Multicancer Screening Market Accelerates with Technological Integration Across DNA RNA and Protein-Based Detection Platforms

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Multicancer Screening Market Size, Share & Trends Analysis Report By Test Type (Laboratory Developed Tests (LDTs) and In-Vitro Diagnostics (IVDs)), Technology (Next-Generation Sequencing (NGS), Polymerase Chain Reaction (PCR), Immunohistochemistry (IHC), Fluorescence In-Situ Hybridization (FISH)), Sample (Tissue, Blood, Saliva, Buccal Swabs), Method (DNA, RNA, and Proteins), Cancer Type (Breast and Gynecologic, Gastrointestinal, Endocrine, Genitourinary, Skin, Brain/Nervous System, Sarcoma, Hematological Malignancies, Lung, Head and Neck), Application (Clinical and Research), And End-User (Hospitals, Diagnostic and Clinical Laboratories, Academic and Research Institutions)- Market Outlook And Industry Analysis 2031"

The global Multicancer Screening market is estimated to reach over USD 6.57 billion by 2031, exhibiting a CAGR of 15.32% during the forecast period.

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The multi-cancer early detection (MCED) market is expected to witness substantial growth, primarily driven by the increasing global incidence of cancer and heightened governmental focus on early detection initiatives. According to the World Health Organization (WHO), cancer accounted for approximately 10 million deaths in 2020, representing nearly one in six deaths globally, thereby making it the leading cause of mortality worldwide. Contributing factors include tobacco use, elevated body mass index, alcohol consumption, obesity, and high cholesterol levels, which together account for nearly one-third of all cancer-related deaths.

Growing public awareness of the benefits of early cancer detection-such as improved survival outcomes and reduced treatment costs-is contributing to the expanding adoption of MCED technologies. Numerous hospitals and community health centers are actively working to enhance cancer screening rates. However, the COVID-19 pandemic caused a sharp decline in screening activities in 2020 due to operational disruptions, staffing shortages, and public hesitancy to visit healthcare facilities for non-urgent procedures. By 2021 and 2022, screening volumes began to normalize as healthcare services resumed regular operations.

The market is further bolstered by advancements in diagnostic technologies capable of detecting multiple cancer types through a single test-especially for cancers that currently lack standard screening methods. The emergence of liquid biopsy platforms and innovations by key industry players such as GENECAST, GRAIL, and Thrive Earlier Detection are significantly expanding the capabilities of MCED solutions and opening new avenues for market development.

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List of Prominent Players in the Multicancer Screening Market:
• Agilent Technologies, Inc.
• Atara Biotherapeutics, Inc.
• Burning Rock DX
• Danaher Corporation
• Exact Sciences Corporation
• F. Hoffmann-La Roche Ltd
• Fulgent Genetics.
• Genecast Biotechnology Co., Ltd
• Guardant Health, Inc.
• Illumina, Inc.
• Konica Minolta, Inc.
• Laboratory Corporation of America Holdings.
• Myriad Genetics, Inc.
• Tempus
• Thermo Fisher Scientific Inc.

Market Dynamics
Drivers:
The multi-cancer early detection (MCED) market is poised for significant growth, driven by increasing adoption of early detection technologies across hospital and laboratory settings. Heightened awareness and governmental initiatives promoting early cancer diagnosis are key contributors to this upward trajectory. For instance, the World Health Organization (WHO) supports member states in the design and implementation of early diagnosis and screening programs that are both feasible and cost-effective, in an effort to reduce diagnostic delays and enhance treatment outcomes. These initiatives are expected to substantially accelerate the adoption of MCED solutions, resulting in robust market expansion.

Challenges:
A major challenge facing the MCED market is the need to generate comprehensive safety and efficacy data to secure regulatory approval. Obtaining this evidence is particularly complex, as traditional cancer screening tests have primarily relied on long-term data from prospective and observational studies, and short-term outcomes from randomized controlled trials (RCTs) and post-marketing epidemiological research. The validation of MCED tests, particularly those targeting rare cancers, presents logistical hurdles in establishing clinically meaningful evidence. In response, the National Cancer Institute (NCI) has issued a request for information from test developers regarding their readiness to engage in clinical trials and related research activities to support regulatory and clinical validation.

Regional Trends:
Europe currently holds a dominant share of the MCED market, attributed to increased investments in research and development as well as a rising cancer incidence across the region. A notable example is the EU-funded DeteCTCs initiative, which aims to advance cancer diagnostics and treatment by accelerating the commercialization of innovative technologies. The project's core innovation, CellMate, employs advanced circulating tumor cell capture methods, next-generation DNA sequencing, and artificial intelligence-driven bioinformatics to detect multiple cancer types from a single blood sample at an early stage. This underscores Europe's strong position in driving technological innovation within the MCED landscape.

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Recent Developments:
• In December 2022, The LENA Q51(R) launch has been scheduled for January 2023, according to Alercell. It is a DNA-based diagnostic test for leukaemia that can find up to 51 gene abnormalities in those who have the disease.
• In June 2022, A CE mark was awarded to Burning Rock Biotech Limited for its OverC multi-cancer detection blood test. A high-quality in vitro diagnostic tool based on next-generation sequencing (NGS) is the OverC Multi-Cancer Detection Blood Test.

Segmentation of Multicancer Screening Market-
By Test Type-
• Laboratory Developed Tests (LDTs)
• In-Vitro Diagnostics (IVDs)
By Technology-
• Next-Generation Sequencing (NGS)
• Polymerase Chain Reaction (PCR)
• Immunohistochemistry (IHC)
• Fluorescence In-Situ Hybridization (FISH)
• Other Technologies
By Sample-
• Tissue
• Blood
• Saliva and Buccal Swab
• Others
By Method -
• DNA
• RNA
• Proteins
By Cancer Type-
• Breast and Gynecologic
• Gastrointestinal
• Endocrine
• Genitourinary
• Skin
• Brain/Nervous System
• Sarcoma
• Hematological Malignancies
• Lung
• Head and Neck
• Other Cancer Types
By Application -
• Clinical
• Research
By End User -
• Hospitals
• Diagnostic and Clinical Laboratories
• Academic and Research Institutions
• Other End Users
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• Southeast Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of Middle East and Africa

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This release was published on openPR.