Press release
Advanced Renal Cell Carcinoma Therapeutics Market Size in 7MM is expected to grow at a decent CAGR by 2034, estimates DelveInsight
Discover which therapies are expected to grab the Advanced Renal Cell Carcinoma Market Share @ Advanced Renal Cell Carcinoma Market Outlook [https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Key Takeaways from the Advanced Renal Cell Carcinoma Market Report
* In June 2025, Karie Runcie announced a study population for this Phase 2 study will include men and women greater than or equal to 18 with confirmed renal cell carcinoma who have progressed on adjuvant anti-PD-1/PD-L1 therapy, the current standard of care. Subjects will be randomized to Arm A or Arm B. Study treatment will be given in 28-day (4 week) cycles. Arm A treatment will consist of XL092 alone and will be taken once daily continuously (Day 1-Day 28). Arm B treatment will consist of XL092 plus nivolumab. XL092 will be taken once daily continuously (Day 1-Day 28) and nivolumab will be administered every 4 weeks (Day 1). Treatment will continue until progression by RECIST 1.1, toxicity, or other reasons as appropriate.
* In June 2025, Bristol-Myers Squibb announced a study is to determine whether Nivolumab Combined with Cabozantinib is safe and effective compared to Sunitinib in previously untreated advanced or metastatic renal cell carcinoma.
* According to findings, renal cell carcinoma accounts for 90% of all kidney cancers.
* One in three people with renal cell carcinoma receive a diagnosis at the metastatic stage.
* RCC predominantly affects the male population, with men being significantly more susceptible as compared to women.
* There are several types of RCC, but 75% of patients have a type called clear cell.
* Several factors can be attributed to an increased risk of RCC, including smoking, obesity, and high blood pressure and having a family history of certain conditions, such as von Hippel-Lindau disease, a rare genetic multi-system disorder characterized by abnormal blood vessel growth.
* RCC is difficult to detect in its early stages, and >30% patients with RCC have metastatic, or advanced, cancer at the time of diagnosis, meaning the cancer cells have spread beyond the kidney to other parts of the body.
* The leading Advanced Renal Cell Carcinoma Companies such as CoImmune, Merck & Dohme, Xynomic Pharmaceuticals, NiKang Therapeutics and others.
* Promising Advanced Renal Cell Carcinoma Pipeline Therapies such as Bevacizumab, Atezolizumab, TQB2450, Anlotinib, Sunitinib, HB0025, Botensilimab, Balstilimab, Ipilimumab and others.
Stay ahead in the Advanced Renal Cell Carcinoma Therapeutics Market with DelveInsight's Strategic Report @ Advanced Renal Cell Carcinoma Treatment Market [https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Advanced Renal Cell Carcinoma Epidemiology Segmentation in the 7MM
* Advanced Renal Cell Carcinoma Incident Cases of Kidney Cancer
* Advanced Renal Cell Carcinoma Incident Cases
* Advanced Renal Cell Carcinoma Subtype-specific Incident
* Advanced Renal Cell Carcinoma Stage-specific Incident Cases
* Advanced Renal Cell Carcinoma Gender-specific Incident Cases
* Advanced Renal Cell Carcinoma Diagnosed and Treated Cases
Download the report to understand which factors are driving Advanced Renal Cell Carcinoma Epidemiology trends @ Advanced Renal Cell Carcinoma Prevalence [https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Marketed Advanced Renal Cell Carcinoma Drugs
* KEYTRUDA (pembrolizumab): Merck
It is a highly selective humanized monoclonal IgG4 antibody directed against the PD-1 receptor on the cell surface. The drug blocks the PD-1 receptor, preventing binding and activation of PD-L1 and PD-L2. This mechanism causes the activation of T-cell mediated immune responses against tumor cells. In April 2019, the FDA approved pembrolizumab plus axitinib for the first-line treatment of patients with advanced renal cell carcinoma
* WELIREG (belzutifan): Merck
Belzutifan is an inhibitor of hypoxia-inducible factor 2 alpha (HIF-2). HIF-2 is a transcription factor that plays a role in oxygen sensing by regulating genes that promote adaptation to hypoxia. Under normal oxygen levels, HIF-2 is targeted for ubiquitin-proteasomal degradation by VHL protein. In December 2023, the US FDA WELIREG, an oral hypoxia-inducible factor-2 alpha (HIF-2) inhibitor, for the treatment of adult patients with advanced renal cell carcinoma.
Emerging Advanced Renal Cell Carcinoma Drugs
* Zanzalintinib (XL092) + Nivolumab: Exelixis/BMS
Zanzalintinib represents a nextgeneration oral TKI designed to inhibit the activity of receptor tyrosine kinases associated with cancer growth and spread. These include VEGF receptors, MET, AXL, and MER, which play crucial roles in various cellular functions and pathological processes such as oncogenesis, metastasis, and tumor angiogenesis. Zanzalintinib builds upon Exelixis' extensive experience with cabozantinib, their flagship medicine, aiming to enhance key characteristics like pharmacokinetic halflife.
* Savolitinib + Durvalumab: AstraZeneca/HUTCHMED
Savolitinib is an investigational inhibitor of the mesenchymal-epithelial transition factor, or MET receptor tyrosine kinase, an enzyme that has been shown to function abnormally in many types of solid tumors. We designed savolitinib through chemical structure modification to specifically address kidney toxicity, the primary issue that halted the development of several other selective MET inhibitors
To learn more about Advanced Renal Cell Carcinoma Treatment guidelines, visit @ Advanced Renal Cell Carcinoma Clinical Trials Assessment [https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Advanced Renal Cell Carcinoma Companies
CoImmune, Merck & Dohme, Xynomic Pharmaceuticals, NiKang Therapeutics and others.
Advanced Renal Cell Carcinoma Market Outlook
Advanced Renal Cell Carcinoma companies, including Exelixis, Bristol-Myers Squibb (BMS), AstraZeneca, and HUTCHMED, are actively evaluating their lead candidates at various stages of clinical development, focusing on the treatment of advanced renal cell carcinoma. The Advanced Renal Cell Carcinoma market outlook appears promising, driven by these companies' efforts to innovate and expand the therapeutic arsenal. As these investigational therapies progress through clinical trials, they hold the potential to significantly improve patient outcomes and address unmet needs in advanced renal cell carcinoma management. The competitive landscape is poised for dynamic growth, with advancements in targeted therapies, immunotherapies, and combination treatments, ultimately aiming to enhance survival rates and quality of life for patients.
Learn more about the FDA-approved drugs for Advanced Renal Cell Carcinoma @ Drugs for Advanced Renal Cell Carcinoma Treatment [https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Scope of the Advanced Renal Cell Carcinoma Market Report
* Coverage- 7MM
* Study Period- 2020-2034
* Advanced Renal Cell Carcinoma Companies- CoImmune, Merck & Dohme, Xynomic Pharmaceuticals, NiKang Therapeutics and others.
* Advanced Renal Cell Carcinoma Pipeline Therapies- Bevacizumab, Atezolizumab, TQB2450, Anlotinib, Sunitinib, HB0025, Botensilimab, Balstilimab, Ipilimumab and others.
* Advanced Renal Cell Carcinoma Market Dynamics: Advanced Renal Cell Carcinoma Market Drivers and Barriers
* Advanced Renal Cell Carcinoma Market Access and Reimbursement, Unmet Needs and Future Perspectives
Table of Contents
1. Key Insights
2. Report Introduction
3. Executive Summary of Advanced Renal Cell Carcinoma (RCC)
4. Key Events
5. Advanced Renal Cell Carcinoma Epidemiology and Market Forecast Methodology
6. Advanced Renal Cell Carcinoma Market Overview at a Glance
7. Disease Background and Overview: RCC
8. Advanced Renal Cell Carcinoma Treatment and Management
9. Epidemiology and Patient Population of RCC in Latin America and Canada
10. Advanced Renal Cell Carcinoma Patient Journey
11. Key Endpoints in Advanced RCC
12. Marketed Advanced Renal Cell Carcinoma Therapies
13. Emerging Advanced Renal Cell Carcinoma Therapies
14. Advanced RCC: the US, EU4& the UK and Japan
15. Advanced Renal Cell Carcinoma Unmet Needs
16. Advanced Renal Cell Carcinoma SWOT Analysis
17. Advanced Renal Cell Carcinoma KOL Views
18. Advanced Renal Cell Carcinoma Market Access and Reimbursement
19. Appendix
20. DelveInsight Capabilities
21. Disclaimer
22. About DelveInsight
About Us
DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.
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