogeneic therapies. Autologous therapy, where a patient's own cells are used, currently dominates due to higher compatibility and success rates. However, allogeneic approaches are gaining traction as they offer scalable, off-the-shelf solutions that reduce manufacturing timelines and costs.

By end-user, the market is divided into hospitals, cancer treatment centers, and academic research institutes. Hospitals hold the largest share due to their access to resources and trained personnel to administer complex cell therapies. Research institutes are instrumental in driving innovation and initiating early-phase clinical trials, supporting continuous pipeline expansion.

✅Regional Insights

In North America, especially the U.S., strong funding, a high number of approved CAR T-cell therapies, and early adoption contribute to the region's dominance. The presence of key pharmaceutical companies and favorable regulatory frameworks further reinforce this leadership.

Meanwhile, Asia Pacific is emerging as a lucrative region, propelled by increasing cancer burden, government investment in biotechnology, and rising participation in clinical trials. Countries like China and Japan are advancing their CAR T-cell therapy pipelines, enhancing regional competitiveness.

✅Market Dynamics

Market Drivers

The surge in cancer prevalence worldwide acts as a primary driver for CAR T-cell therapy demand. Rising awareness of immunotherapy benefits, the shift toward personalized medicine, and increasing approvals for novel indications (like multiple myeloma and lymphoma) also accelerate market growth.

Market Restraints

Despite significant advances, the market is hindered by cost barriers, long production timelines, and limited availability of treatment centers. Side effects such as CRS and neurotoxicity create further concerns for physicians and regulatory bodies. Moreover, insurance coverage varies widely, impacting patient access.

Market Opportunities

Opportunities lie in expanding indications beyond blood cancers to include solid tumors. Innovations like next-gen CAR constructs, allogeneic platforms, and AI-supported manufacturing promise greater efficiency and scalability. Emerging markets in Asia and Latin America offer untapped potential due to growing healthcare investments and patient populations.

✅Reasons to Buy the Report

☑️Gain deep insights into the CAR T-cell therapy market trends, forecasts, and growth drivers
☑️Understand competitive positioning and strategies of leading companies globally
☑️Access detailed market segmentation by product, end-user, and geography
☑️Track the latest regulatory approvals and clinical developments in the sector
☑️Make informed investment and R&D decisions with strategic recommendations

✅Company Insights

✦Gilead Sciences, Inc.
✦Novartis AG
✦Bristol-Myers Squibb Company
✦Legend Biotech Corporation
✦Johnson & Johnson
✦Kite Pharma
✦Bluebird Bio, Inc.
✦Autolus Therapeutics
✦Caribou Biosciences
✦Sorrento Therapeutics

■In February 2024, Legend Biotech announced the launch of a Phase 3 clinical trial for its investigational CAR T-cell therapy targeting solid tumors.

■In April 2024, Kite Pharma received expanded FDA approval for Yescarta to treat relapsed large B-cell lymphoma after one prior therapy.

✅Conclusion

The global CAR T-cell therapy market is undergoing a transformative expansion driven by scientific innovation, patient demand for advanced treatment, and growing regulatory support. With an impressive CAGR of 22.5% from 2024 to 2031, the market is poised to redefine oncology care across the world. While challenges persist-particularly in terms of cost, access, and scalability-the future remains highly promising as industry leaders continue to break barriers through clinical research and next-gen platforms. For stakeholders, this dynamic and high-growth market offers abundant opportunities for investment, innovation, and global impact in the realm of precision medicine.

✅About Persistence Market Research:

At Persistence Market Research, we specialize in creating research studies that serve as strategic tools for driving business growth. Established as a proprietary firm in 2012, we have evolved into a registered company in England and Wales in 2023 under the name Persistence Research & Consultancy Services Ltd. With a solid foundation, we have completed over 3600 custom and syndicate market research projects, and delivered more than 2700 projects for other leading market research companies' clients.

Our approach combines traditional market research methods with modern tools to offer comprehensive research solutions. With a decade of experience, we pride ourselves on deriving actionable insights from data to help businesses stay ahead of the competition. Our client base spans multinational corporations, leading consulting firms, investment funds, and government departments. A significant portion of our sales comes from repeat clients, a testament to the value and trust we've built over the years.

✅Contact Us:

Persistence Market Research
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Brentford, London, TW8 0GU UK
USA Phone: +1 646-878-6329
UK Phone: +44 203-837-5656
Email: sales@persistencemarketresearch.com
Web: https://www.persistencemarketresearch.com

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